You can check out our poster and presentation we used to compete at these fairs here!
Cannabidoil (CBD) and CBD-infused products (Pic. 1) are being increasingly sold around the US, and these products have the potential to treat many different diseases such as Parkinson's, Alzheimers, schizophrenia, depression, obesity and many more. But little is known about how CBD affects the body and how it interacts with the many receptors inside the body in order to cause these great benefits. Therefore more research must be done in order to utilize this substance.
In our research, we will determine if CBD can bind to receptor systems such as Serotonin, Adenosine, and Peroxisome Proliferator-activated receptors (PPARs) thus allowing us to determine if D. melanogaster (Pic. 2) are a good model organism to study CBD's effects on the body. We will do this by inducing anxiety in flies and measuring their wall-following behavior as an indication of CBD's effectiveness. To fund our research, we needed $65, and now we're fully funded! This money will be used to purchase the D. melanogaster, square petri plates, and CBD necessary for this project.
We will be mentored by Laura George, a Molecular biology PhD graduate University of Colorado, Anshutz. Currently, she is using fruit flies to study development at the University of Colorado Anschutz Medical Campus. Our other mentor is Brenna Dennison, a Biology graduate student at the University of Colorado, Denver. Currently, she is doing research on receptor tyrosine kinase signaling in mammalian craniofacial development at the Fantauzzo Lab. Additionally, we will be mentored Kezia D., Shreya N., and Calli P. who are previous RCHS research students (see their website here).