Electrophysiology recording using 2D or 3D Coreplate chip from 3Brain technology. Advantages of 3Brain technology:

• Label-free functional monitoring of whole organoids with single-cell spiking activity resolution.

• Improved statistical significance measuring from thousands of neurons simultaneously

• Multiple sample recordings: 3Brain’s single-well CorePlate™ has a sensing area of up to 25mm², allowing to record multiple spheroids in a single experiment. [price inquire]

Performed by and in collaboration with the Biomarkers Platform at Achucarro Basque Center for Neuroscience. Multiplex Beads Based Immunoassays or Single Molecule Array (SIMOA) [price inquire]

Performed by and in collaboration with the Imaging Facility at Achucarro Basque Center for Neuroscience. We can provide different options for cell and tissue histological analysis such as Leica TCS STED CW SP8 super-resolution, vertical Leica Stellaris 5 (DM6 B CS) confocal microscope, Femto-2D two-photon microscope.  [price inquire]

Performed in collaboration with the Cell Analytic Facility at Achucarro Basque Center for Neuroscience. Fluorimetric single cell analysis and cell sorting with BD FACSJazz (2B/4YG) cell sorter and analyser  [price inquire]

Performed in collaboration with the Molecular Biology Facility at Achucarro Basque Center for Neuroscience. We can test the efficency of your AAVs (serotypes 8 or 9) on our brain organoids. 

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