M.ª João Meneses, M.Sc

PTDC/BIM-MET/4712/2014: "Obesitility – Gut hormones and testicular metabolism: mechanisms associated with obesity-related male infertility"- PI: Dr. Marco G. Alves

PTDC/BIM-MET/4265/2014: "Prognostic and Protective Roles of the Clusterin-PON1 axis Against Obesity Complications" - PI: Prof. João Raposo (FCM|NMS-UNL)

"Intrinsic Disability of Sphincter - Study of differences in collagen type and collagenolysis process of urethral support tissue"- Co-Principal Investigators: Pedro Fontes Oliveira, Bercina Candoso and Mário Sousa. Portuguese Society Of Gynecology.

2020 - Grant from SPD&Lilly to participate on the 56th Annual Meeting of the European Association for the Study of Diabetes (Virtual)

2018 - Travel Grant from SPD&Lilly to participate on the 54th Annual Meeting of the European Association for the Study of Diabetes

2018 - Travel Grant to participate on the 52nd Annual Scientific Meeting of the European Society for Clinical Investigation

2018 - "GIFT Research Grant" from the Group of Fundamental and Translational Research of the Portuguese Society of Diabetology (SPD).

2017 - Best Poster in Basic Research, 13th Portuguese Congress of Diabetes, Epic Sana Algarve Hotel, Albufeira, Portugal, 10-12 March 2017

2016 - Best Poster in Basic Research, I Symposium in Diabesity and Fertility, UMIB-ICBAS, 22-23 September 2016

2015 - 4-year PhD fellowship from the Portuguese Foundation for Science and Technology (FCT).

2016 - Fellowship to participate in the 4th DZD Diabetes Research School. September 11-13, Munich, Germany

15. Meneses MJ, Pina AF, Sousa-Lima I, Patarrão RS, Ribeiro RT, Gardete-Correia L, Duarte R, Boavida JM, Correia I, Andrade R, Medina JL, Raposo JF, Macedo MP (2020) Paraoxonase-1 and Apolipoprotein J as biomarkers in dysmetabolism: a cluster analysis. Diabetologia. 63 (Suppl 1): S425.

14. Sousa-Lima I, Patarrão RS, Meneses MJ, Pina AF, Coelho M, Raposo JF, Ribeiro RT, Gardete-Correia L, Duarte R, Boavida JM, Correia I, Andrade R, Medina JL, Jones, JG, Macedo MP (2020) Serum levels of the Zonulin family of peptides in individuals from the PREVADIAB 2 cohort, a role in metabolic dysfunction. Diabetologia. 63 (Suppl 1): S217.

13. Meneses MJ, Pina A, Sousa-Lima I, Patarrão RS, Ribeiro RT, Gardete-Correia L, Duarte R, Boavida JM, Correia I, Andrade R, Medina JL, Raposo JF, Macedo MP (2020) Paraoxonase-1 como biomarcador no dismetabolismo: análise de clusters numa subpopulação do PREVADIAB2. Revista Portuguesa de Diabetes. 15(1)Suppl: 30.

12. Sousa-Lima I, Patarrão RS, Meneses MJ, Pina AF, Coelho M, Raposo JF, Ribeiro RT, Gardete-Correia L, Duarte R, Boavida JM, Correia I, Andrade R, Medina JL, Jones JG, Macedo MP (2020) Níveis séricos de péptidos da família da zonulina em indivíduos do PREVADIAB2. Revista Portuguesa de Diabetes. 15(1)Suppl: 65.

11. Meneses MJ, Sousa-Lima I, Borges DO, Patarrão RS, Raposo JF, Macedo MP (2019) A deleção da paraoxonase-1 agrava a intolerância à glicose causada por uma dieta hipercalórica. Revista Portuguesa de Diabetes. 14 (1) Suppl: 46.

