Lab Reagents, Clinical Tools, and Useful web links
Todd Lab in the news:
Profile of Peter Todd by the UM Center for RNA biomedicine (2020)
A lay discussion of native functions of CGG repeats in the Fragile X gene (2020)
A highlight of our work on ASOs as a method of blocking RAN translation (2020)
Article on our efforts to reactivate the Fragile X Gene (2018)
Press on cellular stress in C9orf72 RAN translation (2017)
Antibodies to FMRpolyG:
NTM1 or CTM1 antibodies, email petertod_at_med_dot_umich_edu.
7FM and 8FM Antibodies (from Sellier et al, Neuron, 2017): email ncharlet_at_igbmc.fr
2J7 antibody (from Todd et al, Neuron, 2013) is available commercially Here.
If issues with it, please contact us directly.
Other published antibodies: available upon request.
Clinical Tools for Ataxia and Movement disorders:
SARA Ataxia Rating scale: http://www.ataxia-study-group.net/html/about/ataxiascales/sara/SARA.pdf
MDS-UPDRS: http://www.movementdisorders.org/MDS-Files1/PDFs/MDS-UPDRS_English_FINAL.pdf
TETRAS Tremor rating scale: http://www.siumed.edu/neuro/pdfs/TETRAS%20v3_1.pdf
Ataxia Reviews:
Shakkottai and Fogel: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818725/pdf/nihms470336.pdf
Todd and Shakkottai, UpToDate: http://www.uptodate.com/contents/overview-of-cerebellar-ataxia-in-adults? source=search_result&search=Ataxia+adults&selectedTitle=1%7E150
Links to other relevant Departments, Centers, and Programs on Campus:
University of Michigan Department of Neurology: https://www.medicine.umich.edu/dept/neurology
Dr. Todd's clinic website: https://www.medicine.umich.edu/dept/neurology/peter-todd-md-phd
Center for RNA biomedicine: http://www.umichrna.org/
University of Michigan Neuroscience Graduate Department: http://neuroscience.med.umich.edu/
University of Michigan Cell and Molecular Biology Graduate Program: http://cmb.medicine.umich.edu/
VA medical Center Ann Arbor: http://www.annarbor.va.gov/
UM Sequencing Core: https://seqcore.brcf.med.umich.edu/