Circulation Research paper published online

Post date: Jul 4, 2020 7:45:10 PM

Just Published Online on July 1 2020: A key evolutionarily conserved housekeeping translation factor, glutamyl-prolyl-tRNA synthetase (EPRS), promotes pro-fibrotic proline-rich proteins during cardiac fibrosis. These findings will lead to discovery of translation factors and their regulated pro-fibrotic proteins (e.g., SULF1) as novel therapeutic targets for treatment of cardiac fibrosis and heart disease.

https://www.ahajournals.org/doi/abs/10.1161/CIRCRESAHA.119.315999