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What body parts and conditions can be treated with PRP?
Hip ● Osteoarthritis [26] [28] ● Acute Hamstring Injuries [34] ● Proximal Hamstring Tendinopathy [33] ● Labral tear [20] ● Trochanteric bursitis [26] [27] [30]
Knee ● Osteoarthritis [10] [14] ● Patellar tendinosis [32]
Foot & Ankle ● Osteoarthritis [10] ● Achilles tendonitis and tendinosis [19] ● Plantar fasciitis [31] ● Ligament sprains and tears [24] 3
Shoulder ● Osteoarthritis [15] ● Ligament sprains and tears [16] ● Tendonitis and tendinosis [18] ● Acromioclavicular joint dysfunction and pain [16]
Elbow, Hand & Wrist ● Osteoarthritis [25] ● Epicondylitis (tennis and golfer’s elbow) [21] [22] ● Tendonitis and tendinosis [18]
Spine / Back ● Degenerative Disc Disease [17] ● Facet joint osteoarthritis [23] Sacroiliac Joint Dysfunction [29]
[1] Mishra, A., & Pavelko, T. (2006). Treatment of Chronic Elbow Tendinosis with Buffered Platelet-Rich Plasma. The American Journal of Sports Medicine, 34(11), 1774–1778. https://doi.org/10.1177/0363546506288850
[2] Mandle, R. (2016). Research Study: Comparison of EmCyte GS30-PurePRP II, EmCyte GS60-PurePRP II, Arteriocyte MAGELLAN, Stryker REGENKIT THT, and ECLIPSE PRP [White Paper]. Biosciences Research Associates. https://drive.google.com/file/d/15CsBI91_23glkmMfecv0HwsgTUBWYA13/view
[3] Mautner, K., Malanga, G. A., Smith, J., Shiple, B., Ibrahim, V., Sampson, S., & Bowen, J. E. (2015). A call for a standard classification system for future biologic research: the rationale for new PRP nomenclature. PM & R : the journal of injury, function, and rehabilitation, 7(4 Suppl), S53–S59. https://doi.org/10.1016/j.pmrj.2015.02.005
[4] Dohan Ehrenfest, D. M., Pinto, N. R., Pereda, A., Jiménez, P., Corso, M. D., Kang, B. S., Nally, M., Lanata, N., Wang, H. L., & Quirynen, M. (2018). The impact of the centrifuge characteristics and centrifugation protocols on the cells, growth factors, and fibrin architecture of a leukocyte- and platelet-rich fibrin (L-PRF) clot and membrane. Platelets, 29(2), 171–184. https://doi.org/10.1080/09537104.2017.1293812
[5] Louis, M. L., Magalon, J., Jouve, E., Bornet, C. E., Mattei, J. C., Chagnaud, C., Rochwerger, A., Veran, J., & Sabatier, F. (2018). Growth Factors Levels Determine Efficacy of Platelets Rich Plasma Injection in Knee Osteoarthritis: A Randomized Double Blind Noninferiority Trial Compared With Viscosupplementation. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 34(5), 1530–1540.e2. https://doi.org/10.1016/j.arthro.2017.11.035 7
[6] Halpern, B., Chaudhury, S., Rodeo, S. A., Hayter, C., Bogner, E., Potter, H. G., & Nguyen, J. (2013). Clinical and MRI outcomes after platelet-rich plasma treatment for knee osteoarthritis. Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 23(3), 238–239. https://doi.org/10.1097/JSM.0b013e31827c3846
[7] Wu, P. I., Diaz, R., & Borg-Stein, J. (2016). Platelet-Rich Plasma. Physical medicine and rehabilitation clinics of North America, 27(4), 825–853. https://doi.org/10.1016/j.pmr.2016.06.002
[8] Riboh, J. C., Saltzman, B. M., Yanke, A. B., Fortier, L., & Cole, B. J. (2016). Effect of Leukocyte Concentration on the Efficacy of Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis. The American journal of sports medicine, 44(3), 792–800. https://doi.org/10.1177/0363546515580787
[9] Chang, K. V., Hung, C. Y., Aliwarga, F., Wang, T. G., Han, D. S., & Chen, W. S. (2014). Comparative effectiveness of platelet-rich plasma injections for treating knee joint cartilage degenerative pathology: a systematic review and meta-analysis. Archives of physical medicine and rehabilitation, 95(3), 562–575. https://doi.org/10.1016/j.apmr.2013.11.006
