• Researcher

• E-mail : krrhj0707@gmail.com

• IT융합공학과 (Dept. of IT Convergence Engineering)

• 박사과정 (Ph.D Candidate)

• Research field: Development of a wearable BP estimation device

• E-mail : ariks131@gmail.com

Research progress: 

1. "in silico Cardiac Safety Assessment Using a Multi-Biomarker Approach Based on an Electrophysiological Model of hiPSC-Derived Cardiomyocytes" - Submitted to Toxicological Research Journal (Current status: Revision)

2. Developing Biopulse - a device for real-time measurement of bio signals for educational biomedical experiments and human physiological digital twins - Testing the EEG function for SSVEP and SSAEP 

• IT융복합공학과 (Dept. of IT Convergence Engineering)

• 박사과정 (Ph.D Candidate)

• Research Field: Software Engineering and in silico experimentation and simulation

• E-mail : aroli.marcellinus@gmail.com

Research progress: 

Progress-12th March 2026

• IT융합공학과 (Dept. of IT Convergence Engineering)

• 박사과정 (Ph.D Candidate)

• Research field: Bio-Simulation and drug screening for cardiac toxicity assessment

• E-mail : nurulqashrimt@gmail.com

Research progress (12/03/2025)

1. In Silico Evaluation of Cardiac Electrophysiological Effects of Mitoxantrone and Ribavirin using the ORd ventricular cell model

• Under review -  In silico Pharmacology Journal

2. Phenotype Specific in silico Prediction of Drug-Induced Proarrhythmia Across Sex and Heart-Failure Condition" - 

   • Under review -  Toxicological Research Journal

  3. In Silico Safety Assessment of Drug-Induced Atrial Arrhythmias Based on Atrial Electrophysiology Models

• Technical chekcs- Cardiovascular Drugs and Therapy Journal

  4. Evaluating Neoadjuvant Therapy Response: A Retrospective Study on the ACRIN 6698 Cohort

• Paper review

• Model duplication and preliminary testing

• Fractal dimension extraction

  5. In silico Evaluation of Cardiac Electrophysiological Effects of Mitoxantrone and Ribavirin Using  3D ToR - ORd in silico Model

• Pending

• IT융합공학과 (Dept. of IT Convergence Engineering)

• 박사과정 (Ph.D Candidate)

• Research Field: In silico experimentation and simulation

• E-mail : ariyadi@lecturer.itk.ac.id

• IT융합공학과 (Dept. of IT Convergence Engineering)

• 박사과정 (Ph.D Candidate)

• Research field: Bio-Simulation and drug screening for cardiac toxicity assessment

• E-mail : muhadnanpramudito@gmail.com

Research progress: 

1. "Validation of in silico Cardiac Safety Assessment Using Trend Similarity and Pearson Correlation with hiPSC-Derived in vitro Data" - Submitted to Annals of Biomedical Engineering (Rejected) -> Biomedical Engineering Letters (Current Status: Still in Manuscript Revision)

2. "A Novel in silico Cardiac Safety Assessment Using Action Potential Shape–Derived Torsadogenic Safety Margins" - Submitted to IEEE journal of Biomedical and Health Informatics (Pharmaceutical Research Journal (Rejected) -> IEEE journal of Biomedical and Health Informatics (Need minor revision))

3. Lab-Specific Validation using Torsadogenic Safety Margins - Still in Manuscript Preparation

4. MEA-DADA: MEA-based Deep Adversarial Domain Adaptation for TdP Risk Prediction - Fixing the Domain Discrimination Algorithm Code in MEA-DADA. 

5. "in silico Validation and Quantitative Evaluation of One-Dimensional Cardiac Tissue Model Using MEA-Based Experimental Comparison using Trend Similarity and Correlation Score for Cardiac Safety" (in collaboration with Byeong Gyu) - Byung Gyu Research

6. "Greedy Classifier-Based Identification of Proarrhythmic Biomarkers from One-Dimensional Cardiac Tissue Simulation" - Not Yet

7. “Tissue Digital Twin in collaboration with NEXEL” - Still in the Literature Study

