Research Endeavors

We are proud to have a productive and busy pediatric rehabilitation medicine department.

Ongoing studies include:

1. I-ACQUIRE trial: Constraint therapy for infants with perinatal ischemic stroke.

2. Adaptive sports in children and adolescents with myelomeningocele

3. Rehabilitation outcomes after COVID-19

4. Martial Arts Training in Children with Down Syndrome

5. Peripheral neuropathy monitoring in oncology patients

6. SMA outcome measurement

7. Wellness and health outcomes in adults with CP

National Research Opportunities: We are part of the Cerebral Palsy Research Network and Cure SMA.

• https://cprn.org/

• https://www.curesma.org/

Recent Publications 2022—2025:

Pruente J, Hurvitz E, Ayyangar R: Cerebral Palsy. In Young M Physical Medicine & Rehabilitation Secrets,4th, Hanley and Belfus Inc, (2022)

Daunter AK, Bowman A, Danko J, Claflin ES, Kratz AL: Functional decline in hospitalized patients with COVID-19 in the early months of the pandemic. PM R.14(2): 198-201, 02/2022. PM33929087

Sugiyama T, Whitney DG, Schmidt M, Haapala H, Bowman A, Peterson MD, Hurvitz EA: Measuring grip strength in adolescents and adults with cerebral palsy in a clinic setting: Feasibility, reliability, and clinical associations. Dev Med Child Neurol.66(1): 87-94, 01/2024. PM37277918

Nichols L, Bowman A, Gelehrter S, Green G, Olive M, Patel-Peters N, Ramsey AM, Reed L, Stepanovich M, Saba T: Trisomy 18: Clinical Practice Guideline, 03/2023

Mousigian MA, Rosenblum SA, Neil Knierbein EE, Daunter AK: Neonatal baclofen withdrawal

following intrauterine exposure. J Pediatr Rehabil Med.15(2): 389-394, 01/2022. PM35094999

Daunter AK, Pruente J, Bowman A, Whitney DG: Identifying racial disparities in care for children with spastic cerebral palsy: A single center study. J Pediatr Rehabil Med.16(1): 219-222, 01/2023. PM36314227

Pruente J, Daunter AK, Bowman A, Erickson SR, Whibley D, Whitney DG: Trajectories of medication use and polypharmacy among children with cerebral palsy. J Manag Care Spec Pharm.29(1): 58-68, 01/2023. PM36580123

Whitney DG, Neil Knierbein EE, Daunter A: Prevalence of morbidities across the lifespan for adults with spinal muscular atrophy: A retrospective cohort study. Orphanet Journal of Rare Diseases.08/2023. PM37653507

Groh WJ, Bhakta D, Tomaselli GF, Aleong RG, Teixeira RA, Amato A, Asirvatham SJ, Cha Y-M, Corrado D, Duboc D, Goldberger ZD, Horie M, Hornyak JE, Jefferies JL, Kääb S, Kalman JM, Kertesz NJ, Lakdawala NK, Lambiase PD, Lubitz SA, McMillan HJ, McNally EM, Milone M, Namboodiri N, Nazarian S, Patton KK, Russo V, Sacher F, Santangeli P, Shen W-K, Sobral Filho DC, Stambler BS, Stöllberger C, Wahbi K, Wehrens XH T, Weiner MM, Wheeler MT, Zeppenfeld K: 2022 HRS expert consensus statement on evaluation and management of arrhythmic risk in neuromuscular disorders. Heart Rhythm.19(10): e61-e120, 10/2022. PM35500790

Whitney DG, Caird MS, Jepsen KJ, Hurvitz EA, Hirth RA: Excess healthcare spending associated

with fractures among adults with cerebral palsy. Disability and Health Journal.02/2022. PM35370108

Whitney DG, Caird MS, Clines GA, Hurvitz EA, Jepsen KJ: Clinical bone health among adults with cerebral palsy: moving beyond assessing bone mineral density alone. Developmental Medicine & Child Neurology.64(4): 469-475, 04/2022. PM34658010

McPhee PG, Benner JL, Sanvido L, Roebroeck ME, van den Berg-Emons RJ, van der Slot WM,

Verschuren O, Hurvitz EA, Peterson MD, Gorter JW: A core outcome set for multimorbidity risk in individuals with cerebral palsy. Developmental medicine and child neurology.7: 881-889, 07/2022. PM35174883

Peterson MD, Kamdar N, Haapala HJ, Brummett C, Hurvitz EA: Opioid prescription patterns among adults with cerebral palsy and spina bifida. Heliyon.8(7): e09918, 07/2022. PM35847615

