Bioinformatics Pilot Project Program
Request for Applications (RFA)
The goal of the SC INBRE Bioinformatics Pilot Project Program is to stimulate interest in the application of genomics and bioinformatics methods by supporting research and student training throughout the SC INBRE and South Carolina Clinical and Translational Research Institute (SCTR) networks. Funded projects are expected to generate preliminary data for presentations, publications and grant proposals by faculty and their students. All resulting publications must acknowledge SC INBRE support.
- Release Date: Friday, September 14, 2018 (revised September 28, 2018)
- Deadline for submission of application: Monday, December 3, 2018, 11:59 pm EST
- Period of performance: July 1, 2019 through June 30, 2020
Award amounts and number of anticipated awards:
Up to 8 awards of $10,000 each will be made.
Utilization of core facilities
If core facility support is required, projects should propose to work with one of the following INBRE-supported facilities:
- Microarray Facility at the University of South Carolina, Dr. Kim Creek, Director (Email, 803-777-0952)
- Proteogenomics Core Facility at the Medical University of South Carolina, Dr. Jeremy Barth, Director (Email, 843-792-9984)
- Instrumentation Resource Facility at the University of South Carolina School of Medicine, Dr. Bob Price, Director (Email, 803-733-3392)
- Computational, Data Storage and Analysis Facility at the University of South Carolina, Dr. Homayoun Valafar, Director (Email, 803-777-2404).
- NMR facility at Claflin University, Dr. Muthukrishna Raja (Email, 803-535-5673)
If the technical services required by the project cannot be provided by any of the listed facilities, or the project is based upon existing collaborations that already involve the use of other resources, it is acceptable to use other service providers, in or outside South Carolina.
Applicants must work with facility directors to plan the proposed experiments: a letter of support from the chosen facility’s Director or a quote (if using a commercial facility) must be included in the proposal.
Proposals are solicited from institutions of higher education in the SC INBRE network; affiliated members of SCTR; and interested students and faculty at primarily undergraduate institutions (PUI) across South Carolina.
Projects must be proposed and implemented by faculty and student teams, with a faculty member as PI and all other personnel as co-Investigators.
Only one proposal per funding period will be accepted from any faculty. Women, minorities and persons with disabilities are strongly encouraged to apply.
Proposal Preparation Instructions
Page Limits and Page Format
- The Project Description section of proposals must not exceed five pages in length.
- Proposals must be prepared with 1” margins, using Arial (or similar sans-serif font) and a font size no smaller than 11pt.
Assemble your application in the order listed below using the NIH form 398 forms available by clicking here. Please do not use any other forms than the NIH form 398 for the proposal face page, summary, budget and biosketch. Proposals that utilize other forms, including older forms from previous SC INBRE announcements, will be returned without review.
- Face page (NIH form 398, fp1)
- Project Summary/Abstract, performance sites, key personnel form (NIH form 398, fp2)
- Budget (NIH form 398, fp4)
- Budget justification
- Biosketch of key personnel (also in NIH format, form 398)
- Specific Aims (1 page)
- Research Plan (5 pages, maximum)
- Literature cited
- Plans for student training
- Human subjects (if applicable. IRB approval must be documented before the project can be approved by NIGMS)
- Vertebrate animals (if applicable. IACUC approval must be documented before the project can be approved by NIGMS)
- Biohazards (if applicable)
- Plans for further development of the work: Describe plans for publication and use of the data in grant proposals; specific opportunities for funding; anticipated new collaborations, etc.
A competitive proposal will describe a focused set of experiments that require bioinformatics methods of data analysis. The likelihood that the experiment proposed will yield data suitable for publication and usable as preliminary data for an extramural grant proposal will be one of the most important criteria for review. If the proposed research is translational in nature and/or you can foresee practical applications of the anticipated results, make sure to state that in the Significance and Innovation section.
All proposals that meet the eligibility requirements and guidelines will be independently evaluated by at least two external reviewers selected from a pool of individuals with suitable expertise, with the following review criteria:
- Scientific merit of the proposed project
- Potential to lead to a competitive extramural grant proposal, and potential for publication
- Qualifications of project personnel
- Appropriateness of budget
- Broader impact within the INBRE network, including involvement of underrepresented minorities within the research team: African-Americans, Pacific Islanders, Hispanics or Latinos, Native Americans, women, and/or persons with disabilities
Final decisions on funding will be made jointly by the SC INBRE Administrative Core, SC INBRE External Advisory Committee, and NIGMS.
Awards and Reporting Requirements
Principal Investigators will receive a notice of Pilot Project award/declination and copies of the reviewers’ comments via e-mail.
Award recipients are required to provide the SC INBRE state office with project data for evaluation and reporting purposes, as follows:
- A brief interim progress report, including an abstract summary of the supported activity, summary of expenditures, project plans for the future, and project achievements (publications, presentations, proposals submitted) is due by April 1, 2020.
- A comprehensive Pilot Project Progress Report is due by September 30, 2020.
- Final invoices for reimbursement must be received by August 1, 2020.
After the expiration of the award, SC INBRE will continue to contact the PI for outcome-related data such as grants, publications, etc. Failure to provide any requested materials for award or evaluation purposes will constitute default under this program, and disqualify the Pilot Project PI from further SC INBRE support.
Pilot Project Submission Instructions and Contact Information
Pilot project proposals, complete of required signatures on Certification and Budget pages, must be submitted as a single pdf file no later than Monday, December 3, 2018 by 11:59 pm EST, by email to firstname.lastname@example.org, with copy to John.Clarkson@uscmed.sc.edu.
Please direct any inquiries relating to this call for applications to John Clarkson, by email or by phone: (803) 216-3814