R2011-2012

Research Projects 2011-2012

By

Abdalrhman M. Alhaj

Khalid H. Shorab

Awareness of University Students of Thalassemia Disease

Thalassemia illnesses are common and costly problem that cause significant morbidity and mortality worldwide in children and adult. In Palestine, thalassemia is one of the major causes of much blood disease. A questionnaire was constructed to collect data through both close and open ended questions. The questionnaire was reviewed and approved by the research supervisor. An Arabic translation version was made. The questionnaire included personal and socioeconomical data along with questions testing the knowledge about thalassemia.

Objectives

The main objective of this study is to assess the awareness among university students about Thalassemia in general.

Risk factors associated with chronic Kidney disease patients

Introduction

Chronic kidney disease(CKD)has now emerged as a major public health problem. Whereas it is associated with increased risk for end-stage renal disease (ESRD) when the damage is severe, it is being increasingly recognized that even when the damage is mild, CKD is a marker of increased cardiovascular risk.

General objective

To assess risk factors associated with Chronic Kidney Diseases in Gaza strip.

Specific objectives:-

1- To improve identification of risk factor that lead to CKD and increase public awareness about these risk factors.

2- Provide information about Risk factors which could help in earlier identification of CKD which would improve the outcome and prevention of CKD.

Urogenital Infection among Women in Gaza City

General objective

To determine genital infection in women

Specific Objective:

  1. Determine most common bacteria and fungi that causes urogenital infection
  2. Determine the Antimicrobial susceptibility of bacterial isolates.
  3. Determine the risk factors associated with urogenital infection
  4. Determine the sensitivity of A.F. genital system as compared with Routine cultures.

Alaa M. Khudeir

Islam F. Hassouna

Safaa M. Hassouna

Reem J. Esleem

Supervisor

Dr. Ahmad Sh. Silmi

By

Abedallh Hani alqutati

Karam Salah shubair

Supervisor

Dr. Atef Masad

Shereen Shallah

Asma EL kahlout

Aya Abu zour

Suher Islem

Supervisor

Dr. Abdelraouf A. Elmanama

The Effects of Oral Contraceptives and Intrauterine Devices on the Level of Some Biochemical and Hematological Parameters among Palestinian Women in Gaza city

General objective:

To assess the effect of contraceptives on the healthy status of Palestinian women in Gaza city by comparing oral contraceptives and intrauterine devices effects on different biochemical and hematological parameters.

Specific objectives:

1- To determine the level of sugar, cholesterol, triglyceride, HDL and LDL in blood samples collected cases compared with age matched cases.

2- To investigate the hematological parameters and iron level in cases and age matched control.

3- To make a comparison between the oral contraceptives and intrauterine devices according to their effect on different parameters

4- To determine the advantages and disadvantages of each method and to determine the more safe method for use

Ayat Hussein AL-Rantisy

Reham Safe AL-Hayya

Suhar Atef ELiwa

Hanan Ibrahim Abuo Hasera

Supervisor:-

Dr : Atef Masad

Isolation of Antibiotic producing bacteria from insects

OBJECTIVE:

Isolation of bacteria from gut of insect living in bird dropping.

Study effect of these bacteria to other bacteria.

Aliaa Madi

Abeer Alsafien

Supervisor

Dr. Abdelraouf A. Elmanama

Identification of navel normal microbiota

General objective

1. To detect and identify bacteria in swaps taken from navel.

2. To compare the results of overweight and thin people, children and adults.

3. hygiene to control such flora is important in preventing the transmission of antibiotic resistant hospital_aquired infections

So, in our research, we are going to educate people about the importance of paying attention of there hygien

Significance

There is no published data on the normal microbiota of the navel in gaza strip. This research will provide original and first time data on the types and numbers of Navel microbiota of Palestinians. This data may prove helpful in understanding transmission of diseases from endogenous sources.

By:

Mohammed eissa and ali totah

Supervised by

Dr. Abdelraouf A. Elmanama

The use of natural ph indicators in developing differential media

1.2 Objective

1.2.1 General objective :

How can we use simple materials found in our daily lives to be detectors of acid or base and apply these detectors in clinical microbiology laboratory

1.2.2 specific objective :

1- Comparing between the different microorganism depending of the produce color.

2- To develop new media in simple and easy ways.

3- To apply the new media in determining the characteristic of some microorganism.