Whitney DG, Wolgat EM, Ellenberg E, Hurvitz EA, Schmidt M: The paradoxical relationship between severity of cerebral palsy and renal function in middle-aged adults: Better renal function or inappropriate clinical assessment?. Disability and Rehabilitation.44(15): 3853-3859, 08/2022. PM33635734

Peterson M, Wilson A**, Hurvitz E: Underlying Causes of Death among Adults with Cerebral Palsy. 10/2022. PM36362560

Sarmiento CA, Gannotti ME, Gross PH, Thorpe DE, Hurvitz EA, Noritz GH, Horn SD, Msall ME,

Chambers HG, Krach LE: Adults with cerebral palsy and chronic pain experience: A cross-sectional analysis of patient-reported outcomes from a novel North American registry. Disabil Health J.: 101546, 11/2023. PM37993325

Leis AM, Hurvitz EA, Whitney DG: Comorbidity Clusters Among Adults With Cerebral Palsy: A Latent Class Analysis. Am J Prev Med.01/2024. PM38278372

Whitney DG, Rabideau M, McKee M, Hurvitz EH: Preventive care for adults with cerebral palsy and other neurodevelopmental disabilities: Are we missing the point?. Frontiers in Integrative

Neuroscience.1603/2022. PM35464602

Whitney DG, Schmidt M, Hurvitz EA: Corrigendum: Shared Physiologic Pathways Among

Comorbidities for Adults With Cerebral Palsy. Frontiers in neurology.1201/2022. PM35115999

Whitney DG, Rabideau ML, McKee M, Hurvitz EA: Preventive Care for Adults With Cerebral Palsy and Other Neurodevelopmental Disabilities: Are We Missing the Point?. Frontiers in Integrative Neuroscience.16 (866765) 04/2022

Hearn SL, Hurvitz EA, Eckner JT, Mallow MK, Spires MC: Academic Discourse With Trainees: A Guide for Departments. Am J Phys Med Rehabil.102(5): e74-e75, 05/2023. PM36762845

Whitney DG, Caird MS, Jepsen KJ, Hurvitz EA, Hirth RA: Excess healthcare spending associated with fractures among adults with cerebral palsy. Disabil Health.In Press03/2022

Whitney DG, Caird MS, Clines GA, Hurvitz EA, Jepsen KJ: Clinical bone health among adults with cerebral palsy: moving beyond assessing bone mineral density alone. Developmental medicine and child neurology.4: 469-475, 04/2022

Peterson MD, Kamdar N, Haapala HJ, Brummett C, Hurvitz EA: Opioid prescription patterns among adults with cerebral palsy and spina bifida. Heliyon.707/2022

Kahn RE, Krater T, Larson JE, Encarnacion M, Karakostas T, Patel NM, Swaroop VT, Dayanidhi S. Resident muscle stem cell myogenic characteristics in postnatal muscle growth in children with cerebral palsy. American Journal of Physiology-Cell Physiology. 2023, PubMed 36622072.

LoPresti MA, Horak VJ, Trierweiler R, Stone LE, Krater T, Raskin JS. Navigated Radiofrequency Ablation Peripheral Rhizotomy for Lumbosacral Hypertonia in a Nonambulatory Patient With Spinal Fusion: Indications, Surgical Techniques, and Lessons Learned. Oper Neurosurg (Hagerstown). 2023 Sep 4;25(5):461–8. doi: 10.1227/ons.0000000000000860. Epub ahead of print. PMID: 37668987; PMCID: PMC10561801.

Pruente J, Heinemann AW, Zebracki K, Mukherjee S, Gaebler-Spira D: Adult outcomes for children who sustained firearm-related spinal cord injuries. J Spinal Cord Med.46(1): 68-74, 01/2023. PM34232844

Ayoubi L, Pruente J, Daunter A, Erickson S, Whibley D, Whitney D: Opioid prescription patterns among commercially insured children with and without cerebral palsy. Journal of Pediatric Rehabilitation Medicine.17(1): 47-56, 03/2024. PM38489199

Verduzco-Gutierrez M*, Raghavan P, Pruente J, Moon D, List C, Hornyak J, Gul F, Deshpande S, Biffl S, Lawati Z, Alfaro A: AAPM&R consensus guidance on spasticity assessment and management. PM&R.: 1-24, 05/2024. PM38770827

Whitney, D. G., Oliverio, A. L., Kreschmer, J., Bolde, S., Hurvitz, E. A., & Wong, K. K. (2024). Feasibility and reliability of measured glomerular filtration rate with [I125]-iothalamate among young adults with mild-to-moderate cerebral palsy. Frontiers in Medicine, 11, 1295104. https://doi.org/10.3389/fmed.2024.1295104

Mossner, J., Abdelmageed, S., Votoupal, M., Misasi, J., Saleh, N., Dziugan, K., Krater, T., & Raskin, J. S. (2024). Safety and efficacy of continuous intrathecal baclofen via cervical catheter tip: A retrospective case series. Neurosurgical Focus, 56(6), E13. https://doi.org/10.3171/2024.4.FOCUS24147

