small RNA Extraction in Exosome
Product Description
Exosomes are nano-sized vesicles released into the extracellular environment e.g. body fluids including plasma, urine, saliva, and amniotic fluid. Initial findings merely identified them as cellular waste or by-products of cell activities, having little significance in the field. It is only recently that exosomes were shown to carry complex cargo of genetic materials, allowing intercellular communication between various target tissues. This exciting finding led to implication of exosomes as potential non-invasive diagnostic biomarkers and therapeutic nanocarriers. Despite numerous approaches to exosome isolation and growing number of related studies, their role as diagnostic biomarkers of disease remain incompletely understood. Nevertheless, as exosomes represent a novel platform of next-generation diagnostic tool, there’s an urgent need for optimal exosome isolation technique to take our step towards improving human health.
Convenience
Faster RNA Purification
정량가능
회수율 높음
Product Performance
Exosomes were isolated from 100 μl of plasma using XENO-EVI. miRNAs were purified from Exosome pellets using XENO-EVARI kit and miRNA extraction kit of company A. The expression level was quantified by XENO-Q miRNA detection kit of XENOHELIX.
Exosomes were isolated from 100 μl of plasma using XENO-EVI. Exosomal RNA was extracted from plasma EV 1, 5, and 20 μl with EVARI kit, respectively. 200 ng of RNA were used to detect of hsa-miR-92a-3p, hsa-miR-210-3p by XENO-Q miRNA detection kit of XENOHELIX.