BxChip®

The BxChip® is a sectionable planar matrix* made from a biomimetic, organic polymer that allows the creation of tissue microarrays for routine clinical diagnostics at the point of care. The BxChip® virtually eliminates core fragmentation by protecting delicate tissue cores. And, it reduces the need for tissue manipulation. Parallel processing and sectioning of tissue cores significantly increase the yield of tissue on microslides, and, consequently, cancer detection rates.

Fresh biopsy samples can be loaded into the site-specific channels of the BxChip® in the Operating Room (sterile matrices, packaged in isotonic saline). Alternatively, pre-fixed biopsies that arrive in the Pathology Laboratory can be loaded in non-sterile matrices (packaged in formalin). 

*The matrix material does not interefere with IHC, ISH, FISH, NGS or other molecular testing methods. 

For a standard prostate biopsy, a minimum of 12 cores typically requires the preparation of 12 separate paraffin blocks.

The 12-channel BxChip® consolidates all biopsies into a single matrix, producing just one paraffin block and significantly reducing the number of slides required.

This approach greatly decreases the use of histology consumables—including standard plastic cassettes, biopsy pads, dehydrating and clearing solvents, glass slides, staining reagents, and coverslips.

In addition, the streamlined design shortens the time a technician spends on microtome sectioning.