UNDERWAY

CONCLUDED

Targeting p53 family proteins: on the route to new anticancer agents

Navigating through marine­-derived fungi: bioprospection and synthesis of bioactive secondary metabolites and analogues as chemotherapic agents

Functional, molecular and pharmacological studies of p53 family proteins: from yeast to human cells

Functional and pharmacological studies of p53 family proteins: screening for selective small-molecule modulators

Y1 receptor based therapy for local bone repair: Antagonist behavior and delivery in challenged bone microenvironment

Regulation of Bax activation by the oncogene PKCε: An approach to eliminate cancer cells

Novel canine norovirus: molecular, epidemiologic and pathogenic aspects

Expression in yeast of a novel canine norovirus nucleocapsid protein for use in serological studies

Searching for small-molecule modulators of caspase family members using yeast cell-based approaches

Modeling and managing fungal colonization and inflammatory progression on cystic fibrosis patients

A yeast-based phenotypic screen for LRRK2 inhibitors

Colonization, inflammation and infection on Portuguese cystic fibrosis patients

Synthesis of Flavonoids with Antitumoral Activity

Elucidation of ceramide-induced apoptosis: modulation of Protein Kinase C isoforms

Evaluation of the biological activity of Bial compounds: modulation of different protein kinase C (PKC) isoforms, effects on the growth and cell death

Using yeast-based functional assays for the study of p53 signaling pathway, pharmacological screening and molecular characterization of small-molecules targeting p53 function

Study of the mechanisms of regulation of the tumour suppressor p53 protein by the isoform delta of protein kinase C (PKC): Using yeast as a cell model