Work of the Effort and the Work of the Load remain the same as shown in the equation below.
Work(in)=Work(out)
Work(Effort)=Work (Load)
Force(Effort) x Distance(Effort)=Force(Load) x Distance(Load)
If you had to move a force of 10,000 pounds a distance of 10 feet.
The amount of work would be 100,000 pound-feet.
This amount of force is impossible to move by one normal person unless using a simple machine.
Work(Effort)=Work(Load)
100,000 pounds-feet = 100,000 pounds-feet
50 pounds x 2000 feet= 10,000 pounds x 10 feet
In this a equation moving 50 pounds a distance of 2000 feet will allow you to move a 10,000 pound Load a distance of 10 feet using a simple machine.
You cannot change the amount of Work needed to be done, but simple machines allow you can change the amount of Force (Effort) and the Distance (Effort ) it travels to move a another Force (Load) it's distance to travel.