Journal club

Recommended papers (?)

2024.2.9

Extracellular vesicles could be a putative posttranscriptional regulatory mechanism that shapes intracellular RNA levels in Plasmodium falciparum

Mwikali Kioko , Alena Pance, Shaban Mwangi, David Goulding, Alison Kemp, Martin Rono, Lynette Isabella Ochola-Oyier, Pete C Bull, Philip Bejon, Julian C Rayner, Abdirahman I Abdi

Nat Commun. 2023 Oct 13;14(1):6447.  doi: 10.1038/s41467-023-42103-x.

https://pubmed.ncbi.nlm.nih.gov/37833314/

Protein kinase PfPK2 mediated signalling is critical for host erythrocyte invasion by malaria parasite

Rahul Singh Rawat, Ankit Gupta, Neelam Antil, Sonika Bhatnagar, Monika Singh, Akanksha Rawat, T S Keshava Prasad , Pushkar Sharma

PLoS Pathog. 2023 Nov 21;19(11):e1011770.  doi: 10.1371/journal.ppat.1011770. eCollection 2023 Nov.

https://pubmed.ncbi.nlm.nih.gov/37988347/

2024.1.31 by Shinzawa

Delftia tsuruhatensis TC1 symbiont suppresses malaria transmission by anopheline mosquitoes

Wei Huang, Janneth Rodrigues, Etienne Bilgo, José R Tormo, Joseph D Challenger, Cristina De Cozar-Gallardo, Ignacio Pérez-Victoria, Fernando Reyes, Pablo Castañeda-Casado, Edounou Jacques Gnambani, Domonbabele François de Sales Hien, Maurice Konkobo, Beatriz Urones, Isabelle Coppens, Alfonso Mendoza-Losana, Lluís Ballell, Abdoulaye Diabate, Thomas S Churcher, Marcelo Jacobs-Lorena

Science. 2023 Aug 4;381(6657):533-540. doi: 10.1126/science.adf8141. Epub 2023 Aug 3. 

https://pubmed.ncbi.nlm.nih.gov/37535741/

Cryptosporidium uses multiple distinct secretory organelles to interact with and modify its host cell

Amandine Guérin, Katherine M. Strelau, Konstantin Barylyuk, Bethan A. Wallbank, Laurence Berry, Oliver M. Crook, Kathryn S. Lilley, Ross F. Waller,, Boris Striepen

Cell Host Microbe. 2023 Apr 12;31(4):650-664.e6. doi: 10.1016/j.chom.2023.03.001. 

https://pubmed.ncbi.nlm.nih.gov/36958336/

Antiplasmodial peptaibols act through membrane directed mechanisms

Jennifer E. Collins, Jin Woo Lee, Frances Rocamora, Gagandeep S. Saggu, Karen L. Wendt, Charisse Flerida A. Pasaje, Sebastian Smick, Natalia Mojica Santos, Raphaella Paes, Tiantian Jiang, Nimisha Mittal, Madeline R. Luth, Taylor Chin, Howard Chang, James L. McLellan, Beatriz Morales-Hernandez, Kirsten K. Hanson, Jacquin C. Niles, Sanjay A. Desai, Elizabeth A. Winzeler, Robert H. Cichewicz, Debopam Chakrabarti

Cell Chem Biol. 2023 Nov 13:S2451-9456(23)00385-9.  doi: 10.1016/j.chembiol.2023.10.025.

https://pubmed.ncbi.nlm.nih.gov/37995692/

Quorum sensing-activated phenylalanine metabolism drives OMV biogenesis to enhance mosquito commensal colonization resistance to Plasmodium

Yongmao Jiang, Han Gao, Lihua Wang, Wenqian Hu, Guandong Wang, Sibao Wang

Cell Host Microbe. 2023 Oct 11;31(10):1655-1667.e6. doi: 10.1016/j.chom.2023.08.017. 

