Patrícia C. Braga, M.Sc.

PhD student

Supervision: Dr. Anabela Rodrigues (CHP)
Co-supervision: Prof. Marco G. Alves (ICBAS-UP)

patriciacbraga.1096@gmail.com
ORCID: 0000-0002-3813-8107

Short Biography

Patrícia Braga completed hers LSc degree on Applied Biology in 2017. In July of 2019 she finished hers MSc Degree on Applied Biochemistry, with specialization on Biomedicine at the University of Minho, Braga, Portugal. She joined the Sertoli Cell and Gamete Biology group in January 2019, to work on a research project aimed to elucidate the role of SIRT1 in Sertoli cells metabolism ,under supervision of Pedro F. Oliveira From 2020, she worked as a Laboratory Technician with a special interest on mitochondrial health in Sertoli cells and in Spermatozoa at the Institute of Biomedical Sciences Abel Salazar, University of Porto, Portugal. This year she enrolled the PhD programme on Biomedical Sciences, at the Biomedical Sciences Institute of Abel Salazar, University of Porto, Porto, Portugal (ICBAS-UP), under supervision of Anabela Soares Rodrigues and Marco G. Alves. Her research interest is the role of the mitochondria in Kidney disease.

Publications

10. Gomes-Andrade D, Guerra-Carvalho B, Carrageta DF, Bernardino RL, Braga PC, Oliveira PF, Pereira ML, Alves MG. Exposure to toxicologically relevant atrazine concentrations impair the glycolytic function of mouse Sertoli cells through the downregulation of lactate dehydrogenase, Toxicology and Applied Pharmacology, Volume 486, 2024. https://doi.org/10.1016/j.taap.2024.116929

9. Braga PC, Bernardino RL, Guerra-Carvalho B, Carrageta DF, Oliveira PF, Rodrigues AS, Alves MG. The progression from mild to severe hyperglycemia coupled with insulin resistance causes mitochondrial dysfunction and alters the metabolic secretome of epithelial kidney cells. Experimental Cell Research. 2023. 113744. https://doi.org/10.1016/j.yexcr.2023.113744

8. Luís C; Guerra-Carvalho B; Braga PC; Guedes C; Patrício E; Alves MG; Fernandes R; Soares R. The Influence of Adipocyte Secretome on Selected Metabolic Fingerprints of Breast Cancer Cell Lines Representing the Four Major Breast Cancer Subtypes. Cells 12,17. DOI: 10.3390/cells12172123

7. Costa J, Braga PC, Rebelo I, Oliveira PF, Alves MG. Mitochondria Quality Control and Male Fertility. Biology 12,6. DOI: 10.3390/biology12060827

6. Pereira PR, Pereira J, Braga PC, Pereira SS, Nora M, Guimarães M, Monteiro MP and Rodrigues AS. “Renal Dysfunction Phenotypes in Patients Undergoing Obesity Surgery”. Biomolecules. 13, 790. DOI: 10.3390/ biom13050790

5. Monteiro J, Marks CA, Braga PC, Bernardino RL, Alves MG, Lobo-da-Cunha A, Videira A, Pereira F. The role of ion homeostasis imbalance due to citrate accumulation in fluoroacetic acid (FAA) toxicity in Neurospora crassa. Comp Biochem Physiol C Toxicol Pharmacol. 2023 May 18;271:109661. doi: 10.1016/j.cbpc.2023.109661

4. Alves AP, Rocha SM, Mamede AC, Braga PC, Alves MG, Oliveira PF, Botelho FM, Maia CJ. Differential response of hepatocellular carcinoma glycolytic metabolism and oxidative stress markers after exposure to human amniotic membrane proteins. Mol Biol Rep. 2022 Aug;49(8):7731-7741. doi: 10.1007/s11033-022-07598-5

3. Braga, PC, Alves, MG, Rodrigues, AS, Oliveira, PF (2022). Mitochondrial Pathophysiology on Chronic Kidney Disease. Int. J. Mol. Sci. 23, 1776. doi:10.3390/ijms23031776

2. Ribeiro JC, Braga PC, Martins AD, Silva BM, Alves MG, Oliveira PF (2021). Antioxidants Present in Reproductive Tract Fluids and Their Relevance for Fertility. Antioxidants, 10(9), 1441. doi:10.3390/antiox10091441

1. Braga PC*, Pereira SC*, Ribeiro JC*, Sousa M, Monteiro MP, Oliveira PF, Alves MG. Late-Onset Hypogonadism and Lifestyle-Related Metabolic Disorders (2020) Andrology. doi:10.1111/andr.12765

*equal contribution