研究業績

AI-Generated Motifs Distinguish Altered Spatiotemporal Pain Response in the VTA of Mice with Chronic Pain.

Lloyd DA, Yao D, Ganaway A, Chen T, Ohta Y, Ohta J, Akay YM, Ohsawa M, Akay M.

IEEE J Biomed Health Inform. 2026 Jan 5;PP. doi: 10.1109/JBHI.2025.3650713. Online ahead of print.

Spinal Shati/nat8l regulates mechanical hyperalgesia through NAAG-mGluR3 signaling in neuropathic pain.

Miyamoto K, Tatsuta K, Sumi K, Uno K, Tokoro K, Muramatsu SI, Izuo N, Kume K, Nitta A, Ohsawa M*.

Neuropharmacology. 2025 Dec 31:110819. doi: 10.1016/j.neuropharm.2025.110819. Online ahead of print.

Sensing and Bio-Sensing Research A self-insertable 5- μ m-diameter flexible microneedle for minimally invasive and stable in vivo neural recording

Sasaki H, Shimizu S, Nerchan RV, Yamashita K, Takahashi N, Chinone R, Kurashige Y, Numano R, Koida K, Ohsawa M, Kawano T.

Sens Biosensing Res. 2025 doi.org/10.1016/j.sbsr.2025.100915. Online ahead of print.

AI-Based Localized Latent Neural Representations of Acute and Chronic Pain in Rats.

Yao D, Lloyd DA, Akay Y, Ohsawa M*, Akay M.

IEEE J Biomed Health Inform. 2025 Nov 3;PP. doi: 10.1109/JBHI.2025.3628226. Online ahead of print.

Hypothermia suppresses the hippocampal neuroinflammation in the mouse model of global cerebral ischemia–reperfusion injury.

Doshi M, Sakoori K, Chinone R, Ohsawa M, Natori Y, Ishii A, Watanabe S, Hosoyamada M, Hirashima-Aakae Y.

Discover Neuroscience 2025 doi: 10.1186/s13064-025-00200-1.

Mapping Morphine's Antinociceptive Impact on the Ventral Tegmental Area During Nociceptive Stimulation: A Novel Microimaging Approach in a Neuropathic Pain Model.

Ganaway A, Kamata A, Yao D, Sakoori K, Okada R, Chen T, Ohta Y, Ohta J, Ohsawa M, Akay M, Akay YM.

Int J Mol Sci. 2025 Jul 7;26(13):6526. doi: 10.3390/ijms26136526.

Exercise Suppresses Head and Neck Squamous Cell Carcinoma Growth via Oncostatin M.

Yoshimura T, Hirano Y, Hamada T, Yokoyama S, Suzuki H, Takayama H, Migita H, Ishida T, Nakamura Y, Ohsawa M, Asakawa A, Ishihata K, Tanimoto A.

Cancers (Basel). 2024 Mar 18;16(6):1187. doi: 10.3390/cancers16061187.

PMID: 38539521

Real-time monitoring of cortical brain activity in response to acute pain using wide-area Ca2+ imaging.

Inami C, Haruta M, Ohta Y, Tanaka M, So M, Sobue K, Akay Y, Kume K, Ohta J, Akay M, Ohsawa M*.

Biochem Biophys Res Commun. 2024 Mar 18;708:149800. doi: 10.1016/j.bbrc.2024.149800. Online ahead of print.

PMID: 38522402

Combined treatment with basalt stone and placenta extract to improve the chronic pain and scar after breast cancer surgery: a case report.

Inagaki M, Otsuka E, Hayashi Y, Ohsawa M, Hirano E.

J Med Case Rep. 2023 Dec 18;17(1):518. doi: 10.1186/s13256-023-04264-7.

PMID: 38105259

Investigating the Influence of Morphine and Cocaine on the Mesolimbic Pathway Using a Novel Microimaging Platform.

Ganaway A, Tatsuta K, Castillo VCG, Okada R, Sunaga Y, Ohta Y, Ohta J, Ohsawa M, Akay M, Akay YM.

Int J Mol Sci. 2023 Nov 14;24(22):16303. doi: 10.3390/ijms242216303.

PMID: 38003493

Reinstating olfactory bulb-derived limbic gamma oscillations alleviates depression-like behavioral deficits in rodents.

Li Q, Takeuchi Y, Wang J, Gellért L, Barcsai L, Pedraza LK, Nagy AJ, Kozák G, Nakai S, Kato S, Kobayashi K, Ohsawa M, Horváth G, Kékesi G, Lőrincz ML, Devinsky O, Buzsáki G, Berényi A.

Neuron. 2023 Jul 5;111(13):2065-2075.e5. doi: 10.1016/j.neuron.2023.04.013. Epub 2023 May 9.

PMID: 37164008 

Multi-Region Microdialysis Imaging Platform Revealed Dorsal Raphe Nucleus Calcium Signaling and Serotonin Dynamics during Nociceptive Pain.

Akbar L, Castillo VCG, Olorocisimo JP, Ohta Y, Kawahara M, Takehara H, Haruta M, Tashiro H, Sasagawa K, Ohsawa M, Akay YM, Akay M, Ohta J.

Int J Mol Sci. 2023 Apr 3;24(7):6654. doi: 10.3390/ijms24076654.

PMID: 37047627 

シンポジウム『伝統医学を科学する』「中枢神経系疾患に対する漢方薬の影響における基礎的エビデンス」　演者　第13回日本中医薬学会学術集会（2023年10月14日、東京） 

ランチョンセミナー『第65回日本老年医学会学術集会ランチョンセミナー』「筋力低下に対する人参養栄湯の可能性」　演者　第65回日本老年医学会学術集会（2023年6月16日、横浜） 

シンポジウム『痛み研究会2022招待講演　シンポジウム』「Modifications of pain perception by emotion and its mechanisms.」　座長兼演者　痛み研究会2022（2023年1月19日、愛知）