8. Meta Heart Catalog Book - Revising the previous version (Current Status: Done) (link)

9. Broshure:

   1. CardioSim: DONE

   2. ToxCML: DONE

   3. BioPulse: Working in progress for the New Version (link)

10. Video Advertisement:

    1. CardioSim: Concept Preparation (link)

    2. BioPulse: DONE (need to update the BioPulse Design)

11. BioPulse Tutorial Video:

    1. Single Lead ECG: Still in Editing process for the New Version (link)

    2. PCG: Waiting Screen Record

    3. PPG: Waiting Screen Record

    4. EMG & Myometer: Waiting Screen Record

    5. Spirometer: Waiting Screen Record

    6. Body Temperature: Not Yet

    7. EOG: Not Yet

    8. V-PPG: Not Yet

    9. FeO2: Not Yet

    10. PPG / SpO2: Not Yet

    11. 16 Ch. EEG: Not Yet

    12. NIBP: Not Yet

    13. Stethoscope: Not Yet

    14. 12 Lead ECG: Not Yet

12. Next Plan

• IT융합공학과 (Dept. of IT Convergence Engineering)

• 박사과정 (Ph.D Candidate)

• Research field: Bio-Simulation and drug screening for cardiac toxicity assessment

• E-mail : hanumulfalatifa@gmail.com

Research progress : 

1. "Multi-Biomarker Based in silico Prediction of Drug-Induced Cardiac Proarrhythmic Risk Using the ToR-ORd Ventricular Model"

• Toxicology Letters (Under Review) - 2026/02/07

2. "Improving Biomarker Robustness for in silico Cardiac Safety Assessment through an Excitation-Contraction Coupling Model"

• Computer Methods and Programs in Biomedicine (Submitted to Journal) - 2026/02/27

3. "Electrophysiological Validation of ORdStatic and ToR-ORd Models With and Without Land Electromechanical Coupling to Inform CiPA-Aligned Model Selection"

• Manuscript Preparation (Abstract and Figure editing stage) *plan to finish all and send it to the professor: 2026/03/18

4. "Lab-Specific Validation of a CiPA-Based Multibiomarker Framework for Proarrhythmic Risk Assessment Using the ToR-ORd+Land Model"  

• Manuscript Preparation
  Figure and Table: 50%
  Introduction: 30%
  Methods: not yet
  Results: not yet
  Discussion: not yet
  Conclusion and Abstract: not yet

5. "Multibiomarker Evaluation of the Next-Generation ToR-ORddynCL+Land Model for Drug-Induced Torsadogenic Risk Prediction"

• Manuscript Preparation
  Figure and Table: not yet
  Introduction: not yet
  Methods: not yet
  Results: not yet
  Discussion: not yet
  Conclusion and Abstract: not yet 

6. "Validation of the ToR-ORddynCL" - in queue for in silico simulation process

7. Run Chantest and Nanion dataset (in silico simulation process) = for lab-specific validation process
   a. ToR-ORd+Land = Chantest and Nanion dataset (Done)
   b. ToR-ORd = Chantest and Nanion dataset (in queue)

• IT융합공학과 (Dept. of IT Convergence Engineering)

• 석사과정 (PhD Candidate)

• Research field: cardiac bio-simulation 

• E-mail : lufirdaus@gmail.com

Research progress:

1. CNN-Based Arrhythmia Classification from 1D Monodomain Field Potentials for TSM Drug Risk Assessment (with Adnan)  - ongoing simulations

• IT융합공학과 (Dept. of IT Convergence Engineering)

• 석사과정 (Master Candidate)

• Research field: Cardiovascular Digital Twin

• E-mail : rahmafatin.izza@gmail.com

Research progress (updated on 12 March 2026): 

1. "Cardiovascular Digital Twin via Optimization of a Windkessel–Baroreflex Model Using Blood Pressure Data" - Submitted to Biomedical Engineering Letters (Revision Needed - 26 Feb)

• Revising manuscript based on reviewer's comment

• Done 20/22 revisions includes 7/8 major revision

• Next plan: reference cross check, and manuscript refinement

2. "Inverse BSP to HSP" - Postponed after 1st topic revision

• Last progress: Face error in traininig result, not showing the proper result

3. "Cardiovascular-Renal-Hormone Digital Twin"  - Pending

4. "0D-1D Cardiovascular System" - Pending

• 의료 IT 융합 공학과 (Dept. of Biomedical Engineering)

• 석사과정 (Master Candidate)

• Research field: Bio-Simulation and drug screening for cardiac toxicity assessment

• E-mail :  yosiolvia10@gmail.com

Research progress :

