Bon Trinh
Principal Investigator
415 Lane Rd. P.O. Box. 800904
Charlottesville, VA 22908-0904, USA
bontrinh@virginia.edu
Bon Q. Trinh, PhD
Principal Investigator, University of Virginia
Dr. Trinh is a tenure-track Assistant Professor in the Department of Pathology at the University of Virginia (UVA) and a faculty member of both the Molecular Genetics & Epigenetics Program at the UVA Comprehensive Cancer Center and the UVA Center for RNA Science and Medicine. Prior to joining UVA, he served as an Instructor of Medicine at Harvard Medical School and as a staff scientist at Beth Israel Deaconess Medical Center. He has extensive research experience in gene regulation during development and cancer, including normal blood development, cancer cell proliferation, drug resistance, tumor angiogenesis, and metastasis. His research models include hematologic, gynecological, and breast malignancies.
Dr. Trinh’s current research employs an interdisciplinary approach that spans biochemistry, molecular and cellular biology, as well as genome-wide bioinformatics, cheminformatics, and statistical analyses. His studies utilize both normal and cancer cells, in addition to mouse models. His laboratory integrates experimental and computational methods to investigate how proteins and RNAs function at the chromatin level to regulate key genes involved in normal myeloid cell maturation, leukemia development, myeloid cell interactions with microbes and disease-affected cells, and drug response. The goals of this work are to identify actionable molecular targets and diagnostic biomarkers, and to develop innovative therapeutic strategies for diseases such as cancer.
Dr. Trinh has a track record of securing government and foundation funding to support his research. He is passionate about translating scientific discoveries to benefit patients and about training the next generation of life science researchers. Outside of his research activities, Dr. Trinh enjoys spending time outdoors with his wife and children, as well as learning computer languages for use in genome-wide analyses, molecular dynamics simulations, and technology transfer. Dr. Trinh is on LinkedIn, ResearchGate, BIMS, and UVA Pathology
Committee and mentoring (selected)
Dr. Trinh serves on recruitment/review/student advisory committees for Biomedical Sciences Graduate Program, Medical Scientist Training Program, and research staff at UVA, VEF2.0 program that select and mentor Vietnamese applicants for graduate studies at US universities, and postdoctoral program for Training Program for Strengthening Research Capacity in Non-Communicable Diseases in Vietnam (TSORC-NCDs-VN). He involved in Diversity and Advance Health Equity through Curricula Innovation at Harvard Medical School. He supervises and co-supervises students throughout his research career. Dr. Trinh received teaching certificates from National School of Education (Hanoi, Vietnam) and STEM Education Solutions.
Awards and Honors (selected)
2025- Guest Editor of Biology, Special issue on Regulation of Gene Expression in Immune Cell Development and Function
2025 Pediatric Cancer Research Foundation’s External Review Committee
2025 Special Emphasis Panel/Scientific Review Group 2025/05 ZRG1 BTC-J (02) M study section, National Institute of Health
2025 Pilot research award, UVACCC Cancer Therapeutics (CRX) Research Program
2025 Pilot research award, UVACCC Biostatistics Shared Resource (BSR)
2025 EIAP scholar, Early Investigator Advancement Program (EIAP), National Cancer Institute.
2024 Special Emphasis Panel/Scientific Review Group 2025/01 ZRG1 BTC-J (55) R study section, National Institute of Health
2024 R21 Exploratory/Developmental Research Grant, National Cancer Institute (NCI)
2024 Small Data Analytics Resource Award, UVA Data Analytics Center
2024 4-VA UVA Collaborative Research Grant
2024 Pilot research award, Hematologic Malignancies Translational Research Team, UVA Cancer Center
2023 Early Career Reviewer, Genomics, Computational Biology And Technologies (GCAT) study section, National Institute of Health
2023 Pilot research award, Center for Systems Analysis of Stress-Adapted Cancer Organelles and the UVACCC Biostatistics Shared Resource
2022 The American Cancer Society Institutional Research Grant
2022 DICP Faculty Fellowship, Harvard Medical School
2020 Research from Early Career Highlights (REACH) featuring studies of instructors and assistant professors, Beth Israel Deaconess Medical Center
2019 Team Award of pitch competition, Harvard Healthcare Innovation and Commercialization
2018 Annual Meeting Abstract Achievement Award, American Society of Hematology
2018-22 GRASP scholar, Harvard Catalyst
2017 K01 Mentored Research Scientist Development Award, National Cancer Institute
2017 F32 NRSA Individual Postdoctoral Fellowship, National Heart, Lung, and Blood Institute
Research mentoring programs (selected)
2023, 2025 Research mentor, Medical Student Summer Research Program (MSSRP)
2023, 2025 Research mentor, The School of Medicine’s Summer Opportunities in Academic Research (SOAR)
Courses taught (selected)
2023- Research mentor, UVA BIOL4910 Independent Research
2023 Instructor, BIMS 8993 Non-topical Research: Visiting Research Graduate Traineeship Program (VRGTP)
2022- Research mentor, UVA CHEM 3951 Undergraduate Research