Pablo Cabrero

My current research interest are finding novel roles of cytochrome P450 genes in stress sensing by epithelia, developing Drosophila models of kidney stone formation , CLC channels localization and function in Malpighian tubules and Tyramine signalling. Publications

1. Ion and solute transport by Prestin in Drosophila and Anopheles.

Hirata T, Czapar A, Brin L, Haritonova A, Bondeson DP, Linser P, Cabrero P, Thompson J, Dow JA, Romero MF.J Insect Physiol. 2012 Jan 30. PMID:22321763

2.Immune and stress response 'cross-talk' in the Drosophila Malpighian tubule.

Davies SA, Overend G, Sebastian S, Cundall M, Cabrero P, Dow JA, Terhzaz S.

J Insect Physiol. 2012 Jan 28. PMID:22306292

3.Identification of human Neuromedin U as an orthologue of insect capa peptides and the role of capa receptor in organismal responses to water stress.

Terhzaz S, Cabrero P, Robben JH, Radford JC, Hudson BD, Milligan G, Dow JA, Davies SA.

PLoS One. 2012;7(1):e29897. Epub 2012 Jan 11. PMID:22253819

4.The receptor guanylate cyclase Gyc76C and a peptide ligand, NPLP1-VQQ, modulate the innate immune IMD pathway in response to salt stress.

Overend G, Cabrero P, Guo AX, Sebastian S, Cundall M, Armstrong H, Mertens I, Schoofs L, Dow JA, Davies SA.

Peptides. 2011 Aug 27. PMID:21893139

5.Mislocalization of mitochondria and compromised renal function and oxidative stress resistance in Drosophila SesB mutants.

Terhzaz S, Cabrero P, Chintapalli VR, Davies SA, Dow JA.

Physiol Genomics. 2010 Mar 3;41(1):33-41. PMID:20009008

6.Changes of intra-mitochondrial Ca2+ in adult ventricular cardiomyocytes examined using a novel fluorescent Ca2+ indicator targeted to mitochondria.

Kettlewell S, Cabrero P, Nicklin SA, Dow JA, Davies S, Smith GL.

J Mol Cell Cardiol. 2009 Jun;46(6):891-901. PMID:19249308

7.Salty dog, an SLC5 symporter, modulates Drosophila response to salt stress.

Stergiopoulos K, Cabrero P, Davies SA, Dow JA.

Physiol Genomics. 2009 Mar 3;37(1):1-11. PMID:19018044

8.A new role for a classical gene: white transports cyclic GMP.

Evans JM, Day JP, Cabrero P, Dow JA, Davies SA.

J Exp Biol. 2008 Mar;211(Pt 6):890-9. PMID:18310115

9.Novel subcellular locations and functions for secretory pathway Ca2+/Mn2+-ATPases.

Southall TD, Terhzaz S, Cabrero P, Chintapalli VR, Evans JM, Dow JA, Davies SA.

Physiol Genomics. 2006 Jun 16;26(1):35-45. PMID:16609144

10.Insect renal tubules constitute a cell-autonomous immune system that protects the organism against bacterial infection.

McGettigan J, McLennan RK, Broderick KE, Kean L, Allan AK, Cabrero P, Regulski MR, Pollock VP, Gould GW, Davies SA, Dow JA.

Insect Biochem Mol Biol. 2005 Jul;35(7):741-54. PMID:15894191

11.Functional characterisation of the Anopheles leucokinins and their cognate G-protein coupled receptor.

Radford JC, Terhzaz S, Cabrero P, Davies SA, Dow JA.

J Exp Biol. 2004 Dec;207(Pt 26):4573-86. PMID:15579553

12.Conservation of capa peptide-induced nitric oxide signalling in Diptera.

Pollock VP, McGettigan J, Cabrero P, Maudlin IM, Dow JA, Davies SA.

J Exp Biol. 2004 Nov;207(Pt 23):4135-45. PMID:15498959

13.A conserved domain of alkaline phosphatase expression in the Malpighian tubules of dipteran insects.

Cabrero P, Pollock VP, Davies SA, Dow JA.

J Exp Biol. 2004 Sep;207(Pt 19):3299-305. PMID:15326206

14.The Dh gene of Drosophila melanogaster encodes a diuretic peptide that acts through cyclic AMP.

Cabrero P, Radford JC, Broderick KE, Costes L, Veenstra JA, Spana EP, Davies SA, Dow JA.

J Exp Biol. 2002 Dec;205(Pt 24):3799-807. PMID:12432004