Publications

Qiu K, Vu D, Wang L, Bookstaver A, Dinh TN, Goldfarb AN, Tenen DG, Trinh BQ.  Chromatin structure and 3D architecture define differential functions of PU.1 cis regulatory elements in human blood cell lineages. BioRxiv, 2024, under revision  

Korczmar E*, Bookstaver A*, Ober E, Goldfarb A, Tenen DG, Trinh BQ. Regulating expression of the lineage gene PU.1 in normal development and diseases: the role of cis-regulatory elements. Front Biosci, 2024 

Ebralidze AK, Umarino S, Bassal MA, Zhang H, Budnik, B, Monteleone E, Kappei D, Liu YV, Tenen DE, Coffey R, Sheen MR, Zhang Y, Wanet A, Trinh BQ, Poli V, Angarica VE, Magallanes RT, Benoukraf T, Crane-Robinson C, Di Ruscio A, Tenen DG. Formation and recycling of an active epigenetic mark mediated by cell cycle-specific RNAs. BioRxiv, undereview  

Umarino S, Ebralidze AK, Monteleone E, Zhang Y, Trinh BQ, Di Ruscio A, Tenen DG. S-phase induced RNAs initiate formation of DNA replication origin. BioRxiv, under review  

Coffey R, Tenen DG, Trinh BQ. RUNX1 as an RNA-binding transcription factor in blood cell development and diseases. Gene Expression Omnibus. Accession: GSE244530. 2023

Zhao X, Bartholdy B, Yamamoto Y, Evans EK, Alberich-Jordà M, Staber P, Benoukraf T, Zhang P, Zhang J, Trinh BQ, Crispino JD, Hoang T, Bassal MA, Tenen DG. PU.1 - c-Jun interaction is crucial for PU.1 function in myeloid development. Communications Biology. 2022, PMID: 36104445.

Trinh BQ*, Ummarino S, Zhang Y, Ebralidze AK, Bassal MA, Nguyen TM, Heller G, Coffey R, Tenen DE, van der Kouwe E, Fabiani E, Gurnari C, Wu CS, Angarica VE, Yang H, Chen S, Zhang H, Thurm AR, Marchi F, Levantini E, Staber PB, Zhang P, Voso TM, Pandolfi PP, Kobayashi SS, Chai L, Di Ruscio A & Tenen DG*. Myeloid lncRNA LOUP Mediates Opposing Regulatory Effects of RUNX1 and RUNX1-ETO in t(8;21) AML. Blood Journal. 2021. PMID: 33971010 (*corresponding authors). Editorial commentary. Learn more

van der Kouwe E, Heller G, Czibere A, Agreiter C, Castilla LH, Delwel R, Di Ruscio A, Ebralidze AK, Forte M, Grebien F, Heyes E, Kazianka L, Klinger J, Kornauth C, Le T, Lind K, Barbosa MA, Pemovska T, Pichler A, Pulikkan JA, Schmolke AS, Schweicker C, Sill H, Sperr W, Spittler A, Surapally S, Trinh BQ, Valent P, Vanura K, Welner RS, Zuber J, Tenen DG, Staber BP. Core binding factor leukemias hijack T-cell prone PU.1 antisense promoter. Blood Journal. 2021. PMID: 34010414. Editorial commentary. Learn more

Umarino S, Hausman C, Gaggi G, Rinaldi L, Bassal MA, Zhang Y, Seelam AJ, Kobayashi IS, Borchiellini M, Ebralidze AK, Ghinassi B, Trinh BQ, Kobayashi SS, Di Ruscio A. NAD modulates DNA methylation and cell differentiation. Cells. 2021. PMID: 34831209

Trinh BQ, Tenen DG. Compositions and methods for targeting tumor associated transcription factors. US Patent Application Number: 63/054,531. 2020, read more

Trinh BQ, Coffey R, Bassal M, Tenen DG. Transcriptome-wide survey of Runx1-interacting RNAs by RNA immunoprecipitation sequencing. Gene Expression Omnibus. Accession: GSE140459. 2019

