Publications
→ At a glance:
Articles ranked by metrics:
Web of Science: 115 referenced articles, >5400 citations, H-index: 39
Scopus: 117 referenced articles, >5700 citations, H-index: 40
Google Scholar: 122 referenced articles, >7100 citations, H-index: 42
→ ORCID, PubMed & HAL (open access)
Articles and reviews ranked by journals' impact factor (with IF≤5, 5<IF<10, IF≥10, no IF):
Acc. Chem. Res. - ACS Catal. (x2) - ACS Chem. Biol. - Adv. Healthc. Mater. - Aging - Anal. Chem. - Angew. Chem. Int. Ed. (x5) - Autophagy - Biochim. Biophys. Acta - Biochimie (x3) - Bioorg. Med. Chem. Lett. - Carbon - CCS Chem. - Cell Chem. Biol. - Cells - Chinese J. Catal. - ChemBioChem (x3) - Chem. Commun. (x5) - Chem. Eur. J. (x6) - ChemMedChem. (x2) - Chem. Sci. - Chimia - Curr. Prot. Cell Biol. - eLife - Eur. J. Org. Chem. - Helv. Chim. Acta - Inorg. Chem. - Int. J. Biol. Macromol. - iScience - JACS Au - J. Am. Chem. Soc. (x9) - J. Biol Chem. - J. Biol. Inorg. Chem. - J. Chem. Theory Comput. - J. Med. Chem. - J. Mol. Biol. - J. Nucleic Acids (x2) - J. Org. Chem. (x2) - J. Organomet. Chem. - J. Pharm. Biomed. Anal. - Mol. Cell - Molecules - Nanoscale - Nat. Commun. (x2) - Nat. Protoc. - Nat. Rev. Chem. - Nat. Struct. Mol. Biol. - New J. Chem. - Nucleic Acids Res. (x8) - NAR Cancer - Organometallics - Org. Biomol. Chem. (x7) - Org. Lett. - Plant Phys. - Proc. Natl. Acad. Sci USA - RSC Chem. Biol. (x2) - Sci. Rep. (x2) - Synlett. - Tet. Lett. - Trends Genet.
Articles ranked by citations (source: google scholar):
Top cited articles (with ≥100 citations) : Bioorg. Med. Chem. Lett. 2006; J. Am. Chem. Soc. 2007, 2011, 2014 & 2015; Proc. Natl. Acad. Sci. USA 2007; ChemMedChem 2007; J. Biol. Inorg. Chem. 2007; Angew. Chem. Int. Ed. 2008, 2009, 2011 & 2017, Org. Biomol. Chem. 2007 & 2008, Biochimie 2008, Nat. Struct. Mol. Biol. 2011; Nucleic Acid Res. 2012; Inorg. Chem. 2014 ; Nat. Commun. 2018; Nat. Rev. Chem. 2019.
`→ In more detail:
Patents:
Biomimetic G-quartet compounds
David Monchaud, Ibai E. Valverde, Pauline Lejault and Francesco Rota Sperti
→ Licensed to Merck KGgA; commercial compounds (at Sigma Aldrich) can be found here (BioCyTASQ) and here (MultiTASQ)
Poly-heteroaryl derivatives for the treatment of cancer.
Chi-Hung Nguyen, Myriam Rouchon Dagois, Aurore Guédin-Beaurepaire, David Monchaud, Marie-Paule Teulade-Fichou, Jean-Francois Riou, Jean-Louis Mergny, David Grierson,
Published articles:
120 - PhpC modulates RNA G-quadruplex-RNA landscapes in human cells
Jérémie Mitteaux, Sandy Raevens, Zi Wang, Marc Pirrotta, Ibai E. Valverde, Robert H. E. Hudson and David Monchaud
Chem. Commun. 2024, accepted article
119 - UV-induced G4 DNA structures recruit ZRF1 which prevents UV-induced senescence
Alessio De Magis, Michaela Limmer, Venkat Mudiyam, David Monchaud, Stefan Juranek and Katrin Paeschke
118 - Pirh2-dependent DNA damage in neurons induced by the G-quadruplex ligand pyridostatin
Rocio Diaz Escarega, Abhijeet A. Patil, Jose F. Moruno-Manchon, Akihiko Urayama, Sean P. Marrelli, Nayun Kim, David Monchaud, Louise D. McCullough and Andrey S. Tsvetkov
J. Biol. Chem. 2023, 299, 105157
117 - The topology of DNA G-quadruplexes can be harnessed in Holliday junction-based DNA suprastructures to control and optimize their biocatalytic properties
Dehui Qiu, Mingpan Cheng, Petr Stadlbauer, Jielin Chen, Michal Langer, Xiaobo Zhang, Qiang Gao, Huangxian Ju, Jiří Šponer, Jean-Louis Mergny, David Monchaud and Jun Zhou
116 - Targeting DNA Junctions with Small Molecules for Therapeutic Applications in Oncology
