Luís Crisóstomo, Ph.D.

2021  – Best Pitch Talk at the Endopäivät 2021, The annual Congress of the Finnish Society of Endocrinology, 4th-5th November, Helsinki, Finland.

2021 – EMBO|EMBL Symposium Fee waiver for the virtual EMBO | EMBL Symposium: The Non-Coding Genome, 13th-15th October (Online)

2021 – Honourable Mention for Best Poster – WebRePRO - I Reproductive Sciences & Fertility Virtual Summit, 26th-27th July (Online). 

2021 – "FEBS Letters" Poster of the Day Award at the 45th FEBS congress (3-8 July 2021, Ljubljana, Slovenia) [online].

2020 – Fellowship to participate at the 20th FEBS Young Scientists’ Forum (1-4 July 2020, Lovran, Croatia) and at the 45th FEBS congress (4-9 July 2020, Ljubljana, Slovenia) [postponed to 2021].

2019 – Best Poster presentation at the 2nd Meeting of the 3rd Cycle in Biomedical Sciences of ICBAS-UP, 20th December 2019, Porto, Portugal.

2019 – Conference Grant , by the COST Action MitoEAGLE (CA15203), for attending the MiP 2019/MitoEAGLE Conference, 13-16 October 2019, at the University of Belgrade, Belgrade, Republic of Serbia.

2019 – Albert Renold Travel Fellowship Grant, by the European Foundation for the Study of Diabetes, Düsseldorf, Germany.

2018 – Trainee grant (Ref.: ECOST-TRAINING_SCHOOL-CA15203-211018-099045) for the MiPschool Tromsø-Bergen, 20-24 October, Hurtigruten: Tromsø - Bergen, Norway. 

2018 – ICDM Travel Grant for the ICDM 2018 Congress, 11-13 October, Grand Hilton Hotel, Seoul, South Korea. 

2018 – FEBS Congress Grant, the 43rd FEBS Congress, 7-12 July 2018, Prague Congress Centre, Prague, Czech Republic.

2018 – Best Poster in Fundamental Research, "High-fat diets compromise male fertility which is not recovered by diet reversion", the 14th Portuguese Congress of Diabetes, 9-11 March 2018, Hotel Tivoli Marina Vilamoura, Vilamoura, Portugal.

2017 – ITC Conference Grant (COST-ITCCG-CA15203-103), by the COST Action MitoEAGLE (CA15203), for attending the MiP 2017/MitoEAGLE Conference, 15-18 November 2017, at the Charles University - Faculty of Medicine, Hradec Králové, Czech Republic.

2017 – 4-year PhD fellowship (SFRH/BD/128584/2017), in the field of Clinical Medicine and Health Sciences by the Portuguese Foundation for Science and Technology (FCT).

2017 – MiPschool 2017 MITOEAGLE and MITOEAGLE workshop extended scholarship, for the 10th MiPschool and MITOEAGLE workshop, 23-30 July 2017, Universitätszentrum Obergurgl, Obergurgl Austria.

2017 – Grant "Nuno Castel-Branco" from Portuguese Society of Diabetology (SPD).

2013 – 3rd Prize - Best free presentation: training category, “Expression of Endogenous Antioxidants throughout a Sport Season”, the XXXVI APTN Technical-Scientific Congress, Guimarães, Portugal, 29-30 April 2013.

13. Crisóstomo L, Rato L, Jarak I, Videira RA, Starčević K, Mašek T, Raposo JF, Oliveira PF, Alves MG (2021). Ancestral paternal exposure to high-fat diets causes testicular metabolic and functional disturbances in mice up to two generations. FEBS Open Bio 11(S1), 501-502 (P-09.3-01 ).

12. Alves MG, Crisóstomo L, Rato L, Raposo JF, Oliveira PF (2021). A adoção de uma dieta rica em gordura pelo progenitor causa efeitos negativos na função e metabolismo testicular dos netos. 17º Congresso Português de Diabetes, 11-17 March (online meeting).

11. Crisóstomo L, Rato L, Raposo JF, Oliveira PF, Alves MG (2021). A exposição ancestral a dietas ricas em gordura promove um ambiente pro-inflamatório no testículo associado a defeitos espermáticos. 17º Congresso Português de Diabetes, 11-17 March (online meeting).

