Dr. Jing Chen's Laboratory @ UChicago

Our Research

Our research aims to define how systemic metabolism regulates cancer and immunity. His laboratory has pioneered the discovery of signaling functions of circulating bioactive molecules, including nutrients, diet- and microbiota-derived metabolites, and neuroendocrine factors, that coordinate communication between peripheral organs, the immune system, and tumors. By elucidating how these circulating molecules reprogram immune-cell function and the tumor microenvironment, our research is uncovering new strategies for cancer prevention, immunotherapy, and precision nutrition.