Publications

1. Prasad, H., Mandal, S., Mathew, J.K.K., Cherukunnath, A., Duddu, A.S., Banerjee, M., Ramani, H., Bhat, R., Jolly, M.K. and Visweswariah, S.S. (2024) An endosomal acid-regulatory feedback system rewires cytosolic cAMP metabolism and drives tumour progression. Mol. Cancer Res. (in press)

2. Mishra, V., Sharma, K., Bose, A., Maisonneuve, P. and Visweswariah S.S. (2023) The evolutionary divergence of receptor guanylyl cyclase C has implications for preclinical models for receptor-directed therapeutics. J Biol Chem. 300:105505.

3. Gupta K, Chakrabarti S, Janardan V, Gogia N, Banerjee S, Srinivas S, Mahishi D, Visweswariah SS. (2023)Neuronal expression in Drosophila of an evolutionarily conserved metallophosphodiesterase reveals pleiotropic roles in longevity and odorant response. PLoS Genet. 19:e1010962. doi:10.1371/journal.pgen.1010962

4. Shah IA, Prasad H, Banerjee S, Kurien RT, Chowdhury SD, Visweswariah SS. (2023) A novel frameshift mutation in TRPV6 is associated with hereditary pancreatitis. Front Genet. 9;13:1058057. doi: 10.3389/fgene.2022.1058057

5. Prasad H, Mathew J.K.K and Visweswariah, S.S. (2022) Receptor Guanylyl Cyclase C and Cyclic GMP in Health and Disease: Perspectives and Therapeutic Opportunities. Front Endocrinol. 13:911459. doi: 10.3389/fendo.2022.911459.eCollection 2022.

6. Sharma P, Vijaykumar A, Raghavan JV, Rananaware SR, Alakesh A, Bodele J, Rehman JU, Shukla S, Wagde V, Nadig S, Chakrabarti S, Visweswariah SS, Nandi D, Gopal B, Jhunjhunwala S. (2022) Particle uptake driven phagocytosis in macrophages and neutrophils enhances bacterial clearance. J Control Release 343: 131-141

7. Bose, A. and Visweswariah, S.S. (2022). The pseudokinase domain in receptor guanylyl cyclases. Methods Enzymol 667: 535-574.

8. Joshi, A., Visweswariah, S.S. and Chatterji, K. (2022). "Strategies to Promote Vascularization in 3D Printed Tissue Scaffolds: Trends and Challenges." Biomacromolecules 23: 2730-2751.

9. Chaukimath, P., Frankel, G. and Visweswariah, S.S. (2022). "The metabolic impact of bacterial infection in the gut. FEBS L. https://doi.org/10.1111/febs.16562

10. Mishra V., Bose A., Kiran S., Banerjee S., A Shah I., Chaukimath P., M Reshi M., Srinivas S., Barman A., Visweswariah S.S. (2021) Gut-associated cGMP mediates colitis and dysbiosis in a mouse model of an activating mutation in GUCY2C. J. Exp. Med. e20210479. doi: 10.1084/jem.20210479. "Correction: Gut-associated cGMP mediates colitis and dysbiosis in a mouse model of an activating mutation in GUCY2C." J Exp Med 218(11).

11. Chakraborti S., Chakraborty M., Bose A., Srinivasan N., Visweswariah, S.S. (2021) Identification of potential binders of Mtb universal stress protein (Rv1636) through an in silico approach and insights into compound selection for experimental validation. Front. Mol. Biosci. 8:599221. doi: 10.3389/fmolb.2021.599221

12. Prasad, H. and Visweswariah, S.S. (2021) Impaired intestinal sodium transport in inflammatory bowel disease: from the passenger to the driver's seat Cell. Mol. Gastro. Hepatol. 12: 277-292

13. Zaveri, A., Bose, A., Sharma, S., Rajendran, A., Biswas, P., Shenoy, A.R. and Visweswariah, S.S. (2021) Mycobacterial STAND adenylyl cyclases: the HTH domain binds DNA to form biocrystallized nucleoids Biophys. J. 120:1231-1246

14. Sathyanarayana, P., Visweswariah, S.S. and Ayappa, G. (2021) Mechanistic insighes into pore formation by an alpha-pore forming toxin: protein and lipid bilayer interactions of Cytolysin A. Acc Chem Res. 54: 120-131

15. Chakrabarti S and Visweswariah, S.S. (2020) Intramacrophage ROS primes the innate immune system via JAK/STAT and Toll activation. Cell Rep. 33: 108368

16. Bose, A., Banerjee, S. and Visweswariah, S.S. (2020) Mutational landscape of receptor guanylyl cyclase C: functional analysis and disease-related mutations. IUBMB Life 72: 1145-1159

17. Samanta, S., Biswas, P., Banerjee, A., Bose, A., Siddiqui, N., Nambi, S., Saini, DK and Visweswariah, S.S. (2020) A universal stress protein in Mycobacterium smegmatis sequesters the cAMP-regulated lysine acyltransferase and is essential for biofilm formation. J. Biol. Chem. 295:1500-1516

18. Prasad, H., Shenoy, A.R. and Visweswariah, S.S. (2020) Cyclic nucleotides, gut physiology and inflammation. FEBS J 287: 1970-1981.