10. Crisóstomo L, Videira RA, Jarak I, Starčević K, Mašek T,  Rato L, Raposo JF, Batterham RL, Oliveira PF, Alves MG (2020) Prediabetes induces transgenerational effects in testicular metabolome and sperm quality: a silent comorbidity? Andrology. doi: 10.1111/andr.12930

9. Crisóstomo L, Videira RA, Jarak I, Starčević K, Mašek T,  Rato L, Raposo JF, Batterham RL, Oliveira PF, Alves MG (2020) Prediabetes induces transgenerational effects in testicular metabolome and sperm quality: a silent comorbidity? Journal of Reproductive Medicine and Endocrinology (in press)

8. Crisóstomo L, Videira RA, Jarak I, Starčević K, Mašek T,  Rato L, Raposo JF, Oliveira PF, Alves MG (2020) High-fat diet promotes a pro-inflammatory environment in mouse testes and inhibits certain antioxidant defenses in the testes of the progeny. Antioxidants. doi: 10.3390/CAHD2020-08623 

7. Crisóstomo L, Rato L, Jarak I, Videira R, Starčevic K, Mašek T, Raposo JF, Oliveira PF, Alves MG (2020) Permanent testicular metabolomic and lipidomic signatures induced by the adoption of a high-fat diet in childhood and sperm quality in adulthood. Human Reproduction; 35 Supp 1:169-170 (P-062)

6. Alves MG, Crisóstomo L, Videira RA, Rato L, Jarak I, Raposo JF, Oliveira PF (2020) A diabetes tipo 2 associada ao síndrome metabólico induzido por uma dieta rica em gordura promove alterações no metabolismo testicular dos descendentes. Revista Portuguesa de Diabetes; 15 (1) Supp: 94-107 (P110)

5. Alves MG, Crisóstomo L, Rato L, Jarak I, Silva BM, Raposo JF, Oliveira PF (2019) Uma dieta rica em gordura altera o metabolismo testicular o que compromete a qualidade reprodutiva. Revista Portuguesa de Diabetes; 14 (1) Supp:47-122 (P137)

4. Crisóstomo L, Rato L, Jarak I, Silva BM, Raposo JF, Oliveira PF, Alves MG (2019) Reversão da dieta rica em gordura para uma dieta normal, no início da idade adulta, previne a síndrome metabólica mas não melhora a qualidade espermática. Revista Portuguesa de Diabetes; 14 (1) Supp:23-26 (CO03)

3. Crisóstomo L, Rato L, Jarak I, Silva BM, Raposo JF, Oliveira PF, Alves MG (2018). High-fat diet compromise male fertility that is not surpassed by reversion to a controlled diet. FEBS Open Bio, 8: P.09-023-Tue. doi:10.1002/2211-5463.12453

2. Crisóstomo L, Rato L, Jarak I, Silva BM, Raposo JF, Oliveira PF, Alves MG (2018) Dietas gordas podem comprometer a fertilidade masculina que não é recuperada pelo regresso a uma dieta controlada. Revista Portuguesa de Diabetes; 13 (1) Supp:47-117 (P122)

1. Monteiro JP, Jesus TT, Crisóstomo L, Sousa M, Barros A, Oliveira PF, Alves MG (2017). mTOR coordinates the response to available energy substrates in human Sertoli cells: A defining point for male fertility? FEBS J. 284 (Suppl. 1): SpT.5.4-002. DOI: 10.1111/febs.14171

1. Crisóstomo L, Alves MG, Gorga A, Sousa M, Riera MF, Galardo MN, Meroni SB, Oliveira PF (2018) Molecular mechanisms and signalling pathways involved in the nutritional support of spermatogenesis by Sertoli cells. In: Alves MG, Oliveira PF (eds) Sertoli cells - Methods and Protocols. Methods in Molecular Biology, vol 1748, 1 edn. Humana Press, pp 129-155. DOI:10.1007/978-1-4939-7698-0 

Antioxidants - Guest Editor of the Special Issue "Antioxidants, Oxidative Stress and Non-Communicable Diseases"

Clinical Epidemiology (1179-1349)

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy (1178-7007)

Environmental International (0160-4120)

Frontiers in Cell and Developmental Biology (2296-634X)

Frontiers in Endocrinology (1664-2392)

International Journal of General Medicine (1178-7074)

Metabolites (2218-1989)

PLoS One (1932-6203 )

Reproductive Biology (1642-431X)