Joanna Zell and David Monchaud
Handbook of Chemical Biology of Nucleic Acids (Ed. N Sugimoto), 2023, Chap. 32, pp 1051-1074
115 - BLM helicase protein negatively regulates stress granule formation through unwinding RNA G-quadruplex structures
Yehuda Danino, Lena Molitor, Tamar Rosenbaum-Cohen, Sebastian Kaiser, Yahel Cohen, Ziv Porat, Hagai Marmor-Kollet, Corine Katina, Alon Savidor, Ron Rotkopf, Eyal Ben-Isaac, Ofra Golani, Yishai Levin, David Monchaud, Ian D. Hickson and Eran Hornstein
Nucleic Acids Res. 2023, 51, 9369
114 - Development of a highly optimized procedure for the discovery of RNA G-quadruplexes by combining several strategies
Marc-Antoine Turcotte, François Bolduc, Anaïs Vannutelli, Jérémie Mitteaux, David Monchaud and Jean-Pierre Perreault
→ Special issue: Last Year in Marienbad (Ed. Jean-Louis Mergny)
113 - A versatile G-quadruplex (G4)-coated upconverted metal-organic framework for hypoxic tumor therapy
Xuanxiang Mao, Xiaobo Zhang, Zhicong Chao, Dehui Qiu, Shijiong Wei, Rengan Luo, Desheng Chen, Yue Zhang, Yun Chen, Yuanjiao Yang, David Monchaud, Huangxian Ju, Jean-Louis Mergny, Jianping Lei and Jun Zhou
Adv. Healthc. Mater. 2023, 2300561
112 - The multivalent G-quadruplex (G4)-ligands MultiTASQs allow for versatile click chemistry-based investigations
Francesco Rota Sperti, Jérémie Mitteaux, Joanna Zell, Angélique Pipier, Ibai E. Valverde and David Monchaud
111 - Chrysin-induced regression of angiogenesis via an induction of DNA damage response and oxidative stress in in vitro and in vivo models of melanoma
Aicha Sassi, Maxime Fredon, Alexia K. Cotte, Camille Fuselier, Christophe Schneider, Laurent Martiny, David Monchaud, Leila Chekir-Ghedira, Virginie Aires and Dominique Delmas
→ Special issue: Rejuvenating, geroprotective and cytoprotective activities of natural and synthetic compounds
110 - Side-by-side comparison of G-quadruplex (G4) capture efficiency of the antibody BG4 versus the small-molecule ligands TASQs
Yilong Feng, Zexue He, Zhenyu Luo, Francesco Rota Sperti, Ibai E. Valverde, Wenli Zhang and David Monchaud
109 - A chimeric biocatalyst combining peptidic and nucleic acid components overcomes the performance and limitations of the native horseradish peroxidase
Xiaobo Zhang, Dehui Qiu, Jielin Chen, Yue Zhang, Jiawei Wang, Desheng Chen, Yuan Liu, Mingpan Cheng, David Monchaud, Jean-Louis Mergny, Huangxian Ju and Jun Zhou
J. Am. Chem. Soc. 2023, 145, 4517
108 - Why does the pUG tail curl?
David Monchaud
Mol. Cell 2023, 83, 330 (Spotlight)
107 - Template-assembled synthetic G-quartets (TASQs): multiTASQing molecular tools for investigating DNA and RNA G-quadruplex biology
David Monchaud
106 - Interactions of small molecules with DNA junctions
Kane McQuaid, Angélique Pipier, Christine Cardin and David Monchaud
Nucleic Acids Res. 2022, 50, 12636
105 - rG4detector, a novel RNA G-quadruplex predictor, uncovers their impact on stress granule formation
Maor Turner, Yehuda M. Danino, Mira Barshai, Nancy S. Yacovzada, Yahel Cohen, Tsviya Olender, Ron Rotkopf, David Monchaud, Eran Hornstein and Yaron Orenstein
Nucleic Acids Res., 2022, 50, 11426
104 - Omics studies of G-/C-quadruplexes in plants
Mengqi Li, Ruiping Tian, David Monchaud and Wenli Zhang
103 - Click chemistry-based biomimetic ligands efficiently capture G-quadruplexes in vitro and help localize them at DNA damage sites in human cells
Francesco Rota Sperti, Baptsite Dupouy, Jérémie Mitteaux, Angélique Pipier, Marc