Drosophila melanogaster has long been a premier genetic model for biomedical research, providing crucial insights into genetics, development, and disease. However, maintaining live fly stocks requires continuous care, making it labor-intensive, costly, and vulnerable to risks such as genetic drift and accidental strain loss.
We are working to provide a robust and accessible cryopreservation method for Drosophila melanogaster that preserves valuable genetic resources, prevents strain loss, and reduces long-term maintenance costs. By making this technology widely available, we aim to enhance the efficiency and sustainability of Drosophila research across laboratories worldwide.
By analyzing embryo survival, hatching rates, and subsequent development into fertile adults, we identify optimal storage parameters that maximize recovery rates while maintaining genetic integrity. Additionally, we examine factors such as ice recrystallization, cryoprotectant stability, and strain-specific responses to long-term freezing. Through these studies, we aim to refine best practices for Drosophila cryopreservation, ensuring that stored strains remain viable and genetically stable over extended periods.
We will continue to optimize cryopreservation protocols to ensure consistent and high survival rates across diverse Drosophila melanogaster strains. We strive to develop adaptable methods that preserve genetic integrity, minimize variability, and make cryopreservation a universally reliable tool for the research community.