19. Valantine, H., Travis, E., El-Adhami, W., Vernos, I., Mosqueda, L., Wayne, E., Kearns-Zimmerman., F, Bonefont., L, Visweswariah., SS, Akande-Sholabi, W. and Polka, J. (2019) A giant leap for woman kind. Nature. Med. 25: 704-707

20. Mishra, V., Goel, R. and Visweswariah, S.S. (2018) The kinase homology domain in receptor guanylyl cyclases: nothing ‘pseudo’ about it. Biochem. Soc. Trans. 46: 1729-1742 DOI: https://doi.org/10.1042/BST20180472

21. Sathyanarayana, P., Maurya, S., Behera, A., Ravichandran, M., Visweswariah, S.S., Ayappa, K.G. and Roy, R (2018) Cholesterol promotes Cytolysin A activity by stabilizing the intermediates during pore formation. Proc. Natl. Acad. Sci. (USA) 115: E7323-7330

22. Majumdar, S., Mishra, V., Nandi, S., Abdullah, M., Barman, A., Raghavan, A., Nandi, D. and Visweswariah, S.S. (2018) Absence of receptor guanylyl cyclase C enhances ileal damage and reduces cytokine and antimicrobial peptide production during oral Salmonella Typhimurium infection. Infect. Immun. 86: 799-817

23. Sharma, S and Visweswariah, SS (2017) Illuminating cyclic nucleotides: sensors for cAMP and cGMP and their applications in live cell imaging. J Ind. Inst. Sci. 97: 109-128

24. Samanta,S, Singh A, Biswas, P, Bhatt, A and Visweswariah SS (2017) Mycobacterial phenolic glycolipid synthesis is regulated by cAMP-dependent lysine acylation of FadD22 Microbiology 163: 373-382

25. Sathyanarayana P, Desikan,R, Ayappa, KG and Visweswariah, SS (2016) The Solvent-Exposed C-Terminus of the Cytolysin A Pore-Forming Toxin Directs Pore Formation and Channel Function in Membranes Biochemistry 55: 5952-5961

26. Bharambe, NG, Barathy, DV, Syed, W, Visweswariah, SS, Colaςo M, Colaςo S and Suguna K. (2016) Substrate specificity determinants of class III nucleotidyl cyclases The FEBS Journal 283: 3723-3738

27. Sarangi NK, Ayappa KG, Visweswariah SS, Basu JK (2016) Super-resolution Stimulated Emission Depletion-Fluorescence Correlation Spectroscopy Reveals Nanoscale Membrane Reorganization Induced by Pore-Forming Proteins Langmuir 32 : 9649-9657

28. Sarangi NK, Ayappa KG, Visweswariah SS, Basu JK (2016) Nanoscale dynamics of phospholipids reveals an optimal assembly mechanism of pore-forming proteins in bilayer membranes Physical Chemistry Chemical Physics 18 (43), 29935-29945

29. Singhal A, Arora G, Virmani R, Kundu P, Khanna T, Sajid A, Misra R, Joshi J, Yadav V, Samanta S, Saini N, Pandey AK, Visweswariah SS, Hentschker C, Becher D, Gerth U, Singh Y. (2015) Systematic Analysis of Mycobacterial Acylation Reveals First Example of Acylation-mediated Regulation of Enzyme Activity of a Bacterial Phosphatase. J Biol Chem. 290: 26218-34.

30. Visweswariah, S.S. and Busby, S.J. (2015) Evolution of bacterial transcription factors: how proteins take on new tasks, but do not always stop doing the old ones. Trends Microbiol. 23: 463-467.

