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不亦樂乎
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Graduate students: PhD, MS course
Researchers: Research professor, PostDoc
Research associates: Internship (undergraduate student)
Apply: e-mail and interview
[2025.10.21] Congratulations!🎉 Yena’s 10th paper has been accepted in Experimental & Molecular Medicine (IF 12.9, 4.2%)
This article addresses a fundamental biological question: how do cells maintain a consistent amount of protein within themselves? It presents a comprehensive review of the mechanisms that regulate the total levels of actin and tubulin—the most abundant cellular proteins—drawing on findings from our laboratory and recent research advances. Through this work, the study deepens our understanding of essential life processes.
🎉 Congratulations to Yena on your 10th publication (13th including co-authored works)!
[2025.010.18] Congratulations! 🎉 Yena Cho Honored with a “Triple Crown”
Yena Cho has been honored with a remarkable “triple crown,” receiving the Moon Sook Saebyul Award (문숙 새별여성과학자상) from WBF, the Outstanding Young Researcher Award (미래약학우수논문상) from the Pharmaceutical Society of Korea, and the Next-Generation Pharmacologist Award (차세대 약리학자상) from the Korean Society of Pharmacology.
Congratulations to Yena for this outstanding achievement.
[2025.10.03] Congratulations!🎉 Yena’s 9th paper has been accepted in Molecular Medicine (IF 6.4, 15.0%)
This article is concise and impactful, aiming for quick communication rather than an in-depth exploration.
Cho, Y., Kim, YK. Context-Specific Applications of CARM1 Inhibitors: Functional Profiles of EZM2302 and TP-064. Mol Med, (accepted October 03, 2025)
Congratulations on your 9th (12th) publication !
[2025.09.12] Congratulations!🎉 Yena Honored with the Moon Sook Saebyul Award
Yena Cho received the Moon Sook Saebyul Award at the Women’s Bioscience Forum (WBF) on September 12, along with a prize of 1,000,000 KRW. 🗞️SM NEWS, WBF
This prestigious award recognizes outstanding young female life scientists who are currently pursuing their Ph.D. or conducting postdoctoral research.
Congratulations once again to Yena on this remarkable achievement!
[2025.09.01] New members
Dr SK Choi has joined our lab as a postdoctoral researcher. Welcome!
YG Woo has been admitted to the master's program in the graduate school.
[2025.08.27] Congratulations!🎉 Yena’s 8th paper has been accepted in Cell Communication and Signaling (IF 8.9, 15.2%)
After a long and challenging journey, the CARM1–Tubulin story has come to a close. Heartfelt thanks to Yena for her patience and dedication.
Cho, Y., Hwang, J.W., Bedford, M.T. et al. Reversible arginine methylation of PI3KC2α controls mitotic spindle dynamics. Cell Commun Signal 23, 409 (2025). https://doi.org/10.1186/s12964-025-02419-1 (published October 02, 2025)
Congratulations on your 8th (11th) publication — an inspiring milestone!
[2025.08.07] Congratulations!🎉 Yena’s 7th paper has been accepted in Experimental & Molecular Medicine (IF 12.9, 4.2%)
This article highlights the multifaceted functions of CARM1, extending beyond its well-established role in histone methylation to encompass the modification of diverse non-histone substrates and emerging non-enzymatic scaffolding activities. Many of the novel functions discussed were first identified and characterized by Yena in our lab.
Congratulations to Yena on her 7th (10th including co-authored works) publication)—a remarkable milestone that reflects her dedication, perseverance, and scientific excellence!
[2025.02.26] Being awarded Research Grant from NRF
Our lab has been awarded a Research Grant from the National Research Foundation of Korea (NRF) for the project titled "Dynamic Regulation of Mitochondrial Arginine Methylation: Its Involvement in Doxorubicin-Induced Cardiotoxicity" (Grant No. RS-2025-00563180). We will receive 1,000,000,000 KRW over the next five years to support our research.
[2025.02.23] Congratulations!🎉 Yena's sixth paper has been accepted in Cell Communication and Signaling (IF 8.2, 15.97%)
Cho Y, Hwang JW, Bedford MT, Song DG, Kim SN, Kim YK. CARM1 regulates tubulin autoregulation through PI3KC2α R175 methylation. Cell Communication and Signaling, 2025; 23, 120 (published March 06, 2025)
This study has finally been accepted after a long and challenging journey.We sincerely thank Yena for her patience and hard work, and celebrate this achievement together.
