Theses
Theses
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PhD
UNDERWAY
Inês Mota (2024.03484.BDANA). Targeting pancreatic cancer with a first-in-class inhibitor of DNA damage repair: seeking for optimized derivatives. PhD in Pharmaceutical Sciences.
Catarina Matos (2023.154513.BD). PhD in Molecular and Cellular Biotechnology Applied to Health Sciences.
Carla Carvalho (2021.06305.BD). PhD in Pharmaceutical Sciences.
Juliana Calheiros (2020.04613.BD). Targeting BRCA1/2-Mediated DNA repair for personalized cancer prevention and therapy. PhD in Pharmaceutical Sciences.
Joana Almeida (2020.05026.BD). Improving neuroblastoma therapy with p53 family-targeting agents. PhD in Pharmaceutical Sciences.
CONCLUDED
Joana B. Loureiro (SFRH/BD/128673/2017). New opportunities in skin cancer prevention and treatment by targeting p53. PhD in Pharmaceutical Sciences. Concluded on 12/04/2022.
Liliana Raimundo (SFRH/BD/117949/2016). Targeting BRCA1 and p53 family of tumor supressors in cancer. Doctoral Programme on Cellular and Molecular Biotechnology Applied to Health Sciences (BiotechHealth). Concluded on 24/09/2020.
Helena Ramos (SFRH/BD/119144/2016). Seeking for new p53-activating agents: effective therapies for colorectal cancer. Doctoral Programme on Cellular and Molecular Biotechnology Applied to Health Sciences (BiotechHealth). Concluded on 09/09/2020.
Ana Sara Gomes (PD/BD/114046/2015). New anticancer drug candidates by targeting p53/p73: structural studies and nanodelivery systems. Doctoral Programme on Cellular and Molecular Biotechnology Applied to Health Sciences (BiotechHealth), specialised in Biotecnologia. Concluded on 17 /09/2019.
Sara Gomes Moreira (FCT - SFRH/BD/96189/2013). Drugging p53-impaired tumors: impact of new small molecules targeting p73 and mutant p53. Doctoral Programme on Cellular and Molecular Biotechnology Applied to Health Sciences (BiotechHealth), specialised in Biotecnologia. Concluded on 16/09/2019.
Cláudia Bessa (SFRH/BD/87109/2012). Targeted modulation of p53/PKC network: Searching for new therapeutic strategies against cancer. PhD in Pharmaceutical Sciences. Concluded on 19/07/2018.
Joana Oliveira Gama Soares (SFRH/BD/78971/2011). Targeting p53 in cancer: from innovative yeast screening strategies to new drugs. PhD in Pharmaceutical Sciences. Concluded on 21/04/2016.
Mariana Valência Castanheira Ferreira Leão (FCT - SFRH/BD/64184/2009). Development of new yeast-based assays to study p53 family proteins: identification of new small molecule modulators. PhD in Pharmaceutical Sciences. Concluded on 16/12/2014.
Maria Inês de Castro (FCT - SFRH/BD/41682/2007). Characterization of mitochondrial stress pathways in neurodegeneration using Drosophila melanogaster as a model system. Concluded on 27/12/2012.
Isabel Cristina Loureiro Coutinho (FCT - SFRH/BD/36066/2007). Use of yeast in the study of mammalian proteins involved in cell survival/death processes and in the screening of their pharmacological modulators. Concluded on 20/12/2011.
Rui Filipe Silva (FCT- SFRH/BD/23774/2005). A new approach for the study of individual PKC isoform modulation of Bcl-2/Bax mediated cell survival: searching for apoptosis based-therapeutic agents. Concluded on 1/07/2011.
MSc
UNDERWAY
Maria Lima. Master degree in Oncology, ICBAS (2024/2025)
CONCLUDED
Rita Silva. BBIT20 as a new anticancer drug candidate for pancreatic cancer treatment: study of the antitumor activity and mechanism of action. Master degree in Biochemistry, FCUP/ICBAS. Concluded on October 2024.
João Morais. Targeting BRCA1-mediated DNA repair in pancreatic ductal adenocarcinoma therapy. Master degree in Oncology, ICBAS. Concluded on December 2023.
Pedro Gomes. Seeking for inhibitors of leucine-rich repeat kinase 2 (LRRK2) as a therapeutic strategy for Parkinson's disease. Master degree in Pharmaceutical Chemistry, FFUP. Concluded on September 2023.
Inês Mota. Seeking optimized TAp73-targeting agents for neuroblastoma treatment. Master degree in Oncology, ICBAS. Concluded on October 2022.
Adriana Gomes. Targeting BRCA1-mediated DNA repair in pancreatic ductal adenocarcinoma therapy. Master degree in Biochemistry, FCUP/ICBAS. Concluded on October 2022.
