AGILENT INFINITY 1290 II / LC-MS / MS is extensively applied for the trace analysis of organic substances of pharmaco-toxicological interest in complex matrices (environmental and agri-food matrices, pharmaceutical and nutraceutical products, fluids and biological tissues). In areas of biomedical interest, LC-MS / MS can be used for the determination in biological fluids of steroid and peptide hormones and / or substances capable of altering their levels (e.g. endocrine disruptors), for therapeutic monitoring, for study of the metabolism of new active ingredients, for the analysis of new drugs of abuse in biological and non-biological matrices.

CytoFLEX S flow cytometry system (Beckman Coulter), equipped with four lasers and the capacity for 15 parameters, including 13 for fluorescence detection. Kaluza 2.0 (Beckman-Coulter) and FlowJo X (Treestar) softwares for analyses.

QX200 Droplet Digital PCR (ddPCR) System (Bio-Rad Laboratories),  providing absolute quantification of target DNA or RNA molecules, equipped with QuantaSoft Software (Bio-Rad Laboratories) for miRNA expression analyses.

Model: Bio-Rad CFX Connect Real-Time System

The CFX Connect Real-Time System allows for dual target analysis and has excellent thermal cycling characteristics. The system incorporates innovative optical technologies with powerful software in order to provide high reliability and efficiency.

The isolated heart or Langendorff heart is an in vitro technique used in pharmacology and physiology that allows to examine contractility and heart rate without the problems of in vivo methods.

The "ChemiDoc MP" is a very flexible imaging system, capable of detecting colorimetric, chemiluminescent, fluorescent, red, green, blue and UV signals. It is also compatible with the 48 “Stain Free” technology for the visualization of proteins, immediately after the electrophoretic run.

Model: Nikon Eclipse Ti

The inverted  microscope is equipped with systems for acquisition or live cell imaging [Phase Contrast, fluorescence and Förster resonance energy transfer (FRET)]. It is also equipped with a Micro-incubator for temperature and CO2 environment control

Model: Crest Csrv II Lx

The confocal microscope is an optical microscope that is based on a technology aimed at significantly increasing the spatial resolution of the sample, eliminating the halos due to the light diffused by the out-of-focus planes of the specimen.

Model: Leitz Fluoenert TS

The optical microscope is a type of microscope that uses light with a wavelength from near infrared to ultraviolet, covering the entire visible spectrum.

The stereoscopic microscope, also known as a stereomicroscope, is a type of optical microscope designed to produce a stereoscopic view of an object. The stereoscopic microscope is often used to study the surfaces of a solid sample or to perform tasks such as dissection and microsurgery.

Model: Thermo Scientific Forma Steri-Cycle Cell

Cell incubators are used for both primary cultures (eg cardiomyocytes) and cell lines (eg HL1, BT3). The device allows you to set the temperature and the percentage of CO2.

Model: Eppendorf Centrifuge 5424 R

5424 R centrifuges set new laboratory standards. With a capacity of 24 – places and a maximum speed of 21,130 x g they are perfectly equipped for all modern molecular biology applications in Eppendorf tubes and PCR

Model: BIOER XP Cycler

The thermocycler is a laboratory instrument capable of automatically conducting the certain cyclic temperature changes necessary for the enzymatic amplification of DNA sequences in vitro through the polymerase chain reaction (PCR).

The GloMax®-96 Microplate Luminometer is a state-of-the-art microplate luminometer that meets the requirements of high sensitivity and wide application range. It is required for chemiluminescent and bioluminescent applications.

These particular hoods are dedicated to primary cell cultures.