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Overview
Overview
Materials harvested from sources other than you such as amniotic fluid and or exosomes have been used to treat certain conditions. However, more research is continually being conducted to study the benefits of these treatments.
Amniotic fluid, which comes from the amniotic sac that surrounds a fetus during pregnancy, also contains hyaluronic acids that can help cartilage grow and lubricate joints. Amniotic fluid injections can help reduce inflammation and promote new tissue growth by signaling endogenous cells.
Exosomes are extracellular vesicles, or tiny bubbles, released by stem cells and other cell types to communicate with each other. They carry proteins, lipids, and nucleic acids, such as mRNA and microRNA, between cells, and the cargo within them can influence the behavior and function of recipient cells. Exosomes are thought to play a role in cell biology and are being explored as a potential way to deliver therapeutic molecules to specific cells in the body.
DISCLOSURE: As of February 2023, the FDA has not approved any exosome products. The FDA recommends that patients considering exosome therapy confirm that the product is FDA approved to reduce the risk of receiving an unapproved substance. Clinics that offer unapproved exosome products may make unsubstantiated claims about their potential to treat or cure diseases, and may put patients at risk by delaying or harming them. In addition, amniotic fluid injections are not FDA approved for pain management. The use of amniotic derivatives and exosomes is considered off label.
Research Studies
Research Studies
AMNIOTIC FLUID PRODUCTS
Are Amniotic Fluid Products Stem Cell Therapies? A Study of Amniotic Fluid Preparations for Mesenchymal Stem Cells With Bone Marrow Comparison. The AFPs studied should not be considered "stem cell" therapies, and researchers should use caution when evaluating commercial claims that products contain stem cells. Given their growth factor content, however, AFPs may still represent a promising tool for orthopaedic treatment.
FINAL DATABASE AK Medical Literature - Sports Medicine _ Orthobiologics & Injections.xlsxPage updated
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