Reproductive Sciences (1933-7205)

Scientific Reports (2045-2322)

23. Pinto S, Guerra-Carvalho B, Crisóstomo L, Rocha A, Barros A, Alves MG, Oliveira PF. Metabolomics Integration in Assisted Reproductive Technologies for Enhanced Embryo Selection beyond Morphokinetic Analysis. International Journal of Molecular Sciences. 2024; 25(1):491. https://doi.org/10.3390/ijms25010491

22. Crisóstomo L, Oliveira PF, Alves MG. A systematic scientometric review of paternal inheritance of acquired metabolic traits. BMC Biol 21, 255 (2023). https://doi.org/10.1186/s12915-023-01744-6

21. Chaiyasoot K, Sakai NS, Zakeri R, Makaronidis J, Crisóstomo L, Alves MG, et al. Weight-loss Independent Clinical and Metabolic Biomarkers Associated with Type 2 Diabetes Remission Post-bariatric/metabolic Surgery. OBES SURG (2023). https://doi.org/10.1007/s11695-023-06905-8

20. Agarwal A, Cannarella R, Saleh R, Boitrelle F, Gül M, Toprak T, Salvio G, Arafa M, Russo GI, Harraz AM, Singh R, Garrido N, Hamoda TAAAM, Rambhatla A, Kavoussi P, Kuroda S, Çalik G, Saini P, Ceyhan E, Dimitriadis F, Henkel R, Crafa A, Palani A, Duran MB, Maziotis E, Saïs É, Bendayan M, Darbandi M, Le TV, Gunes S, Tsioulou P, Sengupta P, Hazir B, Çeker G, Darbandi S, Durairajanayagam D, Aghamajidi A, Alkhalidi N, Sogutdelen E, Leisegang K, Alarbid A, Ho CCK, Malhotra V, Finocchi F, Crisóstomo L, Kosgi R, ElBardisi H, Zini A, Birowo P, Colpi G, Park HJ, Serefoglu EC, Nguyen Q, Ko E, de la Rosette J, Pinggera GM, Nguyen HVP, Kandil H, Shah R (2022). Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis. World Journal of Men’s Health, 40. doi:10.5534/wjmh.220142

19. Crisóstomo L, Oliveira PF, Alves MG (2022). Antioxidants, Oxidative Stress, and Non-Communicable Diseases. Antioxidants, 11(6):1080. doi:10.3390/antiox11061080

18. Crisóstomo L, Bourgery M, Rato L, Raposo JF, Batterham RL, Kotaja N, Alves MG (2022). Testicular “inherited metabolic memory” of ancestral high-fat diet is associated with sperm sncRNA content. Biomedicines (Basel), 10(4):909. doi: 10.3390/biomedicines10040909

17. Agarwal A, Finelli R, Durairajanayagam D, Leisegang K, Henkel R, Salvio G, Aghamajidi A, Sengupta P, Crisóstomo L, Tsioulou PA, Roychoudhury S, Finocchi F, Darbandi M, Mottola F, Darbandi S, Iovine C, Santonastaso M, Zaker H, Kesari KK, Nomanzadeh A, Gugnani N, Rambhatla A, Duran MB, Ceyhan E, Kandil H, Arafa M, Saleh R, Shah Rupin, Boitrelle F (2022) Comprehensive Analysis of Global Research on Human Varicocele: A Scientometric Approach. World Journal of Men's Health, 40. doi:10.5534/wjmh.210202

16. Crisóstomo L, Videira RA, Jarak I, Starčević K, Mašek T, Rato L, Raposo JF, Batterham RL, Oliveira PF, Alves MG (2022) Inherited Metabolic Memory of High-fat Diet Impairs Testicular Fatty Acid Content and Sperm Parameters. Molecular Nutrition & Food Research, 2100680. doi:10.1002/mnfr.202100680

15. Guerra-Carvalho B*, Carrageta DF*, Crisóstomo L*, Carvalho RA, Alves MG, Oliveira PF (2021). Molecular mechanisms regulating spermatogenesis in vertebrates: Environmental, metabolic, and epigenetic factor effects. Animal reproduction science, 106896. doi:10.1016/j.anireprosci.2021.106896 

14. Crisóstomo L, Jarak I, Rato L, Raposo JF, Batterham RL, Oliveira PF, Alves MG (2021). Inheritable testicular metabolic memory of high-fat diet causes transgenerational sperm defects in mice. Scientific Reports, 11(1), 9444. doi:10.1038/s41598-021-88981-3 