Rita Ribeiro. Seeking new therapeutic opportunities for Skin Cancer prevention using p53-targeting agents. Master Degree in Biochemistry, FCUP/ICBAS. Concluded on October 2021.
Mariana Silva. Master Degree in Pharmaceutical Chemistry, FFUP. Concluded on 2021.
Rute Pinheiro. Improving cancer therapy with new p53-activating agents. Master Degree in Oncology, ICBAS, University of Porto. Concluded on November 2019.
Joana Almeida. Chalcone derivatives: promising starting points for the discovery of new diarylpentanoids with p53-MDM2/X inhibitory activity. Master Degree in Pharmaceutical Chemistry, FFUP. Concluded on July 2019.
Beatriz Silva. Targeting p53 in anticancer therapy: Searching for new small molecule activators. Master Degree in Oncology, ICBAS, University of Porto. Concluded on July 2018.
Bryan Fernandes. Identification of selective activators of protein kinase C isoforms from a library of semi-synthetic derivatives of natural terpenoids isolated from Plectranthus grandidentatum. Master Degree in Molecular Biology, Biotechnology and Bioentrepreneurship in Plants, University of Minho. Concluded on January 2017.
Joana B Loureiro. Reactivation of p53 as anticancer strategy. Master Degree in Biochemistry, FCUP/ICBAS, University of Porto. Concluded on December 2016.
Helena Ramos. Targeting p53 family in cancer: search for inhibitors of the p53/p73 interaction with MDMs. Master Degree in Bioengineering - Molecular Biotechnology, FEUP, University of Porto. Concluded on October 2015.
Mariana Santos. Developing synthetic tools to image and modulate the activity of carboxyl terminus of Hsc70-interacting protein (CHIP). Master Degree in Biochemistry, FCUP/ICBAS, University of Porto. Concluded on October 2015.
Agostinho Lemos. Design and synthesis of aminoxanthone derivatives as promising disruptors of p53:MDM2 interaction. Master Degree in Pharmaceutical Chemistry, FFUP. Concluded on October 2015.
Joana Moreira. Promising caspases modulators with flavonoid scaffold. Master Degree in Pharmaceutical Chemistry, FFUP. Concluded on October 2015.
Verónica Costa. Searching for new potential small-molecule modulators of pro-apoptotic proteins using the yeast-based screening assay. Master Degree in Pharmaceutical Chemistry, FFUP. Concluded on July 2015.
Liliana Raimundo. Drugging p53 in cancer: From yeast to human cells. Master Degree in Molecular Oncology, ICBAS/University of Porto. Concluded on November 2014.
Liliana Gonçalves. Estudo do envolvimento da via das caspases na atividade antitumoral da frutalina nativa e recombinante. Master Degree in Biomedical Engineering, University of Minho. Concluded on November 2014.
Sara Gomes Moreira. Searching for small-molecule modulators of p53 family proteins. Master Degree in Biochemistry, FCUP/ICBAS, University of Porto. Concluded on November 2013.
Sofia Emanuela Soares Mendonça. Elucidação dos mecanismos moleculares subjacentes ao efeito citotóxico da frutalina nativa e recombinante em células tumorais humanas. Master Degree in Biomedical Engineering, University of Minho. Concluded on November 2013.
Edite Dias. Utilização da levedura como sistema de produção de uma proteína da cápside de um novo norovirus. Master Degree in Molecular Biology and Genetics, University of Minho. Concluded on January 2012.
Cláudia Bessa. Estudo da função da via da ceramida na apoptose induzida por ácido acético e da sua regulação pelas isoformas da cinase C de proteínas. Master Degree in Molecular Biology and Genetics, University of Minho. Concluded on January 2012.
UNDERGRADUATE
CONCLUDED
João Carvalho. Seeking for new preventive agents against skin cancer formation by targeting the mutant p53 pathway. Degree in Biochemistry, FCUP/ICBAS (2022/2023).
Rita Silva. Targeting BRCA1-mediated DNA repair in pancreatic ductal adenocarcinoma therapy. Degree in Biochemistry, FCUP/ICBAS (2021/2022).
Mariana Fernandes. Searching for new preventive anticancer agents by targeting the p53 pathway. Degree in Biology, FCUP (2021/2022).
Ana Filipa Bessa. Targeting BRCA1 and BRCA2 tumour suppressor proteins in breast and ovarian cancers. Degree in Biochemistry, FCUP/ICBAS (2020/2021).
Ana Mafalda Silva. Targeting BRCA1 tumour suppressor protein: searching for new effective anticancer therapeutic options. Degree in Biology, FCUP/ICBAS (2020/2021).
José Silva. Improving Colon Cancer Therapy with a New Mutant P53-Targeting Agent. Internship in the Degree in Biochemistry, FCUP/ICBAS (2019/2020).
