PAGE 2015 - Crete, Greece

Wojciech Krzyzanski, PhD, MA. Associate Professor at Department of Pharmaceutical Sciences,

University at Buffalo. Holds PhD in applied mathematics and MA in pharmacology. Research focus

on pharmacokinetics and pharmacodynamics of hematopoietic growth factors and pharmacometrics.

Gilbert Koch, PhD. Gilbert Koch holds a PhD in applied mathematics. He worked as Postdoctoral

Associate at the Department of Pharmaceutical Sciences, University at Buffalo and recently joined the

Pediatric Pharmacology Group at the University Children´s Hospital in Basel as Research Assistant.

His research focus is on delay/lifespan modeling, anti-cancer effects in combination therapy and

modeling in pediatric drug development and rare diseases.

Johannes Schropp, PhD. Professor at Department of Mathematics and Statistics, University of

Konstanz. Research focus on PK/PD modeling and numerics of dynamical systems.

Matthias Machacek, PhD. Matthias Machacek studied mechanical engineering and obtained his

PhD from ETH Zurich for his research on fluid dynamics and computer vision. During his postdoc at

Scripps he applied computer vision to monitor molecules inside live cells at nanometer scale.

His research was published in both Nature and Science. After, Matthias established the Medical

Engineering Group at Novartis, dedicated to the systems pharmacology support for the preclinical

and translational development of biotherapeutics.Today, Machacek applies systems pharmacology

for the development of biologics and cell based therapeutics. He is Managing Director of LYO-X and

contributes to compound design, format selection, candidate selection, PK/PD and toxicology study

design, first in human dose selection, optimal dose-regimen finding and pediatric development. He also

works with Lixoft as a pharmacometrics expert developing and promoting the Monolix software suite.