Advanced Microbiology


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Lecture Syllabus 

Microbiology impinges on almost every aspect of human life. This module forms a solid foundation for students who intend to pursue Microbiology at a higher level and provides a broad insight into the discipline for students studying Microbiology as a subsidiary subject in the first year.  

 InstructorDr. Abdelraouf A. Elmanama e-mail: elmanama@mail.iugaza.edu      

 

 Textbook: (The following book is required for all students) 

 

 Microbiology: An Introduction. 7th . Ed.  Tortora. Funke. Case (2002).  Addison Wesley Publishers 

  

  

  

Course Goals:  

1.     Define and use microbiological terms. 

2.     Describe the principles applied in culturing and characterizing microorganisms. 

3.     Distinguish diverse microorganisms according to their physiological characteristic. 

4.     Explain the role of microbes in human life. 

5.     Develop an awareness of the impact that microbes have on the biosphere and humans. 

6.     Describe the role of microbiology in biotechnology. 

7.     Demonstrate acquisition of general knowledge about microorganisms and the ability to utilize and apply this information. 

8.     Demonstrate skills necessary to perform laboratory investigations of microorganisms. 

9.     Communicate scientific findings to peers. 

10.   Read and understand scientific literature pertaining to Microbiology. 

11.   Understand the relationship that exists among microbes, man, and disease 

12.   Understand the environmental factors relating to microbial growth and control. 

13.   Appreciate the importance of microorganisms in our world in both beneficial and harmful ways. 

14.   Understand how microorganisms are harnessed for industrial and environmental uses. 

15.   Demonstrate understanding of the multitude of organisms classified as microorganisms. 

 

Examinations and Grading:   

Two major exams  

  • Midterm: 30 points  
  • Final:        40 points  
Microbe report: 5 points 

Main Presentation:  25 points  

  •             Report:             15  
  •             Presentation: 10  
Microbe of the Week    

Each student will be responsible for choosing a “Microbe of the Week”.  This will be part of your class participation grade.  Each student is asked to select a BACTERIUM and write a 5-10 page report describing that organism and its characteristic features.  You are asked to be creative and select unusual or little known organisms.  The “Microbes of the Week” will be dealt with in 2 parts.    

1) Oral presentation (2.5 points) – Give a brief description of your organism to the class. This should include a physical description, description of what it does, where it is found, etc.  Provide any interesting historical background about the organism or what it does, perhaps how the organism was named.  Explain why you found that particular organism interesting.  PowerPoint presentations are NOT necessary, but if you choose to use PowerPoint you must bring it by the class on a CD.     

Main presentation: 

2) Written report (2.5 points) A 5-10 pages written report will be due at the time of your in-class presentation.  Reference all sources, including web pages. You will need to submit an electronic version of your report.  Be creative.  Tell a story about the organism.  Write about how it was discovered, how it is used, who discovered it.  There are a number of books available for reading more about interesting microbes. 

 list of topic will be found at the end of this course description. Each student will be assigned one title to work on. The purpose of this assignment is to strengthen the student ability of information collection from various sources and broaden the knowledge gained in this course. You should deal with this assignment seriously as it may serve as a basis of thesis selection. You will be given a paper or an article as a start and then you will be on your own. References used should be cited properly using the system of the Islamic University Journal. 

Notes: 

No limit to page numbers.

Presentation Time: 20 minutes Discussion time: 10 minutes. Class participation is required. It would be fair to hand a copy of your report to each student a week before your presentation. 


 Lecture Topics.  You will be expected to have read the appropriate material prior to the coverage of each topic.  All material in the book may not be covered in lecture but you will be responsible for having read all the material.     

   

The following list of lecture topics is a guideline and is subject to change. 

  

PART ONE  

Fundamentals of Microbiology  

Chapter 1  

The Microbial World and You  

Chapter 2  

Chemical Principles  

Chapter 3  

Observing Microorganisms Through a Microscope  

Chapter 4  

Functional Anatomy of Prokaryotic and Eukaryotic Cells  

Chapter 5  

Microbial metabolism  

Chapter 6  

Microbial Growth  

Chapter 7  

The Control of microbial growth  

Chapter 8  

Microbial genetics  

Chapter 9  

Biotechnology and Recombinant DNA  

PART TWO  

A Survey of the Microbial World  

Chapter 10  

Classification of Microorganisms  

Chapter 11  

The Prokaryotes: Domains Bacteria and Archaea  

Chapter 12  

The Eukaryotes: Fungi, Algae, Protozoa, and Helminths.  

Chapter 13  

Viruses, Viroids and Prions  

PART THREE  

Interaction Between Microbe and Host  

Chapter 14  

Principles of Disease and Epidemiology  

Chapter 15  

Microbial Mechanisms of Pathogenicity  

Chapter 16  

Nonspecific Defenses of the Host  

Chapter 17  

Specific Defenses f the Host: The Immune Response  

Chapter 18  

Practical Application of Immunology  

Chapter 19  

Disorders Associated with the immune system  

Chapter 20  

Antimicrobial Drugs  

PART FOUR  

Microorganisms and Human Disease  

Chapter 21   

Microbial Diseases of the Skin and Eye  

Chapter 22  

Microbial Diseases of the Nervous System  

Chapter 23  

Microbial Diseases of the Cardiovascular and Lymphatic System  

Chapter 24  

Microbial Diseases of the Respiratory System  

Chapter 25  

Microbial Diseases of the Digestive System  

Chapter 26  

Microbial Diseases of the Urinary and Reproductive System  

PART FIVE  

Environmental and Applied Microbiology  

Chapter 27  

Environmental Microbiology  

Chapter 28  

Applied and Industrial Microbiology  

 


Internet resources 

  

http://www.mansfield.ohio-state.edu/~sabedon/biol4045.htm  

  

Main Presentation T (suggested titles)

 

§  The involvement of microorganisms in symbioses.

§  A comparison of chemical and biological techniques for the control of pests.

§  Fungi and Man.

§  Compare and contrast the modes of life of parasitic fungi with those of saprophytic fungi.

§  The eradication of pathogenic microorganisms – an admirable goal or a reduction in biodiversity?

§  Simplicity equals success – why are prokaryotic microorganisms so good at evolution?

§  Antibiotic resistance.

§  Industrial microbiology.

§  The application of PCR and Southern Blotting to medical microbiology.

§  Hospital acquired infections.

§  The variability in nutrition of prokaryotes may be explained by the variability of nutrient transport by different cells.

§  The macrophage.

§  Immunization against infectious disease.

§  Discuss the host response to infection. Outline those immunological tests used to diagnose infection.

§  Antibiotics – their production and use.

§  “Microbes make the world go round” – Discuss the role of microbes in the cycling of elements.

§  Photosynthetic prokaryotes

§  Discuss the virulence-factors of bacteria that cause disease.

  

Note: You can select any title outside the above list provided you get my approval

 

Best wishes

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