バナー写真：山口県 下関市立しものせき水族館・海響館　Banner photo: Shimonoseki Aquarium / Kaikyokan, Shimonoseki , Yamaguchi

 論文

2024　　#  責任著者　Decision-making & Computational Psychiatry    Exercise    General Psychiatry & Psychology

Kosuke Hagiwara, Chong Chen#, Ryo Okubo, Sumiyo Okawa, Shin Nakagawa, Takahiro Tabuchi. (2024). Identifying distinct subtypes of mother-to-infant bonding using latent profile analysis in a nationwide Japanese study. Archives of Women's Mental Health, Published: 11 April 2024. fulltext

Tomohiro Mizumoto, Harumi Ikei, Kosuke Hagiwara, Toshio Matsubara, Fumihiro Higuchi, Masaaki Kobayashi, Takahiro Yamashina, Jun Sasaki, Norihiro Yamada, Naoko Higuchi, Kenichi Haraga, Fumiaki Kirihara, Emi Okabe, Kumi Asai, Masako Hirotsu, Chong Chen#, Yoshifumi Miyazaki, Shin Nakagawa. (2024). Mood and physiological effects of visual stimulation with images of the natural environment in individuals with depressive and anxiety disorders. Journal of Affective Disorders, 156, 257-266. fulltext

Chong Chen#, Sumiyo Okawa, Ryo Okubo, Kosuke Hagiwara, Tomohiro Mizumoto, Naoko Higuchi, Shin Nakagawa, Takahiro Tabuchi. (2024). Mother-to-infant bonding difficulties are associated with future maternal depression and child-maltreatment behaviors: A Japanese nationwide longitudinal study. Psychiatry Research, 334, 115814. fulltext

Chong Chen#, Kosuke Hagiwara, Shin Nakagawa (2024). Introducing the Chen-HAgiwara Mood Test (CHAMT): A novel, brief scale developed in Japanese populations for assessing mood variations. Asian Journal of Psychiatry, 93, 103941. fulltext

Chong Chen#, Yasuhiro Mochizuki, Sumiyo Okawa, Ryo Okubo, Shin Nakagawa, Takahiro Tabuchi (2024). Postpartum loneliness predicts future depressive symptoms: a nationwide Japanese longitudinal study. Archives of Women's Mental Health, Published: 27 January 2024. fulltext

Chong Chen#, Sumiyo Okawa, Ryo Okubo, Shin Nakagawa, Takahiro Tabuchi. (2024). Risk factors for persistent versus episodic mother-to-infant bonding difficulties in postpartum women in a nationwide Japanese longitudinal study. Journal of Affective Disorders, 349, 370-376. fulltext

Chong Chen#, Yasuhiro Mochizuki , Filipe M. Clemente. (2024). Editorial: Advances in the Understanding of the Affective and Cognitive Effects of Physical Activity, Exercise, and Sports. Frontiers in Psychology, 15, 1383947. fulltext

Chong Chen#. (2024). Exploring the impact of acute physical activity on creative thinking: A comprehensive narrative review with a focus on activity type and intensity. Discover Psychology, 4, 3. fulltext

Chihiro Kawashima, Chong Chen#, Kosuke Hagiwara, Tomohiro Mizumoto, Mino Watarai, Takaya Koga, Fumihiro Higuchi, Yuko Fujii, Emi Okabe, Shin Nakagawa. (2024). Evaluating the impact of a short bout of stair-climbing on creative thinking in a between-subjects pretest posttest comparison study. Scientific Reports, 14, 176. fulltext

Chong Chen#, Yasuhiro Mochizuki, Yoshiyuki Asai, Sumiyo Okawa, Ryo Okubo, Shin Nakagawa, Takahiro Tabuchi. (2024). Determining the optimal cutoff point for the Japanese Mother-to-Infant Bonding Scale: A data-driven approach. Asian Journal of Psychiatry, 19, 103874. fulltext

Chong Chen#, Ryo Okubo, Kosuke Hagiwara, Tomohiro Mizumoto, Shin Nakagawa, Takahiro Tabuchi. (2024). The association of positive emotions with absenteeism and presenteeism in Japanese workers. Journal of Affective Disorders, 344, 319-324. fulltext

