카본 투석액 재생시스템
카본 투석액 재생시스템
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Schematic diagrams of HD with the CDRS (a) and the mathematical models for a patient undergoing CHD (b) and HD with the CDRS (c). P = Fluid pump; – – – = solute transfer; –––––– = f luid trans- fer; ic = intracellular; is = interstitial; pl = plasma; ex = extracellular; b = blood; d = dialysate; s = mass transfer coefficient of solute s between the intracellular and ex- tracellular compartments; s = equilibri- um ratio of solute s; V = compartment vol- ume; Ms = mass of solute s; Js = removal rate of solute s across the dialyzer; Rv = flu- id reabsorption rate at the venous capillar- ies; Fa = fluid filtration rate at the arterial capillaries; kf = osmotic filtration coeffi- cient at the cellular membrane; Q = extra- corporeal flow rate; AR = adsorption ratio; in = inlet; out = outlet. Modified from our previous study, Ursino et al., and Depner and Garred
Schematic diagram of the in vitro experiment. S = Sam- pling point; P = fluid pump; AC = activated carbon
Characteristic curves of the UAR obtained by polynomial fitting of measured data according to dialysate flow rates of 100 (+), 200 (I), 300 (d), and 400 (f) ml/min
Time-varying concentration of urea in the intracellular (Uic), plasma (Upl), and dialysate (Ud) compartments (simulation result vs. experimental result) at a blood flow rate of 96 ml/min and dialysate flow rate of 247 ml/min. ex = Experimental data
Kt/V indices after 4 h of simulated CHD (grey) and HD with the CDRS (hatched) according to the dialysate flow rate. The blood flow rate is fixed at 300 ml/min
Comparisons of EKRc (a) and std Kt/V (b) among daily CHD (y), thrice-weekly CHD (_), daily HD with CDRS (I), and thrice-weekly HD with CDRS (+)
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