31. Müller. T., Rasool, I., Heinz-Erian, P., Mildenberger, E., Hülstrunk, C., Müller, A., Michaud, L., Koot, B.G., Ballauff, A., Vodopiutz, J., Rosipal, S., Petersen, B.S., Franke, A., Fuchs, I., Witt, H., Zoller, H., Janecke, A.R. and Visweswariah, S.S. (2016) Congenital secretory diarrhoea caused by activating germline mutations in GUCY2C. Gut. 65: 1306-1313

32. Biswas, K.H., Badireddy, S., Rajendran, A., Anand, G.S., Visweswariah, S.S. (2015) Cyclic nucleotide binding and structural changes in the isolated GAF domain of Anabaena adenylyl cyclase, CyaB2. Peer J. 3:e882.

33. Barathy, D.V., Bharambe, N.G., Syed, W., Zaveri, A., Visweswariah, S.S., Colaςo, M., Misquith, S. and Suguna, K. (2015) Autoinhibitory mechanism and activity-related structural changes in a mycobacterial adenylyl cyclase. J. Struct. Biol. 190: 304-13.

34. Banerjee, A., Adolph, R.S., Gopalakrishnapai, J., Kleinboetling, S., Emmerich, C., Steegborn, C. and Visweswariah, S.S. (2015) A universal stress protein (USP) in Mycobacteria binds cAMP. J. Biol. Chem. 290: 12731-12743.

35. Matange, N., Podobnik, R. and Visweswariah, S.S. (2015) Metallophosphoesterases: structural similarity with functional promiscuity. Biochem. J. 467: 201-216.

36. Kumar, S., Matange, N., Umapathy, S. and Visweswariah, S.S. (2015) Linking carbon metabolism to carotenoid production in mycobacteria using Raman spectroscopy. FEMS Microbiol. Lett. 362: 1-6.

37. Pedroza-Roldán, C., Aceves-Sánchez, Mde, J., Zaveri, A., Charles-Niño, C., Elizondo-Quiroga, D.E., Hernández-Gutiérrez ,R., Allen, K., Visweswariah, S.S. and Flores-Valdez, M.A. (2015) The adenylyl cyclase Rv2212 modifies the proteome and infectivity of Mycobacterium bovis BCG. Folia Microbiol. 60: 21-31.

38. Wang, L., Zhang, X., Wang, G., Visweswariah, S.S., Lin, G., Xin, Z., Lue, T.F., Lin, C.S. (2015) Lobe-specific Expression of Phosphodiesterase 5 in Rat Prostate. Urology 85: 703.e7-e13.

39. Barathy, D., Mattoo, R., Visweswariah, S. and Suguna, K. (2014) New structural forms of a mycobacterial adenylyl cyclase Rv1625c. IUCrJ. 22: 338-348.

40. Kahramanoglou, C., Cortes, T., Matange, N., Hunt, D.M., Visweswariah, S.S, Young, D.B. and Buxton, R.S. (2014) Genomic mapping of cAMP receptor protein (CRP Mt) in Mycobacterium tuberculosis: relation to transcriptional start sites and the role of CRPMt as a transcription factor. Nucleic Acids Res. 42: 8320-8329.

41. Matange, N., Podobnik, M., Visweswariah. S.S. (2014) The non-catalytic "cap domain" of a mycobacterial metallophosphoesterase regulates its expression and localization in the cell. J. Biol. Chem. 289: 22470-22481.

42. Sharma, S., Zaveri, A., Visweswariah, S.S., Krishnan, Y. (2014) A fluorescent nucleic acid nanodevice quantitatively images elevated cyclic adenosine monophosphate in membrane-bound compartments. Small. 10: 4276-4280.

43. Sharma, R., Zaveri, A., Gopalakrishnapai, J., Srinath, T., Varshney, U., Visweswariah, S.S. (2014) Paralogous cAMP receptor proteins in Mycobacterium smegmatis show biochemical and functional divergence. Biochemistry 53: 7765-7776.

44. Podobink, M., Siddiqui, N., Rebolj, K., Nambi, S., Merzel, F. and Visweswariah, S.S. (2014) Allostery and conformational dynamics in cAMP-regulated acyltransferases. J. Biol. Chem. 289: 16588–16600.

45. Basu, N., Saha, S., Khan, I., Ramachandra, S.S. and Visweswariah, S.S.(2014) Intestinal cell proliferation and senescence is regulated by receptor guanylyl cyclase C and p21. J. Biol. Chem. 289: 581-593.

46. Vaidyanathan, M.S., Sathyanarayana, P. Maiti, P.K., Visweswariah, S.S. and Ayappa, K.G. (2014) Lysis dynamics and membrane oligomerizationpathways for Cytolysin A (ClyA) pore-forming toxin. RSC Adv, 4: 4930-4942.

