After 20 years or so had passed since the disappearance of the Roanoke colonists, England attempted it's second colony here in America: Jamestown, Virginia. Jamestown settlers suffered through some difficult years in the beginning but by 1620, they had established themselves as the 1st PERMANENT English colony here in America. Officials back in England asked the Jamestown colonists to set out on a mission to get answers to what may have happened to the Lost Colony of Roanoke.
After speaking with several native tribes in and around the Jamestown and Roanoke areas, the expedition's leader, Captain John Smith, concluded that the Roanoke colonists had probably been killed by the Powhatan Indian Chief who had bragged about the massacre. Other information that was gathered stated there was a massacre and that perhaps a few of the Roanoke colonists had survived. Later research however found that there were in fact two massacres led by the Powhatan Indians close to the Roanoke area but that they did not involve any of the white, Roanoke settlers. One thing is for certain: If the Roanoke settlers were still alive in 1620, they never attempted to reach out to their fellow Englishmen who were now also here in America at Jamestown. (Jamestown is located only a few hundred miles up the coast from Roanoke Island)