10. Sousa-Lima I, Patarrão RS, Meneses MJ, Coelho M, Raposo JF, Ribeiro RT, Gardete-Correia L, Duarte R, Boavida JM, Correia I, Andrade R, Medina JL, Jones JG, Macedo MP (2018) Níveis Séricos de Zonulina em doentes com tolerância diminuída à glucose. Revista Portuguesa de Diabetes. 13 (1) Suppl:31.

9. Meneses MJ, Sousa-Lima I, Patarrão RS, Ribeiro RT, Gardete-Correia L, Duarte R, Boavida JM, Correia I, Andrade R, Medina JL, Raposo JF, Macedo MP (2018) Níveis Séricos de ApoJ/clusterina em doentes com tolerância diminuída à glucose. Revista Portuguesa de Diabetes. 13 (1) Suppl: 92.

8. Dias CG, Coelho NR, Grácio PC, Meneses MJ, Sousa-Lima I, Silva F, Serpa J, Soto K, Monteiro E, Macedo MP, Pereira SA (2018) Mercapturatos de dissulfetos de cisteína com marcadores de progressão de doença renal – comparação entre dois modelos animais de pré-diabetes. Revista Portuguesa de Diabetes. 13 (1) Suppl: 39.

7. Meneses MJ, Sousa-Lima I, Patarrão RS, Ribeiro RT, Gardete-Correia L, Duarte R, Boavida JM, Correia I, Andrade R, Medina JL, Jones JG, Raposo JF, Macedo MP (2018) ApoJ/clusterin serum levels in patients with impaired glucose tolerance. European Journal of Clinical Investigation 48: 63-64.

6. Meneses MJ, Borges DO, Dias TR, Martins FO, Oliveira PF, Macedo MP, Alves MG (2017) Diabetes e qualidade espermática: papel da enzima degradadora da insulina. Revista Portuguesa de Diabetes. 12(1) Suppl:38.

5. Meneses MJ, Sousa-Lima I, Ferreira I, Cruz H, Santos JM, Macedo MP (2017) Células Mesenquimais Estromais isoladas do cordão umbilical (UCX®): podem proteger contra a obesidade e esteatose hepática não-alcoólica? Revista Portuguesa de Cirurgia.

4. Meneses MJ*, Oliveira PF*, Martins AD, Monteiro MP, Sousa M, Silva BM, Alves MG (2016). Dietary habits and regulation of gut hormones levels have a major impact on male fertility. Acta Farmacêutica Portuguesa. 5(2):128-134.

3. Meneses MJ, Dias TR, Martins FO, Borges DO, Oliveira PF, Macedo MP, Alves MG (2016) “O Knock-out do gene que codifica a insulisina diminui a qualidade espermática de ratinhos” Acta Farmacêutica Portuguesa 5(2): pp. 115-120

2. Meneses MJ, Bernardino RL, Sá R, Silva J, Barros A, Sousa M, Silva BM, Oliveira PF, Alves MG (2015) The antidiabetic drug pioglitazone alters human Sertoli cells metabolism by increasing its glycolytic efficiency. Medicine J. 95(10):pe02371.

1. Meneses MJ, Bernardino RL, Sá R, Silva J, Barros A, Sousa M, Silva BM, Oliveira PF, Alves MG (2015). Os antidiabéticos Pioglitazona e Metformina alteram a cooperação metabólica testicular. CAPTAR 6(1): 47-48. ISSN: 1647-323X.

* both authors contributed equally

4. Meneses MJ (2017) Metabolic Disorders and Male Reproductive Health. In: Alves MG, Oliveira PF (eds) Biochemistry of Andrology, vol 1. Andrology: Current and Future Developments. Bentham Science Publishers, Sharjah, UAE, pp 326-359. ISBN: 978-1-68108-501-2

3. Meneses MJ, Martins AD (2017) Hormonal Control of Male Reproductive Function. In: Alves MG, Oliveira PF (eds) Biochemistry of Andrology, vol 1. Andrology: Current and Future Developments. Bentham Science Publishers, Sharjah, UAE, pp 126-153. ISBN: 978-1-68108-501-2