47. Matange, N., Hunt, D.M., Buxton, R. S. and Visweswariah, S.S. (2013) Overexpression of the Rv0805 phosphodiesterase elicits a cAMP-independent transcriptional response. Tuberculosis 93: 492-500.

48. Nambi, S., Gupta, K., Bhattacharya, M., Ramakrishnan, P., Ravikumar, V., Siddiqui, N., Thomas, A.T. and Visweswariah, S.S. (2013) Cyclic AMP-dependent protein lysine acylation in mycobacteria regulates fatty acid and propionate metabolism. J. Biol. Chem. 288: 14114-14124.

49. Arshad, N. and Visweswariah. S.S. (2013) Cyclic nucleotide signaling in intestinal epithelia: getting to the gut of the matter. Wiley Interdiscip. Rev. Syst. Biol Med. J. 4: 409-424.

50. Arshad, N., Ballal, S. and Visweswariah, S.S. (2013) Site-specific N-Linked Glycosylation of Receptor Guanylyl Cyclase C Regulates Ligand Binding, Ligand-mediated Activation and Interaction with Vesicular Integral Membrane Protein 36, VIP36. J. Biol. Chem. 288: 3907-3917.

51. Arshad, N. and Visweswariah, S.S. (2012) The multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasis. FEBS Lett. 586: 2835-2840.

52. Nambi, S., BadiReddy, S., Visweswariah, S.S.# and Anand, G.S.,# (2012) Cyclic AMP-induced Conformational Changes in Mycobacterial Protein Acetyltransferases. J. Biol. Chem. 287: 18115-18129. # Corresponding Authors.

53. Fiskerstrand, T.,*# Arshad, N.,* Haukanes, B.I., Tronstad, R.R.,§ Pham, K.D., Johansson, S., Håvik, B., Tønder, S.L, Levy, S.E., Brackman, D., Boman, H., Biswas, K.H., Apold, J., Hovdenak, N., Visweswariah, S.S.# and Knappskog, P.M. (2012) Familial Diarrhea Syndrome caused by an activating GUCY2C activating mutation. N. Engl. J. Med.366: 1586-1595. *Joint first authors; # Corresponding Authors.

54. Dermol, U., Janardhan, V., Tyagi, R., Visweswariah, S.S.# and Podobnik, M.# (2011) Unique Utilization Of A Phosphoprotein Phosphatase (PPP) Fold By A Mammalian Phosphodiesterase Associated With The WAGR Syndrome. J. Mol. Biol. 412: 481-494 (# Corresponding Authors).

55. Chakraborti, P.K., Matange, N., Nandicoori, V.K., Singh, Y., Tyagi, J.S. and Visweswariah, S.S. (2011) Signaling Mechanisms in Mycobacteria. Tuberculosis 91: 432-440.

56. Basu, N. and Visweswariah, S.S. (2011) Defying the stereotype: non-canonical roles of the Peptide hormones guanylin and uroguanylin. Front. Endocrinol. 2, Article14: 1-5.

57. Biswas, K.H. and Visweswariah, S.S. (2011) Distinct allostery induced in the cyclic GMP-binding, cGMP-specific phosphodiesterase (PDE5) by cGMP, sildenafil and metal ions. J. Biol. Chem. 286: 8545-8554.

58. Nambi, S., Basu, N. and Visweswariah, S. S. (2010) Cyclic AMP-regulated protein lysine acetyl transferases in Mycobacteria. J. Biol. Chem. 285: 24313-24322.

Basu, N., Arshad, N. and Visweswariah, S.S. (2010) Receptor guanylyl Cyclase C (GC-C): Regulation and Signal Transduction Mol. Cell. Biochem.

60. Podobnik, M., Tyagi, R., Matange, N., Dermol, U., Gupta, A.K., Mattoo, R., Seshadri, K. and Visweswariah, S.S. (2009) A mycobacterial cyclic AMP phosphodiesterase that moonlights as a modifier of cell wall permeability J. Biol. Chem. 284: 32846–32857.

61. Basu, N., Bhandari, R., Tirumlai, V. and Visweswariah, S.S. (2009) Cross-talk between receptor guanylyl cyclase C and c-src tyrosine kinase regulates colon cancer cell cytostasis. Mol Cell. Biol. 29: 5277-5289 (Cover Page Image).

62. Saha, S., Biswas, K.H., Kondapalli, C., Isloor, N. and Visweswariah, S.S. (2009) The linker region in receptor guanylyl cyclases is a key regulatory module: mutational analysis of guanylyl cyclase C (GC-C) J. Biol. Chem. 284: 27135-27145.