[10] Görmeli, G., Görmeli, C. A., Ataoglu, B., Çolak, C., Aslantürk, O., & Ertem, K. (2015). Multiple PRP injections are more effective than single injections and hyaluronic acid in knees with early osteoarthritis: A randomized, double-blind, placebo-controlled trial. Knee Surgery, Sports Traumatology, Arthroscopy, 25(3), 958-965. doi:10.1007/s00167-015-3705-6
[11] Guney, A., Yurdakul, E., Karaman, I., Bilal, O., Kafadar, I. H., & Oner, M. (2015). Medium-term outcomes of mosaicplasty versus arthroscopic microfracture with or without platelet-rich plasma in the treatment of osteochondral lesions of the talus. Knee Surgery, Sports Traumatology, Arthroscopy, 24(4), 1293-1298. doi:10.1007/s00167-015-3834-y
[12] Belk, J. W., Kraeutler, M. J., Houck, D. A., Goodrich, J. A., Dragoo, J. L., & Mccarty, E. C. (2020). Platelet-Rich Plasma Versus Hyaluronic Acid for Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Controlled Trials. The American Journal of Sports Medicine, 036354652090939. doi:10.1177/0363546520909397
[13] Kaminski, R., Maksymowicz-Wleklik, M., Kulinski, K., Kozar-Kaminska, K., Dabrowska-Thing, A., & Pomianowski, S. (2019). Short-Term Outcomes of Percutaneous Trephination with a Platelet Rich Plasma Intrameniscal Injection for the Repair of Degenerative Meniscal Lesions. A Prospective, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study. International Journal of Molecular Sciences, 20(4), 856. doi:10.3390/ijms20040856
[14] Huang, G., Hua, Yang, Ma, Yu, & Chen. (2018). Platelet‐rich plasma shows beneficial effects for patients with knee osteoarthritis by suppressing inflammatory factors. Experimental and Therapeutic Medicine, 15, 3096–3102.
[15] Cai, Y., Sun, Z., Liao, B., Song, Z., Xiao, T., & Zhu, P. (2019). Sodium Hyaluronate and Platelet-RichPlasma for Partial-Thickness Rotator Cuff Tears. Medicine & Science in Sports & 8 Exercise, 51(2), 227-233. doi:10.1249/mss.0000000000001781 [16] PASİN, T., ATAOĞLU, S., PASİN, Ö., & Ankarali, H. (2019). Comparison of the Effectiveness of Platelet-Rich Plasma, Corticosteroid, and Physical Therapy in Subacromial Impingement Syndrome. Arch Rheumatol, 34(3), 308–316.
[17] Tuakli-Wosornu, Y., MD, MPH, Terry, A., MD, Boachie-Adjei, K., BS, CPH, Harrison, J., BS, Gribbin, C., BA, LaSalle, E., BS, . . . Lutz, G., MD. (2016). Lumbar Intradiskal Platelet-Rich (PRP) Injections: A Prospective, Double-Blind, Randomized Controlled Study. PM&R, 8.
[18] Chen, X., Jones, I., Park, C., & Vangsness, C. (2018). The Efficacy of Platelet-Rich Plasma on Tendon and Ligament Healing: A Systematic Review and Meta-Analysis with Bias Assessment. Am J Sports Med, 46(8).
[19] Alsousou, J., Handley, R., Thompson, M., McNally, E., Harrison, P., & Willett, K. (2018). PLATELET RICH PLASMA IN ACCELERATED ACHILLES TENDON REGENERATION: A RANDOMIZED CONTROLLED TRIAL. Orthopaedic Proceedings, 94.
[20] DeLuigi, A. J., Blatz, D., Karam, C., Gustin, Z., & Gordon, A. H. (2019). Use of Platelet-Rich Plasma for the Treatment of Acetabular Labral Tear of the Hip: A Pilot Study. Am J Phys Med Rehabil, 98(11), 1010–1017.
[21] Behera, P., Dhillon, M., Aggarwal, S., Marwaha, N., & Prakash, M. (2015). Leukocyte-poor platelet-rich plasma versus bupivacaine for recalcitrant lateral epicondylar tendinopathy. J Orthop Surg (Hong Kong), 1, 6–10.
[22] Yadav, R., Kothari, S. Y., & Borah, D. (2015). Comparison of Local Injection of Platelet Rich Plasma and Corticosteroids in the Treatment of Lateral Epicondylitis of Humerus. Journal of Clinical and Diagnostic Research, 9(7), RC05–RC07.