[2025.02.14] Congratulations to Yena on the acceptance of her fifth paper in Cell Death & Disease! (IF 8.1, 16.49%)
Cho Y, DG Song, SN Kim, Kim YK. CARM1 S217 phosphorylation by CDK1 in late G2 phase facilitates mitotic entry. Cell Death & Disease, 2025; 16, 202 (published March 25, 2025)
It was not easy to defend the paper against rigorous reviewers, but she has finally achieved a great outcome. We deeply admire her perseverance and sincerely celebrate its final acceptance!
[2025.02.11] 2024 MPRC Winter Workshop
[2025.02.11] 2024 MPRC Winter Workshop
YK Kim
Multifaceted Roles of CARM1 Beyond Nuclear Function
Y Cho, awarded the Excellent Student Research from MPRC
SH Park, YG Woo, NY Kim, a ceremony for 2024 MPRC winter internship
[2025.01.24] 22nd MART meeting
[2025.01.24] 22nd MART meeting
Monthly Joint Meeting with YK-WY-TH Lab
Yena Cho
The role of H3R17me2a mark in mitosis
Attendee: SH Park, YG Woo, NY Kim
SG Choi, SJ Ha, SY Choi, JY Lee, SW Lee
SA Lee, YY Lee
2024.11.12(Tue) - ZOOM
Yena Cho
Regulation of mitochondrial dynamics through CARM1-DRP1 axis
[2024.11.01] 19th MART meeting
[2024.11.01] 19th MART meeting
Monthly Joint Meeting with YK-WY-TH Lab
Yunae Jeong
- Yunae's first presentation debutDrug Repositioning: Proguanil as a Potential PRMT Inhibitor for Cancer Therapy
[2024.10.21]
[P1-26] CARM1 phosphorylation at S595 by p38γ MAPK drives ROS-mediated cellular senescence
[2024.09.04] Congratulations on the acceptance of "Yena's CARM1-DRP1 story 2" in Redox Biology (IF 10.7)
[2024.08.26] 17th MART meeting
[2024.08.26] 17th MART meeting
Monthly Joint Meeting with YK-WY-TH Lab
Songah Lee, APAP toxicity and latate
Yong Kee Kim, CARM1-mediated methylation of PI3KC2α regulates tubulin autoregulation and microtubule dynamics
[2024.08.21] 2024 MPRC Summer Workshop
2024.08.19(Mon)~21(Wed)
ELYSIAN Gangchon
Yena, awarded the Excellent Student Research from MPRC
Yunae, a completion ceremony for 2024 MPRC summer internship
[2024.07.22] 16th MART meeting
[2024.07.22] 16th MART meeting
Monthly Joint Meeting with YK-WY-TH Lab
Yena Cho, CARM1 S217 phosphorylation by CDK1 in late G2 phase facilitates mitotic entry
Seokgyeong Choi, Transcriptional Suppression of IRF9 Induces PARP Inhibitor Resistance
[2024.07.01] 2024 Pharmacology Summer Symposium
[2024.07.01] 2024 Pharmacology Summer Symposium
2024.07.01(Mon) ~ 07.02(Tue), Lotte Resort, Sokcho
Awarded for excellent presentation
ROS-mediated cytoplasmic localization of CARM1 induces mitochondrial fission through DRP1 methylation - Yena Cho
[2024.06.24] 2024 PhD Candidate Fellowship from NRF
Congratulations! Yena
Awarded the 2024 PhD Candidate Fellowship from NRF
Regulation of mitochondrial dynamics through CARM1-DRP1 axis (2024.09-2026.08)
🗞️SM NEWS
[2024.05.24] Congratulations on the acceptance of "Yena's CARM1-DRP1 story" in Redox Biology (IF 11.4)
[2024.01.29] 11th MART meeting
[2024.01.29] 11th MART meeting
Monthly Joint Meeting with YK-WY-TH Lab
2024.01.29(Mon) 16:00~ 18:00 (Pharm#606)
JH Im : AMC9005 ameliorates hepatocellular senescence by stimulating AMPK/PGC1a
Y Cho: CARM1 regulation of mitochondrial function
[2023.10.25] Congratulations, Yena, on being awarded Outstanding Poster Presentation Award at the 2023 Fall International Convention of PSK
[2023.10.02] 2023 8th MART meeting
[2023.10.02] 2023 8th MART meeting
2023.10.02(Mon) 10:00am~ 12:00pm (Pharm#606)
Monthly Joint Meeting with YK-WY-TH Lab
Park CW : Cori Cycle revisited: Potential therapeutic implications in NASH
Cho Y : Dynamic regulation of mitochondrial function by protein arginine methylation
