Research

- Chemical Biology of bacterial virulence and biofilm formation                                                            

a) c-di-GMP signaling (biofilms)

b) Riboswitches as anti-virulence and anti-biofilm targets

c) Quorum sensing (virulence and Biofilms)

- New anticancer agents

a) Kinase inhibitors for cancer treatment

b) New ligands that bind to G-quadruplex DNA and i-motif

c) Cancer Immunotherapy with bacterial signaling molecules

d) Inhibitors of epigenetic machinery, such as demethylases

- Nucleic acid nanostructures and RNA/DNAzymes as next generation clinical diagnostics

a) Junction probe

b) G-quadruplex peroxidases and oxidases