2023

Chong Chen#, Sumiyo Okawa, Ryo Okubo, Shin Nakagawa, Takahiro Tabuchi. (2023). Risk factors for mother-to-infant bonding difficulties and maternal anger towards the infant in a Japanese longitudinal study. Asian Journal of Psychiatry, 89, 103778. fulltext

Chong Chen#, Shin Nakagawa. (2023). Recent advances in the study of the neurobiological mechanisms of the physical activity effects on mood, resilience, and emotional disorders. Advances in Clinical and Experimental Medicine, 32(9), 937-942. fulltext

Chong Chen#, Ryo Okubo, Sumiyo Okawa, Kosuke Hagiwara, Tomohiro Mizumoto, Naoko Higuchi, Shin Nakagawa, Takahiro Tabuchi. (2023). The prevalence and risk factors of suicidal ideation in women with and without postpartum depression. Journal of Affective Disorders, 340, 427-434. fulltext

Chong Chen#, Ryo Okubo, Sumiyo Okawa, Kosuke Hagiwara, Tomohiro Mizumoto, Naoko Higuchi, Shin Nakagawa, Takahiro Tabuchi. (2023). Broad impact of adverse childhood experiences on postpartum maternal mental health, child-rearing behaviors, and child development in Japan. Psychiatry and Clinical Neurosciences, 77, 569-571. fulltext

Masaru Tanaka , Chong Chen#. (2023). Editorial: Towards a Mechanistic Understanding of Depression, Anxiety, and Their Comorbidity: Perspectives from Cognitive Neuroscience. Frontiers in Behavioral Neuroscience, 17, 1268156. fulltext

Chong Chen#, Gabriele Nibbio, Yuka Kotozaki. (2023). Editorial: Methods and Applications in Psychopathology: New Methods and Trends for the Understanding of Neuropsychiatric Disorders. Frontiers in Psychology, 14, 1242921. fulltext

Chong Chen#, Ryo Okubo, Sumiyo Okawa, Shin Nakagawa, Takahiro Tabuchi. (2023). The diagnostic accuracy of the Edinburgh Postnatal Depression Scale without the self-harm item. Journal of Psychiatric Research, 165, 70-76. fulltext

Chong Chen#, Yuka Kotozaki, Ryo Okubo, Shin Nakagawa. (2023). Editorial: New Insights into Stress Coping and Resilience. Frontiers in Behavioral Neuroscience, 17, 1253170. fulltext

Mino Watarai , Kosuke Hagiwara , Yasuhiro Mochizuki , Chong Chen#, Tomohiro Mizumoto , Chihiro Kawashima , Takaya Koga , Emi Okabe , Shin Nakagawa. (2023). Toward a computational understanding of how reminiscing about positive autobiographical memories influences decision-making under risk. Cognitive, Affective, and Behavioral Neuroscience, 23, 1365-1373. fulltext

Chong Chen#, Ryo Okubo, Sumiyo Okawa, Naoko Higuchi, Shin Nakagawa, Takahiro Tabuchi. (2023). The prevalence and risk factors of suicidal ideation in pregnancy and the postpartum under the COVID‐19 pandemic in Japan. Psychiatry and Clinical Neurosciences, 77(5) 300-301. fulltext

Chong Chen#, Shin Nakagawa. (2023). Physical activity for cognitive health promotion: an overview of the underlying neurobiological mechanisms. Ageing Research Reviews, 86, 101868. fulltext

Takaya Koga, Ryo Okubo, Chong Chen#, Kosuke Hagiwara, Tomohiro Mizumoto, Shin Nakagawa, Takahiro Tabuchi. (2023). Associations of parent-child exercise with family relations and parental mental health during the COVID-19 pandemic. Journal of Affective Disorders, 324, 551-558. fulltext

Akiyoshi Shimura, Jiro Masuya, Katsunori Yokoi, Chihiro Morishita, Masayuki Kikkawa, Kazuki Nakajima, Chong Chen, Shin Nakagawa, Takeshi Inoue. (2023). Too much is too little: estimating the optimal physical activity level for a healthy mental state. Frontiers in Psychology, 13, 1044988. fulltext