63. Sawarkar, R., Visweswariah, S.S., Nellen, W. and Nanjundiah, V. (2009) Histone deacetylases regulate multicellular development in the social amoeba, Dictyosteliumdisciodeum. J. Mol. Biol. 391: 833-845.

64. Biswas, K.H., Shenoy, A.R., Dutta, A. and Visweswariah, S.S. (2009) The evolution of guanylyl cyclases as multidomain proteins: conserved features of kinase-cyclase domain fusions. J. Mol. Evol. 68: 587-602 (Cover Page Image).

65. Tyagi, R., Shenoy, A.R. and Visweswariah, S.S. (2009) Characterization of an evolutionary conserved metallophosphoesterase that is expressed in the fetal brain and associated with the WAGR syndrome. J. Biol. Chem. 284: 5217 – 5228.

66. Dass, B.K.M., Sharma, R., Shenoy, A.R., Mattoo, R. and Visweswariah, S.S. (2008) Cyclic AMP in Mycobacteria : Characterization and Functional Role of the Rv1647 Ortholog in Mycobacterium smegmatis. J. Bact. 190: 3824-3834.

67. Biswas, K.H., Sopory, S. and Visweswariah, S.S. (2008) The GAF domain of the cGMP-binding, cGMP-specific Phosphodiesterase (PDE5) is a sensor and a sink for cGMP. Biochemistry 47: 3534-3543.

68. Shenoy, A.R., Capuder, M., Draskovic, P., Lamba, D., Visweswariah, S.S. and Podobnik, M. (2007) Structural and Biochemical Analysis of the Rv0805 cyclic nucleotide phosphodiesterases from Mycobacterium tuberculosis. J. Mol. Biol. 365: 211-225.

69. Shenoy, A.R. and Visweswariah, S.S. (2006) New Messages from Old Messengers: cAMP and Mycobacteria. Trends Microbiol. 14: 543-550.

70. Shenoy, A.R. and Visweswariah, S.S. (2006) Mycobacterial adenylyl cyclases: Biochemical diversity and structural plasticity. FEBS Letters 580: 3344-3354.

71. Ketkar, A.D., Shenoy, A.R., Ramagopal, U.A., Visweswariah, S.S. and Suguna, K. (2006) A structural basis for the role of nucleotide specifying residues in regulating the oligomerization of the Rv1625c adenylyl cyclase from M. tuberculosis. J. Mol. Biol. 356: 904-916.

72. Jaleel, M., Saha, S., Shenoy, A.R. and Visweswariah, S.S. (2006) The kinase homology domain of receptor guanylyl cyclase C: ATP binding and identification of an adenine nucleotide sensitive site. Biochemistry. 45:1888-1898.

73. Shenoy A.R., Sreenath, N., Podobnik, M., Kovacevic, M., Visweswariah, S.S. (2005) The Rv0805 gene from Mycobacterium tuberculosis encodes a 3',5'-cyclic nucleotide phosphodiesterase: biochemical and mutational analysis. Biochemistry. 44: 15695-15704.

74. Shenoy, A.R., Sreenath, N.P., Mahalingam, M. and Visweswariah, S.S. (2005) Characterization of phylogenetically distinct members of the adenylate cyclase family from mycobacteria: Rv1647 from Mycobacterium tuberculosis and its orthologue ML1399 from M. leprae. Biochem. J. 387: 541-51.

75. Shenoy, A.R., Srinivas, A., Mahalingam, M. and Visweswariah, S.S.(2005) An adenylyl cyclase pseudogene in Mycobacterium tuberculosis has a functional ortholog in mycobacterium avium. Biochimie. 87: 557-563.

76. Jaleel, M., Shenoy, A,R. and Visweswariah, S.S. (2004) Tyrphostins are inhibitors of adenylyl and guanylyl cyclases. Biochemistry 43: 8247-8255.

77. Ghanekar, Y., Chandrashaker,A., Tatu, U. and Visweswariah, S.S. (2004) Glycosylation of the receptor guanylyl cyclase C: role in ligand binding and catalytic activity. Biochem. J. 379:1-11.

78. Shenoy, A.R. and Visweswariah, S.S. (2004) Class III nucleotide cyclases in bacteria and archaebacteria: lineage specific expansion of adenylyl cyclases and a dearth of guanylyl cyclases. FEBS Lett. Minireview 561: 11-21.

79. Shenoy, A.R., Sivakumar, Krupa, A., Srinivasan, N. and Visweswariah, S.S.(2004) A survey of nucleotide cyclases in Actinobacteria: unique domain organizations and expansion of the class III family in Mycobacterium tuberculosis. Comp. Funct. Genomics 5: 17-38.

