Dr. Michele is a Professor of Physiology and Professor of Internal Medicine. Dr. Michele’s laboratory is interested in the molecular mechanisms of inherited muscle diseases, particularly muscular dystrophies and inherited cardiomyopathies. He is an expert and has strong personal interest in studying muscle and cardiac physiology and pathophysiology using gene targeting in mice to model human genetic muscle and cardiac diseases including muscular dystrophies. Dr. Michele also serves as Director of the Physiology Phenotyping Core (PPC).In his role as director of this core, Dr. Michele has recently been awarded an NIH funded K26 award to mentor post-doctoral fellows and graduate students and train them in state of the art mouse cardiovascular and exercise phenotyping platforms in our core facilities. Dr. Michele has supervised two post-doctoral fellows and five graduate students for their thesis work (2 currently), along with more than 20 undergraduate students in various fellowship and work study positions. As evidence for his dedication to training the next generation of scientists, Dr. Michele founded and serves as Director of the Frankel Cardiovascular Center’s Summer Undergraduate Fellowship Program which has just completed its 5th year and has grown to now offer 16 fellowship slots each summer. Dr. Michele serves as a faculty mentor for an underrepresented minority undergraduate fellowship program (NIH R25-HL108842), and has mentored 6 undergraduate minority students in his laboratory in various fellowship programs, as well as 3 underrepresented minority graduate students for rotations in his laboratory. In addition, Dr. Michele has been awarded several U.S. and international patents for technology that is currently licensed to Phrixus Pharmaceuticals in Ann Arbor for developing therapeutic application of tri-block co-polymers for treatment of muscular dystrophies and cardiomyopathies. As the Program Director, Dr. Michele will oversee all operations of the training program and coordinate the trainee selection process.
Dr. Jalife is Professor Emeritus of Internal Medicine and Molecular and Integrative Physiology. He served as the Director of the Cardiovascular Research Center and as Co-Director of the Center for Arrhythmia Research at the University of Michigan. Dr. Jalife enjoys an international reputation as a leader in the study of cardiac arrhythmias. His work has increased the understanding of the fundamental mechanisms of atrial fibrillation, ventricular tachycardia/fibrillation and sudden cardiac death. Dr. Jalife has served the National Institutes of Health in many capacities, including past membership in Research Committee-A, the Cardiology Advisory Committee, the Cardiovascular Study Section, (CVA), and the ESTA Study Section of the National Heart Lung and Blood Institute. He has also been a member of multiple site visit committees and Special Emphasis Panels of the NHLBI and research review committees of the American Heart Association. Between 2010 and 2012 he served as President of the Cardiac Electrophysiology Society. As there is currently no major administrative role for his Scholar position, Dr. Jalife focuses on both creative research endeavors as well as trainees. His joint appointments in clinical (Internal Medicine) and basic science (Molecular and Integrative Physiology) departments provide for a high level of exposure to highly qualified pre-doctoral (as well as postdoctoral) candidates. Dr. Jalife serves as a mentor in several T32 training programs here at the UM and throughout his career has trained more than 100 individuals, including underrepresented minorities, for research careers at nearly all educational levels (pre-doctoral fellow for PhD degrees, medical student, post-doctoral trainees, medical residents and clinical fellows). During the last five years, Dr. Jalife’s time at Michigan has been associated with the training of four PhD doctoral students, six post-doctoral students, several junior faculty, and several undergraduate students. In addition, as a joint and active faculty member in the Department of Molecular & Integrative Physiology, he trained graduate students, served on thesis committees, and participated in all the major facets of this important basic science department. As the Associate Director, Dr. Jalife will assist Dr. Michele in administration of the training program including serving as a key liason with his scientific network in industry and tech startup.