2. Moreira BP, Monteiro JP, Meneses MJ (2017) Testis Physiology. In: Alves MG, Oliveira PF (eds) Biochemistry of Andrology, vol 1. Andrology: Current and Future Developments. Bentham Science Publishers, Sharjah, UAE, pp 6-37. ISBN: 978-1-68108-501-2

1. Meneses MJ, Bernardino RL, Sousa M, Silva BM, Sá R, Oliveira PF, Alves MG (2015). Regulation of Testicular Glucose Metabolism in (Pre)Diabetes and its Implications to Male Reproductive Health. In Advances in Medicine and Biology. Volume 89. Nova Science Publishers, Inc, New York, USA, ISBN: 978-1-63483-478-0.

10. Pina AF, Borges DO, Meneses MJ, Branco P, Birne R, Vilasi A, Macedo MP (2020) Insulin: trigger and target of renal functions. Front Cell Dev Biol. 8:519. (doi: 10.3389/fcell.2020.00519)

9. Meneses MJ, Silvestre R, Sousa-Lima I, Macedo MP (2019). Paraoxonase-1 as a Regulator of Glucose and Lipid Homeostasis: Impact on the Onset and Progression of Metabolic Disorders. Int J Mol Sci 20: 4049. (doi: 10.3390/ijms20164049)

8. Candoso B, Meneses MJ, Alves MG, Sousa M, Oliveira PF (2019). Molecular aspects of collagenolysis associated with stress urinary incontinence in women with urethral hypermobility vs intrinsic sphincter deficiency. Neurourol Urodyn. 38: 1533‐ 1539. (doi: 10.1002/nau.24026)

7. Meneses MJ, Borges DO, Dias TR, Martins FO, Oliveira, PF, Macedo MP, Alves MG (2019). Knockout of insulin-degrading enzyme leads to mice testicular morphological changes and impaired sperm quality. Mol Cell Endocrinol. 486:11-17. (doi: 10.1016/j.mce.2019.02.011)

6. Borges DO*, Meneses MJ*, Dias TR, Martins FO, Oliveira PF, Alves MG, Macedo MP (2019) Data on metabolic profile of insulin-degrading enzyme knockout mice. Data in Brief (DOI:10.1016/j.dib.2019.104023)

5. Meneses MJ, Bernardino RL, Sá R, Silva J, Barros A, Sousa M, Silva BM, Oliveira PF, Alves MG (2016) Pioglitazone increases the glycolytic efficiency of human Sertoli cells with possible implications for spermatogenesis. Int J Biochem Cell Biol. 79:52-60 (DOI: 10.1016/j.biocel.2016.08.011)

4. Dias TR, Bernardino RL, Meneses MJ, Sousa M, Sá R, Alves MG, Silva BM, Oliveira PF (2016) Emerging potential of natural products as an alternative strategy to pharmacological agents used against metabolic disorders. Curr Drug Metab. 17(6): 582-597. (DOI: 10.2174/1389200217666160229113629)

3. Meneses MJ*, Rato L*, Silva BM, Sousa M, Alves MG, Oliveira PF (2015) New insights on hormones and factors that modulate Sertoli cell metabolism. Histol Histopathol 31(5):499-513 (DOI: 10.14670/HH-11-717)

2. Meneses MJ, Silva BM, Sousa M, Sá R, Oliveira PF, Alves MG (2015) Antidiabetic Drugs: mechanisms of action and potential outcomes on cellular metabolism. Curr. Pharm. Des. 21(25):3606-20 (DOI: 10.2174/1381612821666150710145753).

1. Meneses MJ, Sousa M, Alves MG, Oliveira PF (2015) The Antidiabetic Drug Metformin and Male Reproductive Function: An Overview. Int. J. Diab. Cardiov. Dis. Res. 3(1e): 1-2.

* both authors contributed equally