80. Sopory, S., Kaur, T and Visweswariah, S.S. (2004) The cGMP-binding, cGMP-specific phosphodiesterase (PDE5): intestinal cell expression, regulation and role in fluid secretion. Cellular Signal. 16: 681-692.

81. Ketkar, A., Shenoy, A.R., Kesavulu, M.M., Visweswariah, S.S. and Suguna, K. (2004) Purification, crystallization and preliminary X-ray diffraction analysis of the catalytic domain of adenylyl cyclase Rv1625c from Mycobacterium tuberculosis. Acta Cryst. D. 60: 371-373.

82. Ghanekar, Y., Chandrashaker, A and Visweswariah, S.S. (2003) Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C. Eur. J. Biochem. 270: 3848-3857.

83. Shenoy, A.R. and Visweswariah, S.S. (2003) Site-directed mutagenesis using a single mutagenic oligonucleotide and DpnI digestion of template DNA Anal. Biochem. 319: 335-336.

84. Thomas, C.J., Sharma, S., Kunar, G., Visweswariah, S.S. and Surolia, A. (2003) Biopanning of endotoxin-specific phage displayed peptides. Biochem. Biophys. Res. Commun. 307: 133-138.

85. Shenoy, A.R., Srinivasan, N., Subramaniam, M and Visweswariah, S.S. (2003) Mutational analysis of the Rv1625c adenylyl cyclase: residues that confer nucleotide specificity contribute to dimerization. FEBS Lett. 542: 253-259.

86. Sopory, S., Balaji, S., Srinivasan, N. and Visweswariah, S.S. (2003) Modeling and mutational analysis of the GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase, PDE5. FEBS Lett. 539: 161-166.

87. Jaleel, M., London, R.M., Eber, S.L., Forte, L.R. and Visweswariah, S.S. (2002) Expression of the guanylyl cyclase C receptor and its ligands in reproductive tissues of the rat: a potential role for a novel signaling pathway in the epididymis. Biol. Reprod. 6: 1975-1980.

88. Sindic, A., Basoglu, C., Cetin, A., Hirsch, J.R., Potthast, R., Kuhn, M., Ghanekar, Y., Visweswariah, S.S. and Schlatter, E.R. (2002) Guanylin, uroguanylin and Sta activate guanylate-cyclase C and/or a PT-sensitive G protein in human proximal tubule cells. J. Biol. Chem. 277: 17758-17764.

89. Manjunath, U.H., Dalal, M., Chatterji, M., Radha, D.R., Visweswariah, S.S. and Nagaraja, V. (2002) Functional characterization of mycobacterial DNA gyrase: an efficient decatenase. Nucleic Acid Res. 30: 2144-2153.

90. Ghosh, Y.K. Visweswariah, S.S. and Bhattacharya, S. (2002) Advantage of the ether linkage between the positive charge and the cholestryl skeleton in cholesterol-based amphiphiles as vectors for gene delivery. Bioconjugate Chem. 13: 378-384.

91. Shenoy, A.R., Srinivasan, N. and Visweswariah, S.S. (2002) The ascent of nucleotide cyclases: conservation and evolution of a theme. J. Biosci. 27: 75-95.

92. Bhandari, R., Srinivasan, N., Mahaboobi, Ghanekar, Y., Suguna, K and Visweswariah, S.S. (2001) Functional inactivation of the human guanylyl cyclase C receptor: modeling and mutational analysis. Biochemistry 40: 9196-9206.

93. Roy, N., Guruprasad, M.R., Kondaiah, P., Mann, E.A. Giannella, R.A. and Visweswariah, S.S. Protein kinase C regulates transcription of the human guanylyl cyclase C gene. (2001) Eur. J. Biochem. 268: 2160-2171.

94. Manjunatha, U.H. Mahadevan, S., Visweswariah, S.S. and Nagaraja, V. (2001) Monoclonal antibodies to Mycobacterial DNA GyraseA inhibit DNA supercoiling activity. Eur. J. Biochem. 268: 2038-2046.

95. Bhandari, R., Mathew, R.. Vijayachandra, K. and Visweswariah, S.S. (2000) Tyrosine phosphorylation of the human guanylyl cyclase C receptor. J. Biosci. 25: 339-346.

96. Manjunatha, U.H., Somesh, B.P., Nagaraja, V. and Visweswariah, S.S. (2000) A Mycobacterium smegmatis gyraseB- specific monoclonal antibody reveals association of gyraseA and B subunits in the cell. FEMS Microbiol. Lett. 194: 87-92.

