Details on enteral formulas and additives and their use in patients with chronic kidney disease (CKD)
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Formulated for pediatric patients ≥1 year old
Has been shown to be safe in case studies as a fortifier for expressed breastmilk (EBM)
Can be alternative for Similac 60/40 or used for patients who have significant hyperkalemia issues despite decanting
Powder (unflavored), standard mixing 30 kcals/oz
Can be concentrated up to 2 kcals/mL (60 kcals/oz)
Usually dosed based on grams or scoops
Suitable for oral and tube feeding use
Unflavored: does not taste great but can be mixed in with other food products (e.g., used in baking)
Not suitable as a sole-source of nutrition
Used for supplemental feeds, added to food products, or as an additional ingredient in part of a feeding recipe with a more nutritionally complete formula with greater micronutrient content
Lower in protein, calcium, chloride, potassium, phosphorus and vitamin A compared to standard pediatric formulas
Made by Abbott
The only renal-specific infant formula
Suitable for birth-12 months or older if patient would benefit from additional catch-up growth
Infant formula has higher percentage of fat to more closely match breastmilk
Powder (unflavored), standard mixing 20 kcals/oz
Can be used as a fortifier for EBM
Suitable for oral and tube feeding use
Suitable as sole-source of nutrition
Lower in calcium, phosphorus, iron, sodium and potassium compared to standard pediatric formulas
Infants often still need decanting for potassium but often require phosphorus supplementation and iron supplementation
Made by Abbott
Ready-to-feed (RTF) liquid (vanilla), 54 kcals/oz (1.8 kcals/mL)
Can be used within 48 hours of opening as long as it is refrigerated
Vanilla flavor is used at LPCH as that is the best flavor for potassium and phosphorus content
Technically an adult formula
Designed for adult non-dialysis CKD patients
Lower in protein compared to Nepro, which tends to be a bit too high in protein for our pediatric patients
Can be used in pediatric patients ≥1 year old
Suitable for oral and tube feeidng use
Suitable as a sole-source of nutrition
Rare to be 100% of nutritional needs, typically because the volume required to meet their nutritional needs would exceed their maximum allowable vitamin A, so it is usually paired with additional formulas or modulators
Lower in potassium and phosphorus compared to standard formulas
Made by Abbott
RTF liqiuid, 54 kcals/oz (1.8 kcals/mL)
Vanilla flavor is used at LPCH as that is the best flavor for potassium and phosphorus content
Technically an adult formula
Designed for adult dialysis patients (higher in protein)
Can be used in pediatric patients ≥1 year old, however typically use in older/adolescent patients (≥12 years)
Suitable for oral and tube feeding use
Suitable as a sole-source of nutrition
Lower in potassium and phosphorus compared to standard formulas
Discontinued September 2022
Made by Nestle
RTF liquid (unflavored), 60 kcals/oz (2 kcals/mL)
Poorly tolerated as it is highly concentrated, so usually use as part of a recipe and typically will add free water unless necessary for fluid restriction
Technically an adult formula
Designed for adult AKI/CKD patients
Can be used in pediatric patients ≥1 year old
Suitable for tube feeding use
Technically can be used for oral feeding but rarely done
Not suitable as a sole-source of nutrition
High in calories, low in protein, higher MCT:LCT ratio
Some kids require higher MCT oil (e.g., fat malabsorption) - e.g., can be combined with Peptamen Jr 1.5
Very low in micronutrients (potassium, phosphorus, calcium, sodium, etc)
No fat-soluble vitamins
Used in recipes for patients who have a high vitamin A level, need concentrated feeds without too much protein
Made by Vitaflo
Formulated for pediatrics ≥1 year old
RTF (vanilla), 60 kcals/oz (2 kcals mL)
Suitable for oral and tube feeding use
Not suitable as a sole-source of nutrition
Lower in potassium, calcium, chloride, phosphorus, and vitamin A compared to standard pediatric formulas
Similar to Renalcal but has more DHA in it
Relatively new product so many not be available on hospital formularies
Intact, whey-based protein powder
Suitable for oral and tube feeding use
Not suitable as a sole-source of nutrition
Used for a child who needs additional protein and does not have milk protein allergy
Made by Nutricia
AA-based protein powder
Safe for patients with cow's milk allergy or multiple food allergies
Suitable for oral and tube feeding
Not suitable as a sole-source of nutrition
High calorie powder
Only contains CHO and fat
Safe for patients with cow's milk
Trace amounts of micronutrients but rarely causes issues unless given in excessive amounts
Suitable for oral and tube feeding use
Not suitable as a sole-source of nutrition
Unflavored (~7.7 kcals/mL)
For patients who are unable to digest or absorb conventional fats
MCTs are more readily hydrolyzed and absorbed than long chain fats
MCTs are absorbed directly into the portal circulation and do not require the bile salts for emulsification
Helpful for patients with fat malabsorption who struggle with other modulators like duocal
Suitable for oral and tube feeding use
Not suitable as sole source of nutrition
Administered alone, not mixed with formula
Hydrophobic, does not interact well with water
Emulsified for easier mixing
50% MCT/50% water
Can be mixed with formula or provided alone
May not be the best choice for someone who is very fluid restricted
Unflavored ~4.5 kcals/mL
For patients who are unable to digest or absorb conventional fats
MCTs are more readily hydrolyzed and absorbed than long chain fats
MCTs are absorbed directly into the portal circulation and do not require bile salts for emulsification
Suitable for oral and tube feeding use
Not suitable as a sole source of nutrition
Emulsified for easier mixing
50% MCT/50% water
Can be mixed with formula or provided alone
Microlipid has long chains
Avoided in chylothorax but either is a fine choice for the kidney population
For patients who are unable to digest or absorb conventional fats
MCTs are more readily hydrolyzed and absorbed than long chain fats
MCTs are absorbed directly into the portal circulation and do not require bile salts for emulsification
Suitable for oral and tube feeding use
Not suitable as a sole source of nutrition
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