1. "Incorporating Inter-Individual Variability to Improve the Reliability of Predicted Outcomes in in silico Cardiac Safety Assessment"

 - Submitted to Toxicology and Applied Pharmacology (Under Review) - 2026/03/04

2. "Multi-Biomarker Based in silico Drug Cardiac Safety Evaluation Strategy Accounting for Inter-Individual Variability"    

 -  writing the manuscript, Plan to submit to Toxicological Sciences journal  

3. "Lab Implementation  Using Inter-individual Data" -  On-going simulation using chantest and nanion dataset 

4. "Cardiac Risk Prediction of TdP Risk One Dimensional Cardiac Tissue Simulation"  - Pending, waiting for the latest code updates 

5. "Purkinje fiber mesh" -  Completed for both ventricle  (simulation in queue with Ariyadi )

6. "New Ventricle mesh"- Done, Simulation with apex completed

7. "Preparing heterogeneous simulations in the new ventricular model" -  Done extracting endocardial and epicardial nodes (simulation in  queue with Ariyadi ) 

• 의공학과 (Dept. of Biomedical Engineering)

• 석사과정 (Master Candidate)

• Research field: Cuff-less holter blood pressure device

• E-mail : rht7565@gmail.com

Research progress:

1. Developing Biopulse - a device for real-time measurement of bio signals for educational biomedical experiments and human physiological digital twins - Developing design and Testing

2.  Manufacture of non-invasive blood pressure measuring equipment - Design and Synchronization 

• 의료 IT 융합 공학과 (Dept. Biomedical Engineering)

• 석사과정 (Master Candidate)

• Research field: Network pharmacology, molecular docking, QSAR chemoinformatics, and digital twin development. 

• E-mail : fauzanresearchermedit@gmail.com

Research progress (https://bit.ly/FauzanProgressReport): 

1. "Interpretable Multi-Modality Consensus QSAR Framework: Integrating Machine and Deep Learning for Enhanced Multi-Endpoint Toxicity Assessment" -  Toxicology Mechanisms and Methods (Accepted)

2. "ToxCML: A Hybrid mfCoQ-RASAR-Based Platform Integrating Consensus QSAR and Read-Across for Comprehensive Multi-Endpoint Toxicity Assessment" - Journal of Chemical Information and Modelling (Major Revision)

3. "Unveiling the Therapeutic Potential of L-Serine Against Autism Spectrum Disorder: Insights from Network Pharmacology and Molecular Docking " - preparing the manuscript

4. "Adaptive MRI-Guided Digital Twin for Personalized Simulation of Breast Tumor Progression and Therapeutic Response" - development of the mathematical model and code implementation

5. Cardiosim-Tox: An Interpretable Multi-Task Deep Learning QSAR Integrating Multi-Modal Molecular Representations for hERG, Cav1.2, and Nav1.5 Blockade Risk and Potency Prediction - Model Development (Traning and Evaluation)

• 의료 IT 융합 공학과 (Dept. of Medical IT Convergence Engineering)

• 석사과정 (Master Candidate)

• Research field: Molecular Docking and Dynamic Simulation

• E-mail : afrinsanjida246@gmail.com

 Research Progress: 

1. "Working on PBPK Modeling Software & Simulation Tools."

• 의료 IT 융합 공학과 (Dept. of Biomedical Engineering)

• 석사과정 (Master Candidate)

• Research field : Network Pharmacology and Molecular Docking  Simulation

• E-mail : putri.nadillahafani@gmail.com

Research Progress:

1. Korean Language Program by KGKS

• 의공학과 (Dept. of Biomedical Engineering)

• 석사과정 (Master Candidate)

• Research field: Drug Screening for Cardiac Toxicity Assessment

• E-mail : littleprk59@gmail.com

Research progress:

1. "in silico Validation and Quantitative Evaluation of Cardiac Tissue Model Using MEA-Based Experimental Comparison using Trend Similarity and Correlation Score for Cardiac Safety" (in collaboration with Adnan) - Expanding research to Tomek model. 1D and 2D.

• 의공학과 (Dept. of Biomedical Engineering)

• 석사과정 (Master Candidate)

• Research field: Software and GUI Implementation 

• E-mail : uzanlatif@gmail.com

Research progress:

1. "BIOPULSE software implementation" - EEG heatmap GUI

2. "CardioSim software implementation" - Waiting for other module to implement