Trinh BQ, Barengo N, Kim SB, Lee JS, Naora H. The homeobox gene DLX4 regulates erythro-megakaryocytic differentiation by stimulating IL-1b and NF-kB signaling. Journal of Cell Science 128(16):3055-67. 2015. PMID: 26208636

Trinh BQ, Ko SY, Haria D, Barengo N, & Naora H. The homeoprotein DLX4 controls ovarian tumor angiogenesis by regulating expression of inducible nitric oxide synthase. Molecular Cancer. Apr 30;14(1):97. 2015. PMID: 25924901

Haria D*, Trinh BQ*, Ko SY, Barengo N, Liu JS & Naora H. The homeoprotein DLX4 stimulates NF-κB activation and CD44-mediated tumor-mesothelial cell interactions in ovarian cancer. American Journal of Pathology 185(8):2298-308. 2015. PMID: 26067154 (*equal contribution)

Trinh BQ, Naora H. Gene expression changes induced in K562 cells by the homeobox gene DLX4 and by treatment with Activin A and phorbol 12-myristate 13-acetate. Gene Expression Omnibus. Accession: GSE63888. 2014

Trinh BQ, Ko SY, Barengo N, Lin SY, Naora H. Dual functions of the homeoprotein DLX4 in modulating responsiveness of tumor cells to topoisomerase II-targeting drugs. Cancer Research 73:1000-10. 2013.  PMID: 23222298

Trinh BQ, Naora H. Homeobox genes and theirs functional significance in ovarian tumorigenesis, Ovarian Cancer / Book 1, ISBN 978-953-307-812-0, 2012

Trinh BQ, Barengo N, Naora H. Homeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-b cytostatic program and blocks the anti-proliferative effect of TGF-b. Oncogene 30: 2718-2729. 2011.  PMID: 21297662

Xie X, Hsu JL, Choi MG, Xia W, Yamaguchi H, Chen CT, Trinh BQ, Lu Z, Ueno NT, Wolf JK, Bast RC Jr, Hung MC. A novel hTERT promoter-driven E1A therapeutic for ovarian cancer. Molecular Cancer Therapeutics Aug;8(8):2375-82. 2009. PMID: 19671744

Trinh BQ, Truong NU, Truong TT, Le QTM, Nguyen HTH and Dinh KD. Cloning and expression of the genes encoding PreM and Envelope proteins of of Dengue virus type 4. Access No:  AJ563356, 2003. Development of the diagnostic kit using this recombinant protein was in the Vietnam national media, "Development of the diagnostic Kit for rapid detection of Dengue virus", VietNamNet, 2006

Vu B, Nguyen DK, Trinh BQ, Bach Q, Dinh KD, Dinh VT. Detection and quantification of yellow head virus load in shrimp using Real-Time PCR with SYBR Green. Journal of Science (Hanoi National University). 21(2): 59-65. 2005

Le C, Dai BD, Hoang CM, Nguyen VV, Le DT, Dinh KD, Bach Q, Trinh BQ, Duong QH, Nguyen HH, Nguyen DT, Nguyen DB. Detection of BRCA1 and BRCA2 mutations in breast cancer patients by Real-Time PCR. Proceeding of the National Conference on Basic Research. Institute of Military Medicine. 372-376. October 28, 2004

Trinh BQ, Nguyen BH, Truong NU, Le M, Nguyen H, Dinh KD. 2003. Cloning and expression the region encoding Premembrane and envelope proteins of dengue virus type 4. Journal of Biotechnology 1(1): 33-38. 2003

Ha QT, Trinh BQ, Bach QTN, Phung CD, Do KN and Dinh KD. Cloning of the gene coding for enterotoxin subunit A from Vibrio cholerae serotype Inaba. Access No:  AJ575590, 2003

Ghazi AK, Trinh BQ, Truong DV and Dinh KD. Cloning and expression of the gene encoding VP2 protein of Infectious Bursal Disease virus. Access No: AJ577092, 2003

Bui HT, Vu HT, Le HL, Trinh BQ, Nguyen MT, Bach QTN, Nguyen CT, Dinh KD. Cloning of the gene coding for homoserine acetyltransferase from Corynebacterium glutamicum isolate TK3600. EMBL/GenBank/DDBJ databases. Access No: AJ584663, 2003