Wound Healing Potential of Onion (Alluim cepa L.)
Extract on White Mice
Wound Healing Potential of Onion (Alluim cepa L.)
Extract on White Mice
I would like to extend my earnest appreciation to those who, in any way, contributed to the success in the handling of this study.
To Dr. Christy Kae N. Selfa and Dr. Christian Ed Alera, for guiding me throughout every step of this research and for lending their knowledge from their profession and expertise in the study.
To our research adviser, Mrs. Kristine C. Sinfuego, for her continuous support and patience, and partaking her profession from the very first steps of this research until the end.
To my STEM family, for giving me the constant sense of hope, ease and fellowship amidst all pressure and stress.
To my dearest father Mr. Retchie H. Porcadilla and loving mother, Ms. Jerelyn S. Porcadilla, for their steady financial, emotional, and moral support that made this research conceivable.
And to those who aren’t mentioned, but have contributed to the accomplishment of this study.
Above all, to God Almighty, the outmost source of my motivation, strength, and achievement. For the never ending shower of blessings and provided wisdom and patience throughout the journey in making this research. Without him, this research would not be possible.
I dedicate this research to my beloved sister, Miss. Assyra S. Porcadilla, the reason for determination throughout the process of this study, to the future researchers who would explore further into this topic, and most especially to God Almighty.
Skin is the largest organ in the body and covers the body's entire external surface and our first line of defense against impurities and other harmful factors. But often enough, our skin gets harmed and wounded and can cause to lead to more complicated instances when left untreated. The purpose of this study was to determine the potential and effectivity of Onion to provide wound healing. This study used purposive sampling. Sixteen adult either sex white mice were assigned randomly and equally to five treatments. Each replicate received the product with their assigned proportions of onion extract Treatment 0 replicates received the product with 0% Onion extract and 100% distilled water, Treatment 1 replicates with 100% Onion extract and 0% distilled water, Treatment 2 replicates with 25% Onion extract and 75% distilled, Treatment 3 replicates with 50% Onion extract and 50% distilled water, and Treatment 4 replicates with 75% Onion extract and 25% distilled water. Treatment 0 was the control group and only received distilled water to determine its difference with the other treatments. Specimens were given treatment and was observed everyday up to 15 days. Specimens’ wound status were rated everyday according to rating rules. Mean scores of replicates were computed every day to determine their healing rates. As results, Treatment 3 possessed the fastest healing rate among the treatments with a mean score of 5 for days 14 and 15, followed by Treatment 2 with a mean score of 5 on day 15. Treatment 1 received a mean score of 4 and Treatment 0 received a mean score of 3.33 on day 15. In conclusion, Onion extract contain significant wound healing properties and moreover more effective when the onion has a longer shelf life.
AIRA S. PORCADILLA
GRADE 12 STEM STUDENT
Currently enrolled at St. Lorenzo School of Polomolok, INC.