97. Vijayachandra, K., Guruprasad, M., Bhandari, R., Manjunath, U.H., Somesh, B.P., Srinivasan, N., Suguna, K. and Visweswariah, S.S. (2000) Biochemical characterization of the intracellular domain of the human guanylyl cyclase C receptor provided evidence for a catalytically active homotrimer. Biochemistry 39: 16075-16083.

98. Qian, X., Prabhakar, S., Nandi, A., Visweswariah, S.S. and Goy, M. (2000) Expression of GC-C, a receptor-guanylate cyclase, and its endogenous ligands uroguanylin and guanylin along the rostrocaudal axis of the intestine. Endocrinology 141: 3210-3224.

99. Manjunatha, U.H., Madhusudhana, K., Visweswariah, S.S. and Nagaraja, V. (2000) Structural heterogeneity in DNA gyrases. Current Sci. 79:968-974.

100. Ghosh, Y.K., Visweswariah, S.S. and Bhattacharya, S. (2000) Nature of linkage between the cationic headgroup and cholestryl skeleton controls gene transfection efficiency. FEBS Lett. 473: 341-344.

101. Bakre, M.M., Sopory, S. and Visweswariah, S.S. (2000) Expression and regulation of the cGMP-binding, cGMP-specific phosphodiesterase (PDE5) in human colonic epithelial cells: role in the induction of cellular refractoriness to the heat-stable enterotoxin peptide. J. Cell. Biochem. 77(1): 159-167.

102. Bakre, M.M., Ghanekar, Y. and Visweswariah, S.S. (2000) Homologous desensitization of the human guanylate cyclase C receptor Cell-specific regulation of catalytic activity. Eur. J. Biochem. 267(1): 179-187.

103. Bhandari, R. Suguna, K. and Visweswariah, S.S. (1999) Guanylyl cyclase C receptor: regulation of catalytic activity by ATP. Biosci. Rep. 19(3): 179-88.

104. Swaminathan, C.P., Nandi, A., Visweswariah, S.S. and Surolia, A (1999) Thermodynamic analyses reveal role of water release in epitope recognition by a monoclonal antibody against the human guanylyl cyclase C receptor. J. Biol. Chem. 274(44):31272-31278.

105. London, R.M., Eber, S.L., Visweswariah, S.S., Krause, W.J. and Forte, L.R. (1999) Structure and activity of OK-GC: a kidney receptor-guanylate cyclase activated by guanylin peptides. Am. Physiol. 276(6 Pt 2): F882-891.

106. Pattanaik, P., Sooryanarayana, Adiga, P.R. and Visweswariah, S.S. (1998) Refolding of native and recombinant chicken riboflavin carrier (or binding) protein:evidence for the formation of non-native intermediates during the generation of active protein. Eur. J. Biochem. 258: 411-418.

107. Nandi, A., Suguna, K., Surolia, A.A. and Visweswariah, S.S. (1998) Topological mimicry and epitope duplication in the guanylyl cyclase C receptor. Protein Sci. 7: 2175-2183.

108. Roy, N. and Visweswariah, S.S. (1998) Regulation of guanylyl cyclase C receptor activity by guanylin and protein kinase C. J. Biochem. Mol. Biol. Biophys. 2: 29-36.

109. Sooryanarayana, Sarkar, S., Adiga, P.R. and Visweswariah, S.S. (1997) Identification and characterisation of receptors for riboflavin carrier protein in the chicken oocyte. Role of the phosphopeptide in mediating receptor interaction. Biochim. Biophys. Acta 1382: 234-242.

110. Bakre, M.M. and Visweswariah, S.S. (1997) Dual Regulation of Heat-Stable Enterotoxin Mediated cGMP Accumulation in T84 cells by Receptor Desensitization and Increased Phosphodiesterase Activity. FEBS Lett. 408: 345-349.

111. Nandi, A., Bhandari, R. and Visweswariah, S.S. (1997) Epitope conservation and ImmunohistochemicalLocalisation of the Guanylin/Heat Stable Toxin Peptide Receptor, Guanylyl Cyclase C. J. Cellular Biochem. 66: 500-511.

112. Garrett, M.B. and Visweswariah, S.S. (1996) A conformational epitope in the N-terminus of heat-stable enterotoxins is involved in receptor-ligand interactions. Biochim. Biophys. Acta. 1317: 149-154.

113. Nandi, A., Roy, M. and Visweswariah, S.S. (1996) Expression of the extracellular domain of the human heat-stable enterotoxin receptor and generation of neutralising antibodies. Protein. Exp. Purifn. 8: 151-159.