Jun Sasaki, Toshio Matsubara, Chong Chen, Yuko Fujii, Yoko Fujita, Masako Nakamuta, Kumiko Nitta, Kazuteru Egashira, Takashi Hashimoto, Shin Nakagawa. (2023). Prefrontal activity during the emotional go/no-go task and computational markers of risk-based decision-making predict future relapse in alcohol use disorder. Frontiers in Psychiatry, 13, 1048152. fulltext

Hirotaka Yamagata, Ryouichi Tsunedomi, Toshiharu Kamishikiryo, Ayumi Kobayashi, Tomoe Seki, Masaaki Kobayashi, Kosuke Hagiwara, Norihiro Yamada, Chong Chen, Shusaku Uchida, Hiroyuki Ogihara, Yoshihiko Hamamoto, Go Okada, Manabu Fuchikami, Jun-ichi Iga, Shusuke Numata, Makoto Kinoshita, Takahiro A. Kato, Ryota Hashimoto, Hiroaki Nagano, Shuichi Ueno, Yasumasa Okamoto, Tetsuro Ohmori, Shin Nakagawa. (2023). Interferon signaling and hypercytokinemia-related gene expression in the blood of antidepressant non-responders. Heliyon, e13059. fulltext

2022 

陳 冲#, 中川 伸. (2022). The Exercise‐Glucocorticoid Paradoxからみた運動と脳機能. 日本生物学的精神医学会誌 33(4) 160-168. fulltext

Chong Chen#, Suk-Yu Yau, Filipe Manuel Clemente, Toru Ishihara. (2022). Editorial: The Effects of Physical Activity and Exercise on Cognitive and Affective Wellbeing. Frontiers in Behavioral Neuroscience, 16, 1047758. fulltext

Chong Chen# , Yasuhiro Mochizuki, Kosuke Hagiwara, Masako Hirotsu, Toshio Matsubara, Shin Nakagawa. (2022). Computational markers of experience- but not description-based decision-making are associated with future depressive symptoms in young adults. Journal of Psychiatric Research, 154, 307-314. fulltext

Natsumi Shimizu, Yasuhiro Mochizuki, Chong Chen#, Kosuke Hagiwara, Karin Matsumoto, Yusuke Oda, Masako Hirotsu, Emi Okabe, Toshio Matsubara, Shin Nakagawa.  (2022). The effect of positive autobiographical memory retrieval on decision-making under risk: a computational model-based analysis. Frontiers in Psychiatry, 13, 930466. fulltext

Toshio Matsubara, Chong Chen, Masako Hirotsu, Toshio Watanuki, Kenichiro Harada, Yoshifumi Watanabe, Koji Matsuo, Shin Nakagawa. (2022). Prefrontal cortex activities during verbal fluency and emotional words tasks in major depressive, adjustment, and bipolar disorders with depressive states. Journal of Affective Disorders, 316, 109-117. fulltext

Margret Shirinian, Chong Chen, Shusaku Uchida, Nafisa M Jadavji. (2022). Editorial: The role of epigenetics in neuropsychiatric disorders. Frontiers in Molecular Neuroscience, 15, 985023. fulltext

Chong Chen. (2022). Editorial: Recent advances in the study of the comorbidity of depressive and anxiety disorders. Advances in Clinical and Experimental Medicine, 31(4), 355-358. fulltext

Kosuke Hagiwara, Yasuhiro Mochizuki, Chong Chen#, Huijie Lei, Masako Hirotsu, Toshio Matsubara, Shin Nakagawa. (2022). Nonlinear probability weighting in depression and anxiety: insights from healthy young adults. Frontiers in Psychiatry, 13, 810867. fulltext

Huijie Lei, Chong Chen#, Kosuke Hagiwara, Ichiro Kusumi, Hajime Tanabe, Takeshi Inoue, Shin Nakagawa. (2022). Symptom patterns of the occurrence of depression and anxiety in a Japanese general adult population sample: a latent class analysis. Frontiers in Psychiatry, 13, 808918. fulltext

