Cytomegaly is the enlargement of the cytoplasm and in this case, is caused by cytomegalovirus.
Nuclear inclusion is the growth of unusual proteins/nucleic acids that aggregate around the nucleus.
Intranuclear Inclusions. (2023). MyPathologyReport, https://www.mypathologyreport.ca/pathology-dictionary/intranuclear-inclusions/
Cedeno-Mendoza, R. et al. (2024). Cytomegalovirus (CMV). MedScape, https://emedicine.medscape.com/article/215702-overview?form=fpf
Intranuclear Inclusions. (2023). MyPathologyReport, https://www.mypathologyreport.ca/pathology-dictionary/intranuclear-inclusions/
Mallory's Trichrome Stain. (n.d.) Taylor & Francis, https://taylorandfrancis.com/knowledge/Medicine_and_healthcare/Anatomy/Mallory%27s_trichrome_stain/
Saravanan, S., et al. (2015). Chapter 10 - Nonhuman Primate Diseases of Relevance in Drug Development and their Impact on the Interpretation of Study Findings. Academic Press, Pages 187-213,
ISBN 9780124171442, https://doi.org/10.1016/B978-0-12-417144-2.00010-X. (https://www.sciencedirect.com/science/article/pii/B978012417144200010X)
The potential hazards of the Mallory stain are dependent on which dyes are used to make up the stain. It is advisable to read the safety data sheets (SDS) of each reagent you are using. Reasonable lab safety is encouraged- wear lab goggles, gloves, and appropriate clothing.
Red:
Nuclei
Muscle
Orange:
Erythrocytes (red blood cells)
Blue:
Collagen
Bergman, R. A. et al. (n.d.) Plate 3.35: Elastic Membranes; Collagenous Fibers. https://www.anatomyatlases.org/MicroscopicAnatomy/Section03/Plate0335.shtml
Boric, K., Mardesic, S., Martinovic Kaliterna, D. et al. Expression of apoptotic and proliferation factors in gastric mucosa of patients with systemic sclerosis correlates with form of the disease. Sci Rep 9, 18461 (2019). https://doi.org/10.1038/s41598-019-54988-0
Krušlin, Božo & Ulamec, Monika & Tomas, Davor. (2015). Prostate cancer stroma: An important factor in cancer growth and progression. Bosnian Journal of Basic Medical Sciences. 15. 10.17305/bjbms.2015.449.
Elmelegy, Manal & El-Melegy, & Ghoneim, Nagwa & Mohamed, Nermeen & El-Dien, Noor & Rizk, Mohamed. (2019). Silver Nano Particles Improve the Therapeutic Effect of Mebendazole Treatment during the Muscular Phase of Experimental Trichinellosis. 10.7537/marsjas150519.06.