114. Sooryanarayana, Adiga, P.R. and Visweswariah, S.S. (1996) Hyperexpression of chicken riboflavin carrier protein in E. coli: antibodies to the recombinant protein neutralise pregnancy in rodents. Prot. Expr. Purifn. 7: 147-154.

115. Visweswariah, S.S., Ramachandran, V., Ramamohan, S., Das, G. and Ramachandran, J. (1994) Characterisation and partial purification of the human receptor for the heat stable enterotoxin. Eur. J. Biochem. 219: 727-736.

116. Visweswariah, S.S., Shanthi, G. and Balganesh, T.S. (1992) Interaction of heat-stable enterotoxins with human colonic (T84) cells: modulation of the activation of guanylyl cyclase. Microb. Pathog. 12: 209-218.

117. Visweswariah, S.S., Shanthi, G. and Balganesh, T.S. (1990) Activation of guanylate cyclase in T84 human colonic cell line by heat-stable enterotoxins. (Rappuoli, R. et al Eds.) Bacterial Protein Toxins, ZBl. Bakt. Suppl 19: 285-286. Gustav Fischer, Stuttgart.

118. Dwarkanath, P., Visweswariah, S.S., Subrahmanyam, Y.V.B.K., Shanthi, G., Jagannatha, H.M. and Balganesh, T.S. (1989) Cloning and hyperexpression of a gene encoding the heat-stable enterotoxin of Escherichia coli. Gene81: 219-226.

119. Visweswariah, S.S. and Adiga, P.R. (1988) Estrogen modulation of riboflavin carrier protein in the bonnet monkey (M. radiata). J. Steroid Biochem. 31: 91-96.

120. Visweswariah, S.S. and Adiga, P.R. (1987) Isolation of riboflavin carrier proteins from pregnant human and umbilical cord serum. Similarities with chicken egg riboflavin carrier protein. Biosci. Rep. 7: 563-571.

121. Karande, A.A., Visweswariah, S.S. and Adiga, P.R. (1987) A rapid method of epitope analysis using Superose-12 gel filtration. A study using monoclonal antibodies to chicken riboflavin carrier protein. J. Immunol. Methods 99: 173-177.

122. Visweswariah, S.S., Karande, A.A. and Adiga, P.R. (1987) Immunological characterisation of riboflavin carrier proteins using monoclonal antibodies. Molec. Immunol. 24: 969-974.

123. Visweswariah, S.S. and Adiga, P.R. (1987) Purification of a circulatory riboflavin carrier protein from pregnant bonnet monkey (M. radiata). Comparison with the chicken egg vitamin carrier. Biochem. Biophys. Acta 915: 141-148.

124. Visweswariah, S.S., Prakash, G., Bhushan, V. and Chandrasekharan, S. (1982) One pot a-bromoketalisation of carbonyl compounds. Synthesis 4: 309-311.

Articles in Books.

1. Bakre,M.M. and Visweswariah,S.S. (1999) Molecular Mechanisms of Stable-Toxin mediated diarrhoeas . In Diarrhoeal Diseases: a research perspective (editor N. AppajiRao) Narosa Publishing House, New Delhi

2. Visweswariah, S.S. (2003) Diarrhoea due to Escherichia coli: Molecular aspects. In Diarrhoeal Diseases: Current status, research trends and field studies (Editors D. Raghunath and R. Nayak) Tata McGraw-Hill, New Delhi

3. Shenoy, A.R. and Visweswariah, S.S. (2004) Class III nucleotide cyclases in Bacteria: conservation and divergence of enzymes in Mycobacterium Tuberculosis. In Tuberculosis: Current Research Trends (Editor P. Sharma) Allied Publishers, New Delhi.

4. Basu, N. and Visweswariah, S.S. (2013) Guanylyl Cyclase C Encyclopedia of Signaling Molecules (S. Choi Ed) Springer 838-843

5. Arshad, N. and Visweswariah, S.S. (2013) Guanylyl Cyclase Receptors Encyclopedia of Signaling Molecules (S. Choi Ed) Springer 843-847

6. Mishra, V., Nandi, S. and Visweswariah, S.S. (2018) Guanylyl Cyclase C Encyclopedia of Signaling Molecules(S. Choi Ed) Springer https://doi.org/10.1007/978-3-319-67199-4_539

7. Visweswariah, S.S. and Jaiswal, N. (2018) Guanylyl Cyclase Receptors Encyclopedia of Signaling Molecules (S. Choi Ed) https://doi.org/10.1007/978-3-319-67199-4_434