Karin Matsumoto, Chong Chen#, Kosuke Hagiwara, Natsumi Shimizu, Masako Hirotsu, Yusuke Oda, Huijie Lei, Akiyo Takao, Yuko Fujii, Fumihiro Higuchi, Shin Nakagawa. (2022). The effect of brief stair-climbing on divergent and convergent thinking. Frontiers in Behavioral Neuroscience, 15, 834097. fulltext

2021 

Yuri Sakai, Chong Chen#, Atsuhito Toyomaki, Naoki Hashimoto, Kan Kitagawa, Takao Inoue, Asumi Sato, Keisuke Makihara, Rie Kameyama, Yumi Wakatsuki, Niki Udo, Ryosuke Shirakawa, Takashi Yokota, Shin Nakagawa, Ichiro Kusumi. (2021). A brief, individualized exercise program at intensities below the ventilatory threshold exerts therapeutic effects for depression: a pilot study. Frontiers in Behavioral Neuroscience, 15, 787688. fulltext

Hirotaka Yamagata, Ayumi Kobayashi, Ryouichi Tsunedomi, Tomoe Seki, Masaaki Kobayashi, Kosuke Hagiwara, Chong Chen, Shusaku Uchida, Go Okada, Manabu Fuchikami, Toshiharu Kamishikiryo, Jun-ichi Iga, Shusuke Numata, Makoto Kinoshita, Takahiro A. Kato, Ryota Hashimoto, Hiroaki Nagano, Yasumasa Okamoto, Shuichi Ueno, Tetsuro Ohmori, Shin Nakagawa. (2021). Optimized protocol for the extraction of RNA and DNA from frozen whole blood sample stored in a single EDTA tube. Scientific Reports, 11, 17075. fulltext

Chong Chen#, Yasuhiro Mochizuki, Kosuke Hagiwara, Masako Hirotsu, Shin Nakagawa. (2021). Regular vigorous-intensity physical activity and walking are associated with divergent but not convergent thinking in Japanese young adults. Brain Sciences, 11(8), 1046.  fulltext

Rikuto Yamashita, Chong Chen#, Toshio Matsubara, Kosuke Hagiwara, Masato Inamura, Kohei Aga, Masako Hirotsu, Tomoe Seki, Akiyo Takao, Erika Nakagawa, Ayumi Kobayashi, Yuko Fujii, Keiko Hirata, Harumi Ikei, Yoshifumi Miyazaki, Shin Nakagawa. (2021). The mood-improving effect of viewing images of nature and its neural substrate. International Journal of Environmental Research and Public Health, 18(10), 5500. fulltext

Kohei Aga, Masato Inamura, Chong Chen#, Kosuke Hagiwara, Rikuto Yamashita, Masako Hirotsu, Tomoe Seki, Akiyo Takao, Yuko Fujii, Toshio Matsubara, Shin Nakagawa. (2021). The effect of acute aerobic exercise on divergent and convergent thinking and its influence by mood. Brain Sciences, 11(5), 546. fulltext

Huijie Lei, Yasuhiro Mochizuki, Chong Chen#, Kosuke Hagiwara, Masako Hirotsu, Toshio Matsubara, Shin Nakagawa. (2021). Sex difference in the weighting of expected uncertainty under chronic stress. Scientific Reports, 11, 8700. fulltext

Ibuki Koan, Takumi Nakagawa, Chong Chen#, Toshio Matsubara, Huijie Lei, Kosuke Hagiwara, Masako Hirotsu, Hirotaka Yamagata, Shin Nakagawa. (2021). The negative association between positive psychological wellbeing and loss aversion. Frontiers in Psychology, 12:641340. fulltext

Hirotaka Yamagata, Hiroyuki Ogihara, Koji Matsuo, Shusaku Uchida, Ayumi Kobayashi, Tomoe Seki, Masaaki Kobayashi, Kenichiro Harada, Chong Chen, Shigeo Miyata, Masato Fukuda, Masahiko Mikuni, Yoshihiko Hamamoto, Yoshifumi Watanabe, Shin Nakagawa. (2021). Distinct epigenetic signatures between adult-onset and late-onset depression. Scientific Reports, 11, 2296. fulltext