13. Crisóstomo L, Oliveira PF, Alves MG (2021) Sperm, metabolic memory, and echoes from Lamarck. European Journal of Clinical Investigation. doi:10.1111/eci.13492

12. Pereira SC*, Crisóstomo L*, Sousa M, Oliveira PF, Alves MG (2020) Metabolic diseases affect male reproduction and induce signatures in gametes that may compromise the offspring health. Environmental Epigenetics, 6. doi:10.1093/eep/dvaa019

11. Crisóstomo L, Videira RA, Jarak I, Starčević K, Mašek T, Rato LP, Raposo JF, Batterham RL, Oliveira PF, Alves MG (2020) Diet during early life defines testicular lipid content and sperm quality in adulthood. American Journal of Physiology-Endocrinology & Metabolism 319: E1061–E1073. doi:10.1152/ajpendo.00235.2020

10. Crisóstomo L, Pereira SC, Monteiro MP, Raposo JF, Oliveira PF, Alves MG (2020) Lifestyle, metabolic disorders and male hypogonadism – A one-way ticket? Molecular and Cellular Endocrinology, 110945. doi: 10.1016/j.mce.2020.110945

9. Crisóstomo L, Rato L, Jarak I, Silva BM, Raposo JF, Batterham RL, Oliveira PF, Alves MG (2019) A switch from high-fat to normal diet does not restore sperm quality but prevents metabolic syndrome. Reproduction 158(4), 377–387. doi: 10.1530/REP-19-0259

8. Boussada M, Dias TR, Crisóstomo L, Akacha AB, Ali RB, El May MV, Alves MG, Oliveira PF (2019) A new thiocyanoacetamide (2-cyano-2-p-nitrophenyl-N-benzylthioamide) reduces doxorubicin-induced in vitro toxicity in Sertoli cells by decreasing apoptosis and autophagy. Theriogenology 140, 188-200. doi: 10.1016/j.theriogenology.2019.08.030

7. Crisóstomo L, Alves MG, Gorga A, Sousa M, Riera MF, Galardo MN, Meroni SB, Oliveira PF (2018) Molecular mechanisms and signalling pathways involved in the nutritional support of spermatogenesis by Sertoli cells. In: Alves MG, Oliveira PF (eds) Sertoli cells - Methods and Protocols. Methods in Molecular Biology, vol 1748, 1 edn. Humana Press, pp 129-155. doi:10.1007/978-1-4939-7698-0

6. Oliveira PF, Crisóstomo L, Sousa M, Monteiro MP, Macedo P, Raposo J, Alves MG (2017). O papel do Espermatozoide na Transmissão à Descendência do Risco para Diabetes Mellitus. [The Role of Sperm in the Transmission to the Offspring of the Risk for Diabetes Mellitus]. Revista Portuguesa de Diabetes. 12(4): 149-158.

5. Crisóstomo L, Alves MG, Calamita G, Sousa M, Oliveira PF (2017) Glycerol and testicular activity: the good, the bad and the ugly. Molecular Human Reproduction. 23(9), 583-655. doi: 10.1093/molehr/gax049

4. Costa AM, Grazina C, Miragaia D, Crisóstomo L, Carvalho PG (2017) Sports development environment in swimming clubs: a preliminary study on Portuguese swimmers' perceptions. Revista Iberoamericana de Psicología del Ejercicio y el Deport. 12(2), 231-236.

3. Crisóstomo L, Sousa M, Alves MG, Oliveira PF (2017) The Burden of Metabolic Diseases on Male Reproductive Health. International Journal of Diabetology & Vascular Disease Research. 5(1e), 1-2. doi: dx.doi.org/10.19070/2328-353X-1700012e

2. Casanova N, Palmeira-de-Oliveira A, Pereira A, Crisóstomo L, Travassos B, Costa AM (2016) Cortisol, testosterone and mood state variation during an official female football competition. The Journal of Sports Medicine and Physical Fitness, 56(6), 775-781.

1. Costa AM, Dias A, Crisóstomo L, Ramalhinho A, Breitenfeld L, Pereira A (2014) GlutathioneS-Transferase M1 and T1 genotypes in high-level swimmers: original research. International SportMed Journal, 15(4), 458-465.