[2023.08.29] 2023 7th MART meeting
[2023.08.29] 2023 7th MART meeting
2023.08.29(Tue) 4:00pm~ 6:00pm
Pharm#606 & Jang Jae-Geun Sushi
Monthly Joint Meeting with YK-WY-TH Lab
Presentation: JH Lim, WY Kim
[2023.08.22] 2023 MPRC Summer Research Workshop
[2023.08.22] 2023 MPRC Summer Research Workshop
2023.08.22(Tue)-23(Wed)
Pharmacy Building #601/Pocheon Oneul Resort
Title: Discovery of epigenetic drugs targeting mitochondrial homeostasis- Y CHo & YK KIm
[2023.08.09] Free Radical Biology & Medicine
- after accepting SPC-180002 story in FRBM
[2023.08.09] Free Radical Biology & Medicine
- after accepting SPC-180002 story in FRBM
2023.08.09 Saltim Bocca Y Cho, JY Yang , YK Kim
SPC-180002, a SIRT1/3 dual inhibitor, impairs mitochondrial function and redox homeostasis and represents an antitumor activity
Cho Y, Hwang JW, Park NJ, Moon J, Ali KH, Seo YH, Kim IS, Kim SN, Kim YK
Free Radic Biol Med. 2023 Nov 1; 208:73-88; https://doi.org/10.1016/j.freeradbiomed.2023.07.033
[2023.07.31] Congratulations on the acceptance of "Yena's #5 story" in FRBM (IF 7.4)
Cho Y, Hwang JW, Park NJ, Moon J, Ali KH, Seo YH, Kim IS, Kim SN, Kim YK. SPC-180002, a SIRT1/3 dual inhibitor, impairs mitochondrial function and redox homeostasis and represents an antitumor activity. Free Radical Biology & Medicine. 2023 Nov 1; 208:73-87; https://doi.org/10.1016/j.freeradbiomed.2023.07.033
🗞️숙약뉴스
[2023 07.28] 2023 DIRI Research Conference
- Mitochondria in the pathogenesis of metabolic disease
- 2023 07.28 (Fri) 15:00~17:30
[2023 07.28] 2023 DIRI Research Conference
- Mitochondria in the pathogenesis of metabolic disease
- 2023 07.28 (Fri) 15:00~17:30
15:00-15:35 Yong Kee Kim (SMWU), Regulation of Mitochondrial Dynamics by PRMTs
15:35-16:10 Yoon-Seok Noh (CBU), UBE2N alleviates defective mitophagy by promoting SQSTM1
16:10-16:45 Hyon-Seung Yi, (CNU Hospital), Role of mitoribosomal defects in fatty liver and cancer
16:45-17:20 Dongryeol Ryu (GIST), Finding biomarkers for sarcopenia and muscle Aging
[2023.10.25] Congratulations, Yena, on being awarded Outstanding Poster Presentation Award at the 2023 Spring International Convention of PSK (Lahan Select Gyeongju)
[P1-62] CARM1 methylates PI3KC2α to regulate microtubule dynamics 🗞️숙약뉴스
Seminar, Konkuk University College of Medicine
Seminar, Konkuk University College of Medicine
Yong Kee Kim, PhD, 2023.04.12
Protein Arginine Methylation: Regulation of Cellular Homeostasis
Completion - 2022 Winter Internship
Completion - 2022 Winter Internship
Feb 24, 2023
- MK Cho, SW Kwon, YW Na
- successfully completed their internships
- experimental languages for innovative research
- cell culture, cell viability assay, western blot, qPCR etc
Ahyeon Jeong, MSc
Feb 24, 2023: received MS degree
Dissertation: PRMT7 inhibitor SGC8158 enhances doxorubicin-induced DNA damage and its cytotoxicity.
Research: PRMT7 & DNA damage response
Oct. 21th (Fri) 08:30-09:10 Landing Ballroom A
: Research regions: P1. Pharmacology / P5. Microbiology / Immunology
: Ahyeon Jeong (College of Pharmacy, Sookmyung Women's University)
[PI-97] PRMT7 inhibitor SGC8158 potentiates doxorubicin-induced DNA damage and its cytotoxicity
Congratulation: awarded Oral Presentation Award
International journal of Molecular Sciences
- after accepting PRMT7 story in IJMS
International journal of Molecular Sciences
- after accepting PRMT7 story in IJMS
2022.10.13 605 A Jeong, Y Cho, SN Kim, YK Kim
PRMT7 inhibitor SGC8158 enhances doxorubicin-induced DNA damage and its cytotoxicity.
