Our projects
Ongoing projects:
2024-2028 Research project NCN OPUS 25 (2023/49/NZ1/00781) "Exploring unknown molecular mechanisms controlling ParB-dependent chromosome rearrangements in Streptomyces".
Principal investigator – M. Szafran
2024-2028 Research project NCN OPUS 25 (2023/49/B/NZ2/00356) "The interplay between nucleoid associated proteins and transcription factors at regulation of gene expression in antibiotic producing bacteria"
Principal investigator – D. Jakimowicz
2023-2027 Research project NCN OPUS 24 (2022/47/B/NZ1/00556) "Antibiotic discovery by induction of inactive antibiotic gene clusters"
Principal investigator – B. Kepplinger
2022-2025 Research project NCN SONATA 17 (2021/43/D/NZ2/00284) "Novel two-component system in Streptomyces and its role in growth regulation and mediating interspecies competition"
Principal investigator - M. Gongerowska-Jac
2021-2024: Research project NCN SONATA 16, (2020/39/D/NZ1/00303) “How cells of antibiotic-producing bacteria grow and branch?”
Principal investigator – B. Kepplinger
2021-2025: Research project NCN OPUS 19, (2020/37/B/NZ1/0055) “Chromosome architecture and translocation in asymmetrically growing and dividing Mycobacterium”
Principal investigator – J. Zakrzewska-Czerwińska
Ended projects:
2019-2022: Research project NCN OPUS 16, (2018/31/B/NZ1/00614) “Spatial organisation of Streptomyces chromosome during sporulation - impact on chromosome segregation, cell division, spores viability and germination”
Principal investigator – D. Jakimowicz
2019-2022: Research project NCN SONATA 14, (2018/31/D/NZ1/00287) “Two lysine posttranslational modifications, acetylation and pupylation and their role in regulation of Streptomyces chromosome topology”
Principal investigator – M. Szafran
2019-2022: Research project NCN OPUS 15, (2018/29/B/NZ6/00539) “Bdellovibrio bacteriovorus, a 'living antibiotic' - life cycle dynamics during predation on different pathogens”
Principal investigator – J. Zakrzewska-Czerwińska
2019-2020: Research project NCN Miniatura 3, (2019/03/X/NZ1/00280) “Global transcriptional analysis of AdpA-dependent genes in bacteria of Streptomyces genus in variable oxygen availability”
Principal investigator - M. Wolański
2018–2021: Research project NCN OPUS 14, (2017/27/B/NZ1/00823) "Mechanism of mycobacterial chromosome segregation - the role of proteins interacting with ParA"
Principal investigator - D. Jakimowicz
2018–2021: Research project NCN SONATINA 2, (2018/28/C/NZ1/00241) "Role of the interaction between HupA and HupS proteins during Streptomyces growth and stress response"
Principal investigator – A. Strzałka
2017–2020: Research project NCN OPUS 13, (2017/25/B/NZ1/00657) „Mycobacterial Lsr2 protein as a global chromosomal organizer and transcription factor – an interplay of Lsr2 with SMC complex and HupB"
Principal investigator – J. Zakrzewska-Czerwinska
2017–2020: Research project NCN HARMONIA 8, (2016/22/M/NZ1/00122) “The architecture of bacterial segrosome - the cooperation of topoisomerase I and segregation protein ParB in Streptomyces”
Principal investigator – M. Szafran
2017–2020: Research project NCN SONATINA 2, (2018/28/C/NZ1/00128) “mIHF, a unique mycobacterial nucleoid associated protein and its role in chromosome organization and gene expression”
Principal investigator – J. Hołówka
2015-2019: Research project NCN OPUS 8, (2014/15/B/NZ2/01067) “Chromosome topology as a global regulator of gene transcription - interplay between topoisomerases and nucleoid binding proteins in bacteria adaptation to stress conditions”
Principal investigator – D. Jakimowicz