Nour jamal hamadah

Amal darabaih

Supervisor

Dr. Abdelraouf A. Elmanama

Risk factor associated with breast cancer among woman in Gaza strip palestine

Our goal is to increase the awareness of Gazan women of the early symptoms of breast cancer and the importance of seeking medical care at first notice of symptoms and dterminethe important risk factors lead to tis cancer

Ansam Felfel

Shahinaz Elramlaouy

Madleen Banar

Supervised by

Antimicrobial Activity of Two Diatom (Microalgae) Species Isolated from the Coast of Gaza, Palestine

The objective

-To assess the antimicrobial activities of extracts of two marine diatom species; Amphora sp. and Cylindrotheca sp. against clinically important bacteria.

-explore the anti microbial ingredient s of amphora algae.

-investigate the synergistic effect of amphora extract with other anti biotic showing resistance toward target bacteria.

The significance

natural products which show anti bacterial action may have little toxic effect than the routinely used antibiotic.

-synergistic effect if any will probably reduced the dose of commercially available anti biotic.

Supervisor

Dr. Abdelraouf A. Elmanama

Dr. Kamal Elnabris

The effect of siwak against chromogenic bacteria and dental caries.

Bright white teeth are highly regarded and sought after in today’s society. Consumers invest a lot of money on cosmetic dentistry and in commercial products that promise an aesthetically pleasing smile. It follows that consumers should want to avoid or limit exposure to materials that contribute to the discoloration of teeth.

There has been a recent increase in interest in the treatment of tooth staining and discoloration as shown by the large number of tooth whitening agents appearing on the market. Some of these agents are sold as 'over-the-counter' products and have no professional involvement in their application.

Application of antibiotics for prevention and treatment of dental caries would be harmful for the patients and the development of multidrug-resistant (MDR) strains of bacteria is also possible

Aims: the aim of this study was to assess the antimicrobial activity of the miswak chewing stick (Salvadora persica) on Actinomyces and S. mutans

ياسمين سالم حرارة

عبير شفيق قنديل

غدير فؤاد كحيل

منة الله جاد الله البنا

By

May W. Shaheen

Rana KH. Aljarosha

Supervisor

Dr. Abdelraouf A. Elmanama

Associate Prof. (Microbiology)

Incidence of Urinary Tract Infection among Primary School Children in Gaza City

This research aims at determining the incidence of UTI among school children (ages between 6 to 12 years), and to determine causative agents. In addition, the antimicrobial susceptibility of the bacterial isolates will be assessed. Specimen collected from school children will be subjected to routine urine analysis, microscopic examination and culture. A questionnaire will be filled by parents or guardians in an attempt to determine possible risk factors associated with UTI. The samplse will be collected from six different schools from east and west of Gaza city .

مها ابو أمونه

كفاية أبو ركاب

أسماء قديح

Supervised by :

الدكتور: عبدالرؤوف المناعمة

الدكتور: عبد القادر العطل

The effect of dates on bacteria toxin

Proven effective dates in many aspects of medical including its ability to rid the body of toxins and we have chosen in this research study the effect of dates on the bacteria in terms of its effectiveness and its ability to get rid of the poison without damaging the object and the search is derived from the hadeeth of the prophet peace be upon him from becoming seven dates doesn’t matter on that day and the magic .

* Objective:-

Examine the effect of dates on neutralization of endotoxin produced by gram negative pathogens

bacteria and enviromental toxins exit every where around us and this way of simple ways to prevent .

Find the meanings of hadeeth and prove it scientifically.

research on mice and dividing the experiment into three stages in each phase of two groups the first group will be fed dates and other other food will then be injected groups poison and expected results are affected by the rats that did not deals with dates in second stage will be injected bacteria antibiotic after being injected with poison .

By

Sendrella El-Borno

Marwa Othman

Sally Abu Shabaan

Zaina Shubair

Antibiogram of most common bacteria causing wound infection among patients attending Al-Shifa hospital

Wound infections develop when bacteria gets into the wound and attaches to the tissue, thus the bacteria will grow and keeps the wound from healing. The bacteria may already be on the skin or it may simply be in the environment. When the skin is broken up by a cut or an open blister then a wound infection will most likely begin. This makes it very difficult for the wound to heal properly and the infection may actually spread to other parts of the body and create even more problems. This research is undertaken to identify the most common bacterial species that cause infectious diseases in Al-shifa hospital.