Beatriz Gomes Domingues. Targeting BRCA1 tumour suppressor protein: searching for new effective anticancer therapeutic options. Degree in Biochemistry, FCUP/ICBAS (2019/2020).
Cláudia Martins Chaves. Pesquisa de ativadores de formas mutadas da p53 com atividade antitumoral. Curricular Unit of Project I of the Master degree in Pharmaceutical Sciences, FFUP (2019/2020).
Hugo Glória. Search for activators of mutant p53 with antitumoral activity. Curricular Unit of Project I of the Master degree in Pharmaceutical Sciences, FFUP (2018/2019).
Rita Ribeiro. Searching for new therapeutic opportunities in skin cancer prevantion and treatment by targeting p53. Internship in the Degree in Biochemistry, FCUP/ICBAS. (2018/2019)
Ana Beatriz Sousa Pinto. Discovery of MANIO-1: a new selective p53 activator. Internship in the Degree in Biochemistry, FCUP/ICBAS (2016/2017).
Isabel Câmara Furtado. Reactivation of mutant p53 by SLMP53-1: effect on tumor metabolism. Internship in the Degree in Biochemistry, FCUP/ICBAS (2015/2016).
Mariana Lopes Constante. Development of a microbial system for functional and pharmacological studies of p53 mutants. Curricular Unit of Project I of the Master degree in Pharmaceutical Sciences, FFUP (2015/2016).
Ana Rita Fernandes dos Santos. Protein kinase C isoforms: modulation by small-molecules and their impact on mutant p53. Degree in Biology, Faculty of Sciences of University of Porto, FCUP (2014/2015).
Helena Ramos. Searching for inhibitors of the p53 interaction with MDM2 and MDMX: from yeast to human cells. Master degree in Bioengineering, ICBAS, FEUP (2013/2014).
Joana Machado. Estudos funcionais e farmacológicos de mutantes da proteína p53 humana utilizando a levedura como modelo celular. Curricular Unit of Project I of the Master degree in Pharmaceutical Sciences, FFUP (2013/2014).
Carlos Fernandes. Síntese de calconas com potencial atividade na p53. Curricular Unit of Project I of the Master degree in Pharmaceutical Sciences, FFUP (2013/2014).
Hugo Bacelo. Using yeast to study p53 mutants: regulation by protein kinase c isoforms. Master degree in Bioengineering, ICBAS, FEUP (2012/2013).
Raquel de Oliveira Pereira (Universidade Estadual de Goiás; Mobility studenter under the Programme "Ciências sem Fronteiras"). Utilização da levedura Saccharomyces cerevisiae na pesquisa de ativadores da p53 e de inibidores da interação p53-MDM2/MDMX. Curricular Unit of Projeto II of the Master degree in Pharmaceutical Sciences, FFUP (2012/2013).
Tânia Coelho. Implementação de um ensaio com células de levedura para a pesquisa de ativadores da caspase-6 humana. Curricular Unit of Project I of the degree in Pharmaceutical Sciences, FFUP (2012/2013).
Joana Coelho. Implementação de um ensaio com células de levedura para a pesquisa de ativadores da caspase-3 humana. Curricular Unit of Project I of the degree in Pharmaceutical Sciences, FFUP (2012/2013).
Sylvie Carvalho. Otimização hit-to-lead de um inibidor da interação p53-MDM2. Curricular Unit of Project I of the degree in Pharmaceutical Sciences, FFUP (2012/2013).
Daniela Pereira. Síntese de calconas com potencial atividade na p53. Curricular Unit of Project I of the degree in Pharmaceutical Sciences, FFUP (2012/2013).
Ana Pereira. Obtenção por modificação molecular de flavonoides naturais de potenciais agentes moduladores de caspases. Curricular Unit of Project I of the degree in Pharmaceutical Sciences, FFUP (2012/2013).
Samara Nunes Salomão (Universidade Estadual de Goiás; Mobility studenter under the Programme "Ciências sem Fronteiras"). Pesquisa de compostos moduladores da interação p53-MDM2 utilizando levedura como modelo celular. Curricular Unit of Project II of the degree in Pharmaceutical Sciences, FFUP (2011/2012).
Diana Costa. Utilização da levedura Saccharomyces cerevisiae na pesquisa de inibidores da interacção p53-MDM2/MDMX. Curricular Unit of Project I of the degree in Pharmaceutical Sciences, FFUP (2011/ 2012).
Cristina Baptista. Pesquisa de compostos moduladores da actividade de membros da família das caspases, utilizando a levedura como modelo celular. Curricular Unit of Project I of the degree in Pharmaceutical Sciences, FFUP (2009/2010).
Joana Soares. Análise fenotípica e pesquisa de supressores da proteína humana LRRK2/mutante no sistema celular da levedura. Curricular Unit of Project I of the degree in Pharmaceutical Sciences, FFUP (2009/2010).
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