The proposed microscope was integrated with an automatic imaging system and photoacoustics with contrast agents for studying tumor-immune interaction in a 3D cell culture system.

• Resolved optical alignment and synchronized a laser-scanning microscope system using LabVIEW

• Developed ultrasonic signal processing and image visualization algorithms using MATLAB

• Built protocols including contrast agents and 3D cell culture systems for the imaging system.

This work was to verify the feasibility of a Photoacoustic Angio-cam (PA-Cam) for subcutaneous vasculature imaging. The proposed PA-Cam was based on digicam-like photoacoustics, which was integrated with a pulse laser, acoustic lens, and 2D acoustic detection.

• Developed a 3D photoacoustic imaging system under the supervision of Meng-Lin Li, Ph.D.

• Assessed a 2D ultrasonic CMOS-sensor with collaborators