研究業績
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Research Papers & Reviews & Books
Research Papers & Reviews & Books
2024
Tanahashi, Y., Kitazawa, T., Unno, T. (2024). Muscarinic Regulation of Gastrointestinal Motility. In: Myslivecek, J., Jakubik, J. (eds) Muscarinic Receptor From Structure to Animal Models. Neuromethods, vol 211. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-4015-9_15
2023
Possible role of transient receptor potential melastatin 4 channels in adrenergic contractions in mouse prostate smooth muscles. Kiattisak PIMPJONG, Hayato MATSUYAMA, Taichi MIZUTANI, Yasuyuki TANAHASHI, Toshio OHTA, Toshihiro UNNO. J. Vet. Med. Sci., 85(7), pp.705-714 .
2021
Functions of Muscarinic Receptor Subtypes in Gastrointestinal Smooth Muscle: A Review of Studies with Receptor-Knockout Mice. Yasuyuki Tanahashi, Seiichi Komori, Hayato Matsuyama, Takio Kitazawa, and Toshihiro Unno. Int. J. Mol. Sci., 22(2), pp.926.
* The Top Downloaded Papers of IJMS in 2021 に選ばれました。
2020
Further characterization of the synergistic activation mechanism of cationic channels by M2 and M3 muscarinic receptors in mouse intestinal smooth muscle cells. Yasuyuki Tanahashi, Taisuke Katsurada, Noriko Inasaki, Mai Uchiyama, Takashi Sakamoto, Masayuki Yamamoto, Hayato Matsuyama, Seiichi Komori, and Toshihiro Unno. Am. J. Physiol. Cell Physiol., 318, pp.C514-C523.
2019
Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine. Hitomi Kimura, Yu-Ki Imura, Hirotaka Tomiyasu, Taiki Mihara, Noriyuki Kaji, Koichi Ohno, Toshihiro Unno, Yasuyuki Tanahashi, Tong-Rong Jan, Hirokazu Tsubone, Hiroshi Ozaki, Masatoshi Hori.Sci. Rep., 9(1), pp.5887.
Involvement of transient receptor potential melastatin 4 channels in the resting membrane potential setting and cholinergic contractile responses in mouse detrusor and ileal smooth muscles. Firoj ALOM, Hayato MATSUYAMA, Hiroshi NAGANO, Saki FUJIKAWA, Yasuyuki TANAHASHI, and Toshihiro UNNO. J. Vet. Med. Sci., 81(2), pp.217-228.
2018
Muscarinic suppression of ATP-sensitive K+ channels mediated by the M3/Gq/11/phospholipase C pathway contributes to mouse ileal smooth muscle contractions. B Wang, Y Murakami, M Ono, S Fujikawa, H Matsuyama, T Unno, K Naitou, Y Tanahashi. Am. J. Physiol. Gastrointest. Liver Physiol., 315(4), pp.G618-G630.
＊APS select September 2018に選ばれました。
Possible antagonistic effects of the TRPC4 channel blocker ML204 on M2 and M3 muscarinic receptors in mouse ileal and detrusor smooth muscles and atrial myocardium. F Alom, M Miyakawa, H Matsuyama, H Nagano, Y Tanahashi, T Unno. J. Vet. Med. Sci., 80(9), pp.1407-1415.
Muscarinic M2 receptor promotes vasopressin synthesis in mice supraoptic nuclei. Nagano H, Sobue Y, Matsuyama H, Saito S, Sakai H, Alom F, Tanahashi Y, Ishii T, Unno T. J. Endocrinol., 237(2), pp.207-216.
Before 2017
Before 2017
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels. HN Rubaiy, MJ Ludlow, M Henrot, HJ Gaunt, K Miteva, SY Cheung SY, Y Tanahashi, N Hamzah, KE Musialowski, NM Blythe, HL Appleby, MA Bailey, L McKeown, R Taylor, R Foster,H Waldmann, P Nussbaumer, M Christmann, RS Bon, K Muraki, DJ Beech. J. Biol. Chem., 292(20), pp.8158-8173 (2017).
Inhibitory effects of SKF96365 on the activities of K+ channels in mouse small intestinal smooth muscle cells. Y. Tanahashi, B. Wang, Y. Murakami, T. Unno, H. Matsuyama, H. Nagano and S. Komori. J. Vet. Med. Sci., 78(2), pp. 203–211 (2016).
A study on Borna disease virus infection in domestic cats in Japan. A. Someya, R. Fukushima, M. Yoshida, Y. Tanahashi, T. Prapeuk, R. Iizuka, H. Hirami, A. Matsuda, S. Takahashi, G. Kurita, T. Kimura, M. Seo, M. Funaba, Y. Nishino. J. Vet. Med. Sci., 76(8), pp. 1157-60 (2014).
Alveolar macrophage functions and DNA damage in cigarette smoke-exposed mice. Y. Hirono, Y. Tanahashi, K. Sasaki, K. Konno, Y. Shirai, K. Kobayashi, A. Someya, S. Inaga, M. Sakura, K. E. Pinkerton, M. Takeuchi. Advances in Bioscience and Biotechnology, 4, pp. 1-7 (2013).
Cholinergic neuromuscular transmission mediated by interstitial cells of Cajal in the myenteric layer inmouse ileal longitudinal smooth muscles. Yasuyuki Tanahashi, Yoshirou Ichimura, Kaori Kimura, Hayato Matsuyama, Satoshi Iino, Seiichi Komori, Toshihiro Unno. Naunyn-Schmiedeberg's Arch. Pharmacol., 387(4), pp. 377-388 (2013).
Evidence for M2 and M3 muscarinic receptor involvement in cholinergic excitatory junction potentials through synergistic activation of cation channels in the longitudinal muscle of mouse ileum. Hayato Matsuyama, Yasuyuki Tanahashi, Takio Kitazawa, Masahisa Yamada, Seiichi Komori,and Toshihiro Unno. Journal of Pharmacolological Sciences, 121(3),pp. 227-236 (2013).
Roles of M2 and M3 muscarinic receptors in the generation of rhythmic motor activity in mouse small intestine. Y. TANAHASHI, N. WAKI, T. UNNO, H. MATSUYAMA, S. IINO, T. KITAZAWA, M. YAMADA & S. KOMORI. Neurogastroenterology & Motility, Vol.25, e687–e697 (2013).
Muscarinic receptor subtypes mediating Ca2+ sensitization of intestinal smooth muscle contraction: studies with receptor knockout mice. Suguro M, Matsuyama H, Tanahashi Y, Unno T, Kitazawa T, Yamada M, Komori S. J. Vet. Med. Sci., 72(4),pp. 443-451 (2010).
Multiple muscarinic pathways mediate the suppression of voltage-gated Ca2+ channels in mouse intestinal smooth muscle cells. Tanahashi Y, Unno T, Matsuyama H, Ishii T, Yamada M, Wess J, Komori S. British Journal of Pharmacology, 158, pp. 1874–1883.
A non-selective cationic channel activated by diacylglycerol in mouse intestinal myocytes. Sakamoto T, Matsuyama H, Yamamoto M, Tanahashi Y, Kitazawa T, Taneike T, Komori S, Unno T. European Journal of Pharmacology, 599, pp. 54-57 (2008).
Muscarinic cationic current in gastrointestinal smooth muscles: signal transduction and role in contraction. Unno T, Matsuyama H, Okamoto H, Sakamoto T, Yamamoto M, Tanahashi Y, Yan HD, Komori S. Autonomic & Autacoid Pharmacology, 26, pp. 203-217 (2006).
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