LECTURE
唯天下至誠 爲能化
唯天下至誠 爲能化
Basic principles of drug action
Text: Basic & Clinical Pharmacology16th ed
Undergraduate (4th, 1st semester, 3 credit)
Introduction (1/1) | What is Pharmacology?/What is Drug? (2/2) Chapter 1
Pharmacodynamics – General Principles(3/3)/Molecular Basis (3/3) Chapter 2/3
Pharmacokinetics | Biotransformation (3/3) Chapter 4
Introduction to Autonomic Pharmacology (3/3) Chapter 6
Cholinoceptor Agonists and Antagonists (3/6) Chapter 7
Cholinoceptor Agonists and Antagonists (3/6) Chapter 8
Adrenoceptor Agonists and Antagonists (3/3) Chapter 9/10
Mid-term Exam
Vasoactive Mediators (3/3) Chapter 17/19
Diuretic Agents (3/3) Chapter 15
Antihypertensive Agents (3/3) Chapter 11
Vasodilators & the Treatment of Angina (3/3) Chapter 12
Cardiac Pharmacology (Drugs used in Heart Failure) (3/3) Chapter 13
Cardiac Pharmacology (Drugs used in Arrhythmia) (3/3) Chapter 14
Final Exam
Drugs affecting major systems
Text: Basic & Clinical Pharmacology16th ed
Undergraduate (4th, 2nd semester, 2 credit)
Introduction (0.5/0.5)│Histamine and antihistamines (1.5/1.5) Chapter 16
Serotonin & the Erogot Alkaloids (2/2) Chapter 16
The Eicosanoids: PGs, TXs, LTs, & Related Compounds (2/2) Chapter 18
Drugs Used in Asthma (2/2) Chapter 20
Gastrointestinal Pharmacology (2/2) Chapter 62
Cancer: Chemotherapy I (2/4) Chapter 54
Cancer: Target therapy II (2/4) Chapter 54
Mid-term Exam
Immunopharmacology (2/2) Chapter 55
Introduction to antimicrobial agents (2/2) Chapter 43
Cell wall synthesis inhibitors (2/2) Chapter 44
Protein synthesis inhibitors (2/2) Chapter 45
Sulfonamides, & Quinolones (1/1)│Antimycobacterial Drugs (1/1) Chapter 46/47
Antifungals (1/1) │Antivirals (1/1) Chapter 48/49
Final Exam
Advances in drug actions
New FDA Approved Drugs
Undergraduate (5th, 2nd semester, 2 credit)
Introduction/Targets for Drug Action
How drugs act: Cellular aspect
New drugs for CVD(1)
New drugs for CVD(2)-dyslipidemia & anti-coagulants
Eicosanoids-lipoxins
Drugs for dopaminergic transmission
Drugs for GABAergic and glutamatergic transmission
Mid exam
Pain transmission: opioids & drug abuse
New drugs for endocrinology
Biologics, biosimiliar & biobetter
New drugs for oncology
Orphan drugs- cystic fibrosis
Orphan drugs- DMD
Final exam
Novel targets for first-in class drugs
New drugs under development
Graduate program
Introduction
What could serve as a druggable target?
How do I choose a drug target for my research?
Example of target validation
Ongoing project for new drug development
Research article
Research article
Research article
Research article
Research article
Research article
Research article
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Research article
Closing