PHARMACOLOGY

I. BASIC PHARMACOLOGY (40%)

The scope of this subject includes the physiological effects of drugs and the mechanism of their actions.

SAMPLE QUESTIONS

1. What do you call the component of a pharmaceutical preparation which is responsible for its therapeutic effect?

a. Active ingredient

b. Adjuvant

c. Vehicle

d. Mediator

2. A 10% solution of sodium chloride contains:

a. 10 gm in 100 ml

b. 10 gm in 10 ml

c. 10 mg in 100 ml

d. 10 gm in 1000 ml

3. On which muscle tissues will acetylcholine evoke excitatory response?

a. Smooth muscles of the GI tract

b. Myocardium

c. Vascular smooth muscles

d. Atrioventricular node

4. How does atropine acts on the parasympathetic nervous system?

a. Competitive antagonism of acetylcholine

b. Depresses formation of acetylcholine

c. Enhances formation of cholinesterase

d. Stimulates adrenergic activity

5. Alpha-adrenergic receptors in the medullary part of the brain when stimulated will produce:

a. A decrease in blood pressure and bradycardia

b. An elevation of blood pressure and tachycardia

c. Vasoconstriction and bradycardia

d. A vasodilatation and tachycardia

II. CLINICAL PHARMACOLOGY (60%)

This topic covers the use and application of drugs for modification of functions and control of diseases of the various body systems. It also covers the drugs used for the treatment and control of a wide variety of infectious diseases. It also includes information on antibiotics, antivirals, insecticides and anthelmintics.

SAMPLE QUESTIONS

1. The following infections are correctly paired with effective antimicrobial therapy, except:

a. Tetanus - oxytetracyline

b. Salmonellosis – chloramphenicol

c. Ehrlichiosis - doxycycline

d. Mycoplasmosis - tylosin

2. If an animal patient has a history of penicillin allergy, which of the following anit-infectives is an appropriate replacement?

a. Erythromycin

b. Gentamicin

c. Doxycycline

d. Ciprofloxacin

3. Drug of choice for congestive heart failure:

a. Digitalis

b. Quinidine sulfate

c. Atropine

d.Procainamide hydrochloride

4. Chronic use of this therapeutic agent may cause vitamins A, D, E and K deficiency:

a. Mineral oil

b. Tetracycline

c. Chloramphenicol

d. Lincomycin

5. The following conditions or drugs have been correctly paired with their appropriate antidotes or specific remedies, except:

a. Halothane - epinephrine

b. Morphine overdose - naloxone

c. Xylazine overdose - yohimbine

d. Respiratory arrest during anesthesia - doxopram