Associate Professor
Ayumi Kyota
Department of Nursing, Graduate School of Health Sciences
The main focus of my research is to explore better communication between patients and nurses by examining the views of life and death of "terminal cancer patients" who are aware that their death is imminent.
I first became interested in this topic while working as a nurse at an acute care hospital. One terminal cancer patient said to me, "I think this is the last firework. Today is the anniversary of my mother's death." I was so struck by the words "last" and "anniversary of her death" that I could not reply to her. I regretted that if I had tried to listened to her more carefully, I might have been able to provide better nursing care that would have enabled her to live a life that was more like her own until the last moment of her life.
Even when I read articles and books, all I read was "respect the views of life and death of each person." I then went on to graduate school and began this research.
As a doctor, I am involved in pathology diagnostic work, while my research focuses on breast pathology and cancer. One of my research focuses on image analysis technology for pathological tissue using AI (artificial intelligence). I want to quantify the morphological features of colorectal cancer and find indicators (morphological biomarkers) that can predict treatment efficacy and prognosis.
Pathological diagnosis involves determining benign or malignant status and identifying histological types by annotation (labelling; see figure) of lesions (abnormal cells and tissues). In cancerous tissues, it also evaluates the malignancy of the cancer and determines the indications for drugs and the effectiveness of treatment.
Morphology is essential in the pathological diagnosis of cancer. This is because malignancy is determined by morphological features such as the appearance of the nucleus and nucleoli, the frequency of mitosis, the amount of necrosis and the mode of invasion. In recent years, lymphocytes/plasma cells spreading within the cancer tissue have gained attention as markers of drug therapy efficacy and related to prognosis.
Lecturer
Ayaka Katayama
Department of Diagnostic Pathology, Graduate School of Medicine
Organisational picture before annotation (left) and post-annotation image (right)
Assistant Professor
Yuta Sugiyama
Center for Food Science and Wellness
The gut microbiota is considered "another organ" because it affects the overall health of the host. However, many unexplored aspects exist of the host and intestinal bacteria interactions. I aim to elucidate this interaction at the genetic level of intestinal bacteria.
I became interested in intestinal bacteria when I was engaged in research on the mechanism of substance-mediated symbiosis between host and intestinal bacteria at the endowed chair of the Institute of Fermentation Research established at Ishikawa Prefectural University, which is what led me to devote myself to this research.