Abdelmageed, S., Dalmage, M., Mossner, J. M., Trierweiler, R., Krater, T., & Raskin, J. S. (2024). Nonselective lumbosacral ventral-dorsal rhizotomy for the management of lower-limb hypertonia in nonambulatory children with cerebral palsy. Neurosurgical Focus, 56(6), E9. https://doi.org/10.3171/2024.4.FOCUS24101

Gannotti, M. E., Sarmiento, C. A., Gross, P. H., Thorpe, D. E., Hurvitz, E. A., Noritz, G. H., Horn, S. D., Msall, M. E., Chambers, H. G., & Krach, L. E. (2024). Adults with cerebral palsy and functional decline: A cross-sectional analysis of patient-reported outcomes from a novel North American registry. Disability and Health Journal, 17(3), 101593. https://doi.org/10.1016/j.dhjo.2024.101593

Gannotti, M. E., Gross, P. H., Thorpe, D. E., Hurvitz, E. A., Noritz, G. H., Horn, S. D., Msall, M. E., Chambers, H. G., Krach, L. E., & Sarmiento, C. A. (2024). Cerebral palsy research network community registry adult surveys on function & pain: Successes, challenges, and future directions. Disability and Health Journal, 17(3), 101625. https://doi.org/10.1016/j.dhjo.2024.101625

Peterson, M. D., Ashbaugh, K., O’Leary, M., Schmidt, M., Haapala, H., Kamdar, N., & Hurvitz, E. A. (2024). Pain phenotypes and pain multimorbidity among Medicare beneficiaries with cerebral palsy. JAMA Neurology, 81(9), 1004–1005. https://doi.org/10.1001/jamaneurol.2024.2443

Hurvitz, E., Wyeth, D., & Peterson, M. (2024). Transitioning health care for adults with cerebral palsy. Developmental Medicine & Child Neurology, 67(2), 146–147. https://doi.org/10.1111/dmcn.16055

Abdelmageed, S., Villalba, N., Mossner, J., Krater, T., & Raskin, J. S. (2024). Heterotopic osteotomy for intrathecal baclofen test dose administration in a pediatric patient with spinal fusion: A technical note. Operative Neurosurgery, 29(1), 131–134. https://doi.org/10.1227/ons.0000000000000865

Whitney, D. G., Min, L. C., & Hurvitz, E. A. (2024). Age, sex, and multi-morbidity stratified mortality risk estimates for adults with cerebral palsy to inform clinical decision making. Disability and Health Journal, 18(1), 101683. https://doi.org/10.1016/j.dhjo.2024.101683

Whitney, D. G., & Hurvitz, E. A. (2025). Prediction models for risk of cardiorespiratory morbidity/mortality and fracture among young adults with cerebral palsy. Journal of Cachexia, Sarcopenia and Muscle, 16(2), e13640. https://doi.org/10.1002/jcsm.13640

Peterson, M. D., O’Leary, M., Ashbaugh, K., Haapala, H., Schmidt, M., Kamdar, N., & Hurvitz, E. A. (2025). Medication and therapy profiles for pain and symptom management among adults with cerebral palsy. Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 9(2), 100597. https://doi.org/10.1016/j.mayocpiqo.2025.100597

Sarmiento, C. A., Gannotti, M., Cohen, J., & Hurvitz, E. (2025). Priority setting for multicenter research among adults with cerebral palsy: A qualitative study. Disability and Rehabilitation, 1–12. https://doi.org/10.1080/09638288.2025.2459893

Sarmiento, C. A., Hurvitz, E., Cohen, J., & Gannotti, M. (2025). Stakeholder perspectives on an adult cerebral palsy community registry: A qualitative study. Disability and Health Journal, 18(3), 101822. https://doi.org/10.1016/j.dhjo.2025.101822

Jha, S. A., Bolde, S. M., Hurvitz, E. A., Caird, M. S., & Whitney, D. G. (2025). Fracture characteristics among adults with intellectual disabilities and autism spectrum disorders to inform fracture prevention strategies: A descriptive study. Journal of Intellectual Disability Research. Advance online publication. https://doi.org/10.1111/jir.13255

Vernacchia, C., Chu, Y., De Jesus, A., Couri, J., Sen, S., Gohil, K., De Marco, K., Darcy, R., Krater, T., Pavone, L., & Jayabalan, P. (2025). The impact of the COVID-19 pandemic on physical, social and emotional well-being in a cohort of children with disabilities in the United States. Journal of Paediatrics and Child Health, 61(7), 1102–1115. https://doi.org/10.1111/jpc.70082