Jeong A, Cho Y, Cho M, Bae GU, Song DG, Kim SN, Kim YK
Int. J. Mol. Sci. 2022, 23(20), 12323; https://doi.org/10.3390/ijms232012323
Farewell! - 2022 SUMMER Internship
Farewell! - 2022 SUMMER Internship
Aug 22, 2022, at Pho Lime
JY Han (MK Cho, HJ Kwon, A Jeong, SJ Choi, Y Cho, YK Kim)
- successfully completed her internship (2022.06.27~ 08.24)
- Understanding and training of experimental languages for creative research
: cell culture, cell viability assay- MTT assay, western blot, RT-qPCR etc
CAFE604
CAFE604
2022.08.01.(Mon)
15 Me signature! 1.5 Autophagy 8.0
PRMT1 3.0 Mitochondria hot! 8.0
CARM1 best! 3.0 Microtubule 8.0
PRMT5 3.0 DDR 10
PRMT6 3.0 MDR sold out!
RDMs new! 4.5 Cell cycle hit! 10
Mol Cell 20 Life class 10
Nat Communs 20 Book club 10
Nat Chem Biol 20 Pharmacology 20
Nat Cell Biol 30
Nature 40 LEAP into your own world..
2022 DIRI Research Conference
- Mitochondria and metabolic disease
- 2022 07.14 (Thu) 15:00~17:00
2022 DIRI Research Conference
- Mitochondria and metabolic disease
- 2022 07.14 (Thu) 15:00~17:00
The novel role of Gα12 in mitochondrial function and metabolic disease
(Tae-Hyun Kim, Sookmyung Univ. College of Pharmacy)Dynamic regulation of mitochondrial metabolism in metabolic disease
(Hye-Jin Yoon, UNIST)Dynamin-related Protein 1 (Drp1) for the Coordination of Mitochondrial Structure and Function (Woong Sun, Korea Univ. College of Medicine)
2022 Summer Research Conference, PSK Pharmacolgy
- Molecular targets for new drug development
2022 Summer Research Conference, PSK Pharmacolgy
- Molecular targets for new drug development
Jun 27-28, 2022, SOKCHO Lotte Resort
- Attendee: YK Kim, A Jeong, HY Kwon, MK Cho, JY Han
Jun 01, 2022 - May 31, 2029
- GU Bae, YK Kim,CY Jang, GB Kang, TH Kim, SY Lee, MH Lee, KM Choi
- Understanding muscle physiome-based muscle dynamics
- Securing source technology for muscle-related disease
- Muscle dynamics, muscle diseases, neuromuscular junction, PRMTs
- 2022년 선도연구센터 현판 수여식(과학기술정보통신부): 2022 07.11(Mon)
Farewell! - 2021 Winter Internship
Farewell! - 2021 Winter Internship
Feb 25, 2022
- YH Kim, JH Lee, MK Cho
- successfully completed their internships
Congrat! Graduation
Congrat! Graduation
Feb 25, 2022
- Y Cho, Y Hong
- received PharmD degree
RIPS Seminar, Excellent Research in 2020
RIPS Seminar, Excellent Research in 2020
SOOKMYUNG College of Pharmacy
SOOKMYUNG College of Pharmacy
Yena Cho, 2021.02.15-22
A strategy for development of anticancer drug to overcome multidrug resistance
RIPS Seminar, SOOKMYUNG College of Pharmacy
RIPS Seminar, SOOKMYUNG College of Pharmacy
Jee Won Hwang, PhD, 2020.09.17
PRMT5 promotes DNA repair through methylation of 53BP1 and is regulated by Src-mediated phosphorylation
Lab Renovation
Lab Renovation
2020.08.27
Lab Remodeling for future innovative research
Set up an optimal research environment
Seminar, KIST Gangneung
Seminar, KIST Gangneung
YK Kim and JW Hwang, 2020.08.14
1) A novel microtubule inhibitor
2) PRMT5 and DNA repair
Seminar, Samik Pharm. Co., Ltd.
Seminar, Samik Pharm. Co., Ltd.
Yong Kee Kim, PhD, 2020.07.28
Protein Arginine Methyltransferases, A Novel Target for Cancer Therapy
Communications Biology
- after accepting PRMT5 story in Commun Biol
Communications Biology
- after accepting PRMT5 story in Commun Biol
2020.07.23 Some Sevit JW Hwang, Y Cho, YK Kim
Nature Communications
- after accepting PRMT6 story in Nat Commun
Nature Communications
- after accepting PRMT6 story in Nat Commun
2020.01.15. Yongsan Dragon City Hotel
HD Kim, KB Kang, GU Bae,
WY Kim, YK Kim, CY Jang
2020.01.20 JEULGEOBSO
- JW Han, WY Kim, GY Bae
Mina Park, MSc
Feb 25, 2020: received MS degree
Dissertation: Anti-proliferative effect of the substituted chromone on multidrug resistant cancer cells
2020.08.24 -photo
Welcome HOME
Welcome HOME
Feb 25, 2020
Back to the AdoMet Lab after completing KAPE activities
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