https://pubmed.ncbi.nlm.nih.gov/37738984/

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

Sachel Mok, Tomas Yeo, Davin Hong, Melanie J Shears, Leila S Ross, Kurt E Ward, Satish K Dhingra, Mariko Kanai, Jessica L Bridgford, Abhai K Tripathi, Godfree Mlambo, Anna Y Burkhard, Megan R Ansbro, Kate J Fairhurst, Eva Gil-Iturbe, Heekuk Park, Felix D Rozenberg, Jonathan Kim, Filippo Mancia, Rick M Fairhurst, Matthias Quick, Anne-Catrin Uhlemann, Photini Sinnis, David A Fidock

Sci Adv. 2023 Nov 10;9(45):eadi2364. doi: 10.1126/sciadv.adi2364. Epub 2023 Nov 8. 

https://pubmed.ncbi.nlm.nih.gov/37939186/

Gene-by-gene screen of the unknown proteins encoded on Plasmodium falciparum chromosome 3

Jessica Kimmel, Marius Schmitt, Alexej Sinner, Pascal Wilhelmus Theodorus Christianus Jansen, Sheila Mainye, Gala Ramón-Zamorano, Christa Geeke Toenhake, Jan Stephan Wichers-Misterek, Jakob Cronshagen, Ricarda Sabitzki, Paolo Mesén-Ramírez, Hannah Michaela Behrens, Richárd Bártfai, Tobias Spielmann

Cell Syst. 2023 Jan 18;14(1):9-23.e7. doi: 10.1016/j.cels.2022.12.001. 

https://pubmed.ncbi.nlm.nih.gov/36657393/

Revisiting the Plasmodium sporozoite inoculum and elucidating the efficiency with which malaria parasites progress through the mosquito

Sachie Kanatani, Deborah Stiffler, Teun Bousema, Gayane Yenokyan, Photini Sinnis

Nat Commun. 2024 Jan 25;15(1):748.  doi: 10.1038/s41467-024-44962-4.  

https://pubmed.ncbi.nlm.nih.gov/38272943/

Requirement of microtubules for secretion of a micronemal protein CpTSP4 in the invasive stage of the apicomplexan Cryptosporidium parvum

Dongqiang Wang, Peng Jiang , Xiaodong Wu, Ying Zhang, Chenchen Wang, Meng Li, Mingxiao Liu, Jigang Yin, Guan Zhu

mBio. 2024 Jan 24:e0315823. doi: 10.1128/mbio.03158-23. Online ahead of print. 

https://pubmed.ncbi.nlm.nih.gov/38265238/

A population modification gene drive targeting both Saglin and Lipophorin impairs Plasmodium transmission in Anopheles mosquitoes

Emily I GreenEtienne JaouenDennis KlugRoenick Proveti OlmoAmandine GautierStéphanie BlandinEric Marois

Elife. 2023 Dec 5:12:e93142. doi: 10.7554/eLife.93142. 

https://pubmed.ncbi.nlm.nih.gov/38051195/

Intracellular Plasmodium aquaporin 2 is important for sporozoite production in the mosquito vector and malaria transmission

Alexander J. Bailey, Chiamaka Valerie Ukegbu, Maria Giorgalli, Tanguy Rene Balthazar Besson, George K. Christophides,, Dina Vlachou

Proc Natl Acad Sci U S A. 2023 Oct 31;120(44):e2304339120. doi: 10.1073/pnas.2304339120. 

https://pubmed.ncbi.nlm.nih.gov/37883438/

Clinically relevant atovaquone-resistant human malaria parasites fail to transmit by mosquito

Victoria A. Balta, Deborah Stiffler, Abeer Sayeed, Abhai K. Tripathi, Rubayet Elahi, Godfree Mlambo, Rahul P. Bakshi, Amanda G. Dziedzic, Anne E. Jedlicka, Elizabeth Nenortas, Keyla Romero-Rodriguez, Matthew A. Canonizado, Alexis Mann, Andrew Owen, David J. Sullivan, Sean T. Prigge, Photini Sinnis, Theresa A. Shapiro