General objective

To identify the most common bacterial species isolated from wound infection and their susceptibility to available antibiotics in Al-shifa hospital.

Significances

-To clarify the effect of drug abuse which leads to increased multi drug resistant strains.

-To help in optimizing the use of antibiotics in treatment of woud infection.

-To minimize the multi drug resistant strains by using the suitable antibiotics based on culture and sensitivity test.

Amal Skeik

Rahma Aldahdouh

Supervisor

Dr. Abdelraouf A. Elmanama

The response of women with hemophilia to heparin treatment in the Gaza Strip

Thrombophilia is characterized by clinical tendency to thrombosis .The predispositionto form clots can arise from genetic factor, acquired changes in the clotting mechanism,.the most important of the inheritef thrombophilia are factor Vgen mutation G1691A,prothrombin G20210.Adelicate balance between coagulant and anticoagulant factors is needed to achieve a successful pregnancy.The hypercoagulable state that pregnancy association with a thrombophilic condition may be detrimental through either repeated pregnancy loss(RPL),intrauterine fetal death(IUFD).

Possible the results:

Likelihood of success of heparin-as anticoagulant in a number of women have the same genotype and the occurrence of pregnancy And the potential lack of success of heparin in a greater number of women with the knowledge that the study of women who have the same genotype..And so preventing possible to give some patients heparin (who did not benefit from it) and also prevent the damage that can be caused by heparin useless in these cases.

Research in general:

The genetic thrombophilia and pregnant women, who because of repeated abortion. And to study the six genes that have a particular Factor 5 and prothrombin , and Why do women with the same genotype their response to different heparin ,In other words, one carrying and the other does not carry?

By

Hosam S. Mizyed

Supervisor

supervisor:

Prof. Dr. Fadel asherif

Retrospective Study on Incidence and Risk Factors of Meningitis in Gaza Strip from 2000-2010

Meningitis is the inflammation of meninges, the membranes that cover the brain and spinal cord . Bacterial meningitis is still a major public health threat inside developing countries. Despite the widespread use of an attenuated live vaccine and several antibiotics, thereis more Meningitis than ever before, requiring new vaccines, drugs, more specific and rapid diagnostics(CDC ). The aim of this study was to provide a comprehensive and up-to-date assessment of Meningitis incidence rates from 2000-2010 in Gaza Strip and to determine the frequency distribution of different demographic factors (gender, age, type of patient, type of Meningitis, and province) and to assess the relationship of (age with type of Meningitis) and (age with gender) with developing of Meningitis disease. In view of increasing incidence of global Meningitis, and while numerous studies have been reported about Meningitis and its incidence, prevalence in over the world. To date there is no scientific, available research in Gaza Strip has been assessed. So, this kind of study could generate more information about Gaza Strip status from global Meningitis.

By

Amany A. Saeed

Falasteen F. Attallah

Eman A. Ahamed

May M. El-yazje

Abdelraouf A. Elmanama (Ph.D)

Ass.Prof. (Medical Microbiology)

New technique for venous blood collection

Most errors affecting laboratory test results occur in the preanalytical phase, primarily because of the difficulty in achieving standardized procedures for sample collection. This new technique will simplify tasks in laboratory diagnostics and improve the accuracy and precision of test results. This is means no more multiple needles prick to find a vein so that will be helpful for children and patients

Aim

Development of new technique for venous blood collection

Method: A sensor will be used in conjunction with a pressure cuff to determine the most appropriate pressure to visualize the vei

Expected Result

A more comfortable, positive experience for patients. Reduced costs due to fewer wasted consumables, more efficient use of personnel resources, and no lost time.

The Effect of Saffron and Ginger Extracts on Acute Lymphocytic Leukemic Cells

General Objective

To assess the apoptotic and the antiproliferative effect of Ginger and Safaron on acute lymphocytic leukemia cells in a primary cell culture.

Specific Objectives:

1. To isolate patients ALL cells in the laboratory that may be used in toxicity experiments.

2. To measure the apoptotic and the anti-proliferative effect of Ginger and Saffron extracts against ALL cell lines in the laboratory.

Supervisor

Dr. Abdelraouf A. Elmanama

The Effect of Saffron and Ginger Extracts on Acute Lymphocytic Leukemic Cells

Supervisor

Dr. Atef Masad

Researcher

Rola abu Eyada

Areej abu Jyab

Hadeel Hajaj

Samar Faadel