[23] Wu, J., Zhou, J., Liu, C., Zhang, J., Xiong, W., Lv, Y., … Liu, Q. (2017). A Prospective Study Comparing Platelet-Rich Plasma and Local Anesthetic (LA)/Corticosteroid in Intra-articular Injection for the Treatment of Lumbar Facet Joint Syndrome. Pain Practice, 17(7), 914–924.
[24] Boesen, A. P., Hansen, R., Boesen, M. I., Malliaras, P., & Langberg, H. (2017). Effect of High-Volume Injection, Platelet-Rich Plasma, and Sham Treatment in Chronic Midportion Achilles Tendinopathy. The American Journal of Sports Medicine, 45(9).
[25] Malahias, M. A., Roumeliotis, L., Nikolaou, V. S., Chronopoulos, E., Sourlas, I., & Babis, G. C. (2018). Platelet-Rich Plasma versus Corticosteroid Intra-articular Injections for the Treatment of Trapeziometacarpal Arthritis: A Prospective Randomized Controlled Clinical Trial. Cartilage.
[26] Ali, M., Mohamed, A., Ahmed, H. E., Malviya, A., & Atchia, I. (2018). The use of ultrasound-guided platelet-rich plasma injections in the treatment of hip osteoarthritis: a systematic review of the literature. J Ultrason, 18, 332–337. [27] Begkas, D., Chatzopoulos, S.-T., Touzopoulos, P., Balanika, A., & Pastroudis, A. (2020). 9 Ultrasound-Guided Platelet-rich Plasma Application Versus Corticosteroid Injections for the Treatment of Greater Trochanteric Pain Syndrome: A Prospective Controlled Randomized Comparative Clinical Study. Cureus.
[28] Dallari, D., MD, Stagni, C., MD, Rani, N., MD, Sabbioni, G., MD, Pelotti, P., MD, Torricelli, P., BSc, . . .Giavaresi, G., MD. (2016). Ultrasound-Guided Injection of Platelet-Rich Plasma and Hyaluronic Acid, Separately and in Combination, for Hip Osteoarthritis. The American Journal of Sports Medicine, 44(3).
[29] Singla, V., Batra, Y., Bharti, N., Goni, V., & Marwaha, N. (2016). Steroid vs. Platelet-Rich Plasma in Ultrasound-Guided Sacroiliac Joint Injection for Chronic Low Back Pain. Pain Practice, 17(6), 782-791.
[30] Fitzpatrick, J., PhD, MBBS, FACSEP, Bulsara, M., PhD, O' Donnell, J., FRACS, MBBS, & Zheng, M., PhD, DM, FRCPath, FRCPA. (2019). Leucocyte-Rich Platelet-Rich Plasma Treatment of Gluteus Medius and Minimus Tendinopathy. The American Journal of Sports Medicine, 47(5), 1130-1137.
[31] Vahdatpour, B., Kianimehr, L., Moradi, A., & Haghighat, S. (2016). Beneficial Effects of Platelet-Rich Plasma on improvement of Pain Severity and physical disability in patients with plantar fasciitis: A randomized trial. Advanced Biomedical Research, 5. doi:10.4103/2277-9175.192731:
[32] Dupley, L., & Charalambous, C. P. (2017). Platelet-Rich Plasma Injections as a Treatment for Refractory Patellar Tendinosis: A Meta-Analysis of Randomised Trials. Knee Surgery & Related Research, 29(3), 165-171. doi:10.5792/ksrr.16.055
[33] Davenport, K. L., Campos, J. S., Nguyen, J., Saboeiro, G., Adler, R. S., & Moley, P. J. (2015). Ultrasound-Guided Intratendinous Injections With Platelet-Rich Plasma or Autologous Whole Blood for Treatment of Proximal Hamstring Tendinopathy. Journal of Ultrasound in Medicine, 34(8), 1455-1463. doi:10.7863/ultra.34.8.1455
[34] Bradley, J., MD, Lawyer, T., MD, Ruef, S., MA, Towers, J., MD, & Arner, J., MD. (2020). Platelet-Rich Plasma Shortens Return to Play in National Football League Players with Acute Hamstring Injuries. The Orthopaedic Journal of Sports Medicine, 8(4). doi:10.1177/2325967120911731
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