Nat Commun. 2023 Oct 12;14(1):6415. doi: 10.1038/s41467-023-42030-x. 

https://pubmed.ncbi.nlm.nih.gov/37828012/

Origin and arrangement of actin filaments for gliding motility in apicomplexan parasites revealed by cryo-electron tomography

Matthew Martinez, Shrawan Kumar Mageswaran, Amandine Guérin, William David Chen, Cameron Parker Thompson, Sabine Chavin, Dominique Soldati-Favre, Boris Striepen, Yi-Wei Chan

Nat Commun. 2023 Aug 9;14(1):4800. doi: 10.1038/s41467-023-40520-6. 

https://pubmed.ncbi.nlm.nih.gov/37558667/

mRNA vaccine against malaria tailored for liver-resident memory T cells

Mitch Ganley, Lauren E. Holz, Jordan J. Minnell, Maria N. de Menezes, Olivia K. Burn, Kean Chan Yew Poa, Sarah L. Draper, Kieran English, Susanna T. S. Chan, Regan J. Anderson, Benjamin J. Compton, Andrew J. Marshall, Anton Cozijnsen, Yu Cheng Chua, Zhengyu Ge, Kathryn J. Farrand, John C. Mamum, Calvin Xu, Ian A. Cockburn, Katsuyuki Yui, Patrick Bertolino, Stephanie Gras, Jérôme Le Nours, Jamie Rossjohn, Daniel Fernandez-Ruiz, Geoffrey I. McFadden, David F. Ackerley, Gavin F. Painter, Ian F. Hermans, William R. Heath

Nat Immunol. 2023 Sep;24(9):1487-1498. doi: 10.1038/s41590-023-01562-6. 

https://pubmed.ncbi.nlm.nih.gov/37474653/

Dual effector population modification gene-drive strains of the African malaria mosquitoes, Anopheles gambiae and Anopheles coluzzii

Rebeca Carballar-Lejarazú, Yuemei Dong, Thai Binh Pham, Taylor Tushar, Rodrigo M. Corder, Agastya Mondal, Héctor M. Sánchez C, Hsu-Feng Lee, John M. Marshall, George Dimopoulos, Anthony A. James

Proc Natl Acad Sci U S A. 2023 Jul 18;120(29):e2221118120. doi: 10.1073/pnas.2221118120. 

https://pubmed.ncbi.nlm.nih.gov/37428915/

Selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles

Kelsey L. Adams, Emily K. Selland, Bailey C. Willett, John W. Carew, Charles Vidoudez, Naresh Singh, Flaminia Catteruccia

PLoS Pathog. 2023 Jun 20;19(6):e1011448. doi: 10.1371/journal.ppat.1011448. 

https://pubmed.ncbi.nlm.nih.gov/37339122/

Conformational change of Plasmodium TRAP is essential for sporozoite migration and transmission

Friedrich Braumann, Dennis Klug, Jessica Kehrer, Gaojie Song, Juan Feng, Timothy A Springer, Friedrich Frischknecht

EMBO Rep. 2023 Jul 5;24(7):e57064. doi: 10.15252/embr.202357064. 

https://pubmed.ncbi.nlm.nih.gov/37306042/

Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies

Opeyemi Ernest Oludada, Giulia Costa, Clare Burn Aschner, Anna S Obraztsova, Katherine Prieto, Caterina Canetta, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmüller, Rajagopal Murugan, Jean‐Philippe Julien, Elena A Levashina, Hedda Wardemann

EMBO Mol Med. 2023 Jun 7;15(6):e17454. doi: 10.15252/emmm.202317454. 

https://pubmed.ncbi.nlm.nih.gov/37082831/

The claudin-like apicomplexan microneme protein is required for gliding motility and infectivity of Plasmodium sporozoites

Manon Loubens, Carine Marinach, Clara-Eva Paquereau, Soumia Hamada, Bénédicte Hoareau-Coudert, David Akbar, Jean-François Franetich, Olivier Silvie

PLoS Pathog. 2023 Mar 16;19(3):e1011261. doi: 10.1371/journal.ppat.1011261. 

https://pubmed.ncbi.nlm.nih.gov/36928686/

The salivary protein Saglin facilitates efficient midgut colonization of Anopheles mosquitoes by malaria parasites

Dennis Klug , Amandine Gautier, Eric Calvo, Eric Marois, Stéphanie A. Blandin

PLoS Pathog. 2023 Mar 2;19(3):e1010538. doi: 10.1371/journal.ppat.1010538. 

https://pubmed.ncbi.nlm.nih.gov/36862755/

A Microtubule-Associated Protein Is Essential for Malaria Parasite Transmission

Jan Stephan Wichers-Misterek, Annika M. Binder, Paolo Mesén-Ramírez, Lilian Patrick Dorner, Soraya Safavi, Gwendolin Fuchs, Tobias L. Lenz, Anna Bachmann, Danny Wilson, Friedrich Frischknecht, Tim-Wolf Gilberger

mBio. 2023 Feb 28;14(1):e0331822. doi: 10.1128/mbio.03318-22. 

https://pubmed.ncbi.nlm.nih.gov/36625655/

Knock-sideways by inducible ER retrieval enables a unique approach for studying Plasmodium- secreted proteins

Manuel A Fierro, Tahir Hussain, Liam J Campin, Josh R Beck 

Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2308676120. doi: 10.1073/pnas.2308676120.

https://pubmed.ncbi.nlm.nih.gov/37552754/

Plasmodium ARK2 and EB1 drive unconventional spindle dynamics, during chromosome segregation in sexual transmission stages

Mohammad Zeeshan, Edward Rea, Steven Abel, Kruno Vukušić, Robert Markus, Declan Brady, Antonius Eze, Ravish Rashpa, Aurelia C. Balestra, Andrew R. Bottrill, Mathieu Brochet, David S. Guttery, Iva M. Tolić, Anthony A. Holder, Karine G. Le Roch, Eelco C. Tromer, Rita Tewari

Nat Commun. 2023 Sep 13;14(1):5652. doi: 10.1038/s41467-023-41395-3.

https://pubmed.ncbi.nlm.nih.gov/37704606/

The following two papers should be introduced at the same time:

A spatiotemporally resolved single-cell atlas of the Plasmodium liver stage

Amichay Afriat, Vanessa Zuzarte-Luís, Keren Bahar Halpern, Lisa Buchauer, Sofia Marques, Ângelo Ferreira Chora, Aparajita Lahree, Ido Amit, Maria M. Mota, Shalev Itzkovitz

Nature. 2022 Nov;611(7936):563-569. doi: 10.1038/s41586-022-05406-5. 

https://pubmed.ncbi.nlm.nih.gov/36352220/

A single-cell liver atlas of Plasmodium vivax infection

Liliana Mancio-Silva , Nil Gural, Eliana Real, Marc H Wadsworth 2nd, Vincent L Butty, Sandra March, Niketa Nerurkar, Travis K Hughes, Wanlapa Roobsoong, Heather E Fleming, Charlie A Whittaker, Stuart S Levine, Jetsumon Sattabongkot, Alex K Shalek, Sangeeta N Bhatia

Cell Host Microbe. 2022 Jul 13;30(7):1048-1060.e5. doi: 10.1016/j.chom.2022.03.034. 

https://pubmed.ncbi.nlm.nih.gov/35443155/

Plasmodium invasion related

https://pubmed.ncbi.nlm.nih.gov/37713419/

https://pubmed.ncbi.nlm.nih.gov/37712738/

https://pubmed.ncbi.nlm.nih.gov/37708854/

https://pubmed.ncbi.nlm.nih.gov/37607941/

https://pubmed.ncbi.nlm.nih.gov/37489900/

https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011449

https://www.nature.com/articles/s41467-021-25309-9

https://www.nature.com/articles/s41590-023-01562-6