Advanced Biological Reaction Engineering

생물반응공학 특론

Date: 2017.9.1 updated

Instructor

Instructor Prof. Han Min Woo (우한민 교수님)

Teaching Assistant (TA) Mie Eun Yi (smsb.lab) (이미은 박사과정생)

Department Food Science and Biotechnology

Office location & hours 62-212, Thur. 5 pm - 6 pm or RSVP (Email: hmwoo@skku.edu)

Contact Information Tel: 031-290-7810, Email: Email: hmwoo@skku.edu

Course Objectives and Outlines

Objectives:

The objective of the course, as implied by the course content above, is to introduce advanced biological reaction engineering concepts primarily to biochemical engineers. The course does not assume any biological background or any prior courses in biology or microbiology, although it certainly helps to have some or much. To accommodate those who do not have the biological background, the course will first survey the basic ideas from microbiology, biochemistry, and bioprocess engineering. Subsequently, the emphasis will be application of the following core biological reaction engineering concepts to biological problems.

Overview of Microbiology

Biochemistry of Cells

Enzyme Technology

Molecular Biology and Metabolic Pathways

Microbial Growth Models

Bioreactor Analysis and Operation

Downstream Processing (product recovery and purification)

Genetic Engineering

Text and supplementary books

Text book:

1. Shuler, Michael L., and Fikret Kargi. Bioprocess Engineering: Basic Concepts. 2nd ed. Upper Saddle River, NJ: Prentice Hall PTR, 2001. ISBN: 9780130819086.

2. Biochemical Engineering Fundamentals Subsequent Edition by James E. Bailey (Author), David F. Ollis (Author)

3. Chemical Reaction Engineering, Octave Levenspiel (Author), John Wiley & Sons, Inc., ISBN:0-471-25424-X

Supplementary books: Various research papers.

Evaluation

Attendance 15%, Discussion 10%, Attitude 5%, Paper Project 20%, Mid Term 25%, Final 25%

(F grade: Below 13/16 attendance = <24.3 ==> (Total classes = 16 x 2 - 4 [interim] = 28 classes), 28 x 13/16 = 22.75)

Three days absent (= 6 classes missing) = 22: ==> F graded

Class dates

Class 01 03 Sep Introduction (shorten)

Class 02 10 Sep Introduction to biological reactions

Class 03 17 Sep Recent Biological reactions: Cell kinetics and Fermentor Design

Class 04 24 Sep Paper analysis and understanding - Metabolic engineering J.

Class 01 Oct No class -추석징검다리연휴

Class 05 08 Oct Paper analysis and understanding - Biotechnol. Bioeng. Proc.

Class 06 15 Oct No class - IUMS Online meeting

Class 07 22 Oct Paper analysis and understanding - mBio

Class 08 29 Nov No class - 공업화학회

Class 09 05 Nov Paper analysis and understanding - ACS Sustainable Chem. & Eng.

Class 10 12 Nov Paper analysis and understanding - Bioengineering & Biotechnology

Class 11 19 Nov Paper analysis and understanding - Molecular Biotechnology

Class 12 26 Nov Paper analysis and understanding - Bioresour. Technol.

Class 13 03 Dec Paper analysis and understanding - Biotechnology J.

Class 14 10 Dec Paper analysis and understanding - J. Biotechnol.

Class 15 17 Dec Final Exam.