Data Analysis and Survival for Personalised Oncology

Applied Statistics Research Group at the Mathematical Institute Leiden University


At DASPO we conduct high-quality quantitative research on survival analysis and related topics in the field of personalised oncology. We are active in the development of new methodologies for inference on the effectiveness of therapeutic regimens in fighting cancer. Our group is also interested in the correct application and adaptation of existing statistical techniques to an oncology setting.

The research group is active since June 2015, when the first project funded by KIKA started.

More about the group


DASPO is currently running two research projects financially supported by KIKA. These projects investigate the efficacy of chemotherapy regimens on survival outcome patients affected by osteosarcoma and acute lymphoblastic leukemia. Of particular interest are therapy modifications like delays and dose reductions induced by acute toxicity.

Another research project on personalised treatment for soft tissue sarcoma patients is under development with the financial support of KWF.

Overview of our research projects


DASPO closely collaborates with both national and international renown experts in the fields of medical oncology, clinical trials and biostatistics. DASPO's network provides the clinical expertise and the technical feedback to support all research activities of the group. Current collaborations include

National research institutes

Princess Maxima Center | LUMC | Radboud UMC | UMC Utrecht | AMC

International research institutes

Universitätsklinikum Essen | EORTC | MRC | UCLH

Clinical meetings we participated to

  • European Bone Sarcoma Network Meeting 2015
  • EMSOS Annual Meeting 2016
  • CTOS Annual Meeting 2016
  • Najaarscongres van de Nederlandse Orthopaedische Vereniging 2016
  • London Bone Sarcoma Meeting 2017
  • EMSOS Annual Meeting 2017
  • Ewing Spring Meeting 2018
  • EMSOS Annual Meeting 2018
  • 29th Annual Meeting of the International BFM Study Group
  • 19th congress of the European Federation of National Associations of Orthopedics and Traumatology


Mathematical Institute Leiden University

Niels Bohrweg 1, 2333CA, Leiden

daspo [at] math [dot] leidenuniv [dot] nl