Muscle Physiology Lab at UQTR

Skeletal muscle is a dynamic and essential tissue that plays a central role in movement, posture, and energy metabolism. Maintaining skeletal muscle mass and function is paramount for overall health and longevity. The JPLG Muscle Physiology lab is interested in studying the molecular and cellular mechanisms regulating skeletal muscle homeostasis. 

The JPLG Muscle Physiology lab focuses on studying signaling pathways that control protein breakdown and protein synthesis, with a particular emphasis on the discovery and characterization of novel autophagy genes. Autophagy, the catabolic process by which cells degrade their own components, is a fundamental cellular mechanism essential for maintaining muscle mass and function in both health and disease. My lab's primary goals is to identify and characterize novel regulators of autophagy, investigate the role of autophagy signaling in physiological and pathological conditions, and evaluate the therapeutic potential of autophagy modulation in treating skeletal muscle dysfunctions. Our research group employs a multidisciplinary approach that combines genetic, omic, molecular, cellular, and physiological approaches to investigate signaling pathways that regulate skeletal muscle health. 

The JPLG Muscle Physiology lab is part of Departement of medical biology at UQTR University. 

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