Toshio Matsubara, Naoki Yamamoto, Chong Chen, Shigeru Okuya, Shin Nakagawa. (2021). A 26-year retrospective survey on suicide cases of students at Yamaguchi University (1992–2017): Risk factors and the role of the health administration center. Psychiatry Research, 295, 113566. fulltext

2020

萩原 康輔, 陳 冲#, 中川 伸. (2020). 情報処理理論からみたうつ病における認知障害−Hot vs. cold cognition−. 精神科, 37(3), 291-296. fulltext

Takumi Nakagawa, Ibuki Koan, Chong Chen#, Toshio Matsubara, Kosuke Hagiwara, Huijie Lei, Masako Hirotsu, Hirotaka Yamagata, Shin Nakagawa. (2020). Regular moderate- to vigorous-intensity physical activity rather than walking is associated with enhanced cognitive functions and mental health in young adults. International Journal of Environmental Research and Public Health, 17(2), 614-614. fulltext

2019

Tomoe Seki, Hirotaka Yamagata, Shusaku Uchida, Chong Chen, Ayumi Kobayashi, Masaaki Kobayashi, Kenichiro Harada, Koji Matsuo, Yoshifumi Watanabe, Shin Nakagawa. (2019). Altered expression of long noncoding RNAs in patients with major depressive disorder. Journal of Psychiatric Research, 117,92-99.

2018

Chong Chen#, Shin Nakagawa. (2018). Planetary health and the future of human capacity: the increasing impact of planetary distress on the human brain. Challenges, 9(2), 41. fulltext

Okubo R, Chen C, Sekiguchi M, Hamazaki K, Matsuoka YJ . (2018). Mechanisms underlying the effects of n-3 polyunsaturated fatty acids on fear memory processing and their hypothetical effects on fear of cancer recurrence in cancer survivors. Prostaglandins, Leukotrienes and Essential Fatty Acids, 131, 14-23.

2017

Chong Chen, Shin Nakagawa, Yan An, Koki Ito, Yuji Kitaichi, Ichiro Kusumi. (2017). The exercise-glucocorticoid paradox: How exercise is beneficial to cognition, mood, and the brain while increasing glucocorticoid levels. Frontiers in Neuroendocrinology, 44, 83-102. fulltext

2016

Yan An, Chong Chen*, Takeshi Inoue, Shin Nakagawa, Yuji Kitaichi, Ce Wang, Takeshi Izumi, Ichiro Kusumi. (2016). Mirtazapine exerts an anxiolytic-like effect through activation of the median raphe nucleus-dorsal hippocampal 5-HT pathway in contextual fear conditioning in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 70, 17-23.  * co-first author fulltext

Chong Chen, Shin Nakagawa, Yuji Kitaichi, Yan An, Yuki Omiya, Ning Song, Minori Koga, Akiko Kato, Takeshi Inoue, Ichiro Kusumi. (2016). The role of medial prefrontal corticosterone and dopamine in the antidepressant-like effect of exercise. Psychoneuroendocrinology, 69, 1-9. fulltext

Yan An, Takeshi Inoue, Yuji Kitaichi, Chong Chen, Shin Nakagawa, Ce Wang, Ichiro Kusumi. (2016). Combined treatment with subchronic lithium and acute intracerebral mirtazapine microinjection into the median raphe nucleus exerted an anxiolytic-like effect synergistically. European Journal of Pharmacology, 783, 112-116. fulltext

2015

Yukiei Nakai, Takeshi Inoue, Chong Chen, Hiroyuki Toda, Atsuhito Toyomaki, Yasuya Nakato, Shin Nakagawa, Yuji Kitaichi, Rie Kameyama, Yumi Wakatsuki, Kan Kitagawa, Hajime Tanabe, Ichiro Kusumi. (2015). The moderator effects of affective temperaments, childhood abuse and adult stressful life events on depressive symptoms in the nonclinical general adult population. Journal of Affective Disorders, 187, 203-210. fulltext

Chong Chen#, Yuki Omiya, Si Yang. (2015). Dissociating contributions of ventral and dorsal striatum to reward learning. Journal of Neurophysiology, 114(3) 1364-1366. fulltext

Chong Chen#, Taiki Takahashi, Shin Nakagawa, Takeshi Inoue, Ichiro Kusumi. (2015). Reinforcement learning in depression: A review of computational research. Neuroscience & Biobehavioral Reviews, 55(21), 247-267. fulltext

Chong Chen. (2015). Intelligence moderates reinforcement learning: a mini-review of the neural evidence.  Journal of Neurophysiology, 113(10), 3459-3461. fulltext

Chong Chen#, Taiki Takahashi, Si Yang. (2015). Remembrance of happy things past: positive autobiographical memories are intrinsically rewarding and valuable, but not in depression. Frontiers in Psychology, 6, 222. fulltext

Yan An, Takeshi Inoue, Yuji Kitaichi, Shin Nakagawa, Ce Wang, Chong Chen, Ning Song, Ichiro Kusumi. (2015). Subchronic lithium treatment increases the anxiolytic-like effect of mirtazapine on the expression of contextual conditioned fear. European Journal of Pharmacology, 747, 13-17. fulltext

2014

Chong Chen#, Yuki Omiya. (2014). Brain asymmetry in cortical thickness is correlated with cognitive function. Frontiers in Human Neuroscience, 8, 877. fulltext

Yuji Kitaichi, Takeshi Inoue, Shin Nakagawa, Yuki Omiya, Ning Song, Yan An, Chong Chen, Ichiro Kusumi, Tsukasa Koyama. (2014).Local infusion of citalopram into the basolateral amygdala decreased conditioned fear of rats through increasing extracellular serotonin levels. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 54, 216-222.

2013

Yan An, Takeshi Inoue, Yuji Kitaichi, Takeshi Izumi, Shin Nakagawa, Ning Song, Chong Chen, Xiaobai Li, Tsukasa Koyama, Ichiro Kusumi. (2013). Anxiolytic-like effect of mirtazapine mediates its effect in the median raphe nucleus. European Journal of Pharmacology, 720(1-3), 192-197. fulltext

著書

Chong Chen, Yasuhiro Mochizuki, Filipe Manuel Clemente. (2024). Advances in the Understanding of the Affective and Cognitive Effects of Physical Activity, Exercise, and Sports. Lausanne, Switzerland: Frontiers Media SA 2024年3月 (ISBN: 9782832546635). fulltext

Chong Chen, Gabriele Nibbio, Yuka Kotozaki. (2023). Methods and Applications in Psychopathology: New Methods and Trends for the Understanding of Neuropsychiatric Disorders. Lausanne, Switzerland: Frontiers Media SA 2023年8月 (ISBN: 9782832531600). fulltext

Chong Chen, Yuka Kotozaki, Ryo Okubo, Shin Nakagawa. (2023). New Insights into Stress Coping and Resilience. Lausanne, Switzerland: Frontiers Media SA. 2023年7月(ISBN: 9782832531082). fulltext

Chong Chen, Suk-Yu Yau, Filipe Manuel Clemente, Toru Ishihara. (2022). The Effects of Physical Activity and Exercise on Cognitive and Affective Wellbeing. Lausanne, Switzerland: Frontiers Media SA. 2022年12月(ISBN: 9782832508145). fulltext

陳 冲, 望月 泰博. (共著). 頭を良くしたければ体を鍛えなさい : 脳がよろこぶ運動のすすめ .東京：中央公論新社. 2020年1月20日 (ISBN: 9784120052606). 出版社ページ　Amazon.co.jp

Chong Chen, Shin Nakagawa. Nature’s Pathways on Human Health. Dieter Kotte, Qing Li, Won Sop Shin, Andreas Michalsen, editors. International Handbook of Forest Therapy (pp. 12-31). Newcastle upon Tyne, UK: Cambridge Scholars Publishing. 2019年12月 (ISBN: 9781527539556). fulltext

望月泰博, 陳冲, 福田玄明, 中原裕之. 報酬予測.  日本神経科学学会 脳科学辞典 2018年3月(DOI：10.14931/bsd.7486). fulltext

Chong Chen, Taiki Takahashi. Reward processing in depression: the computational approach. Ahmed A. Moustafa, editor. Computational Models of Brain and Behavior (pp. 57-71). John Wiley & Sons 2017年11月 (ISBN: 9781119159063). fulltext