Associate Professor Koji Shibasaki has been researching to explore the relationship between brain function and diseases by focusing on the temperature sensor TRP, as he believes that the source of human intelligence is supported by the characteristic of maintaining a constant body temperature as a homeothermic animal. He also hypothesized that a constant temperature in the brain might be another factor contributing to human intelligence. Through his experiments, he discovered that the "temperature sensor TRPV4", which activates at 34℃, is highly expressed in the brain's nerve cells. He further determined that the continuous activation of TRPV4 at the brain's temperature of approximately 37℃ is crucial in facilitating the smooth operation of nerve cells. He became the first to elucidate the molecular mechanism that translates brain temperature as an information source and utilizes it in neural information transmission. In the fiscal year 2015, he launched a new field called "Temperature Biology" under the funding support of the Ministry of Education, Culture, Sports, Science and Technology's New Academic Field Research program. He aims to investigate further relationship between brain temperature and brain function at the molecular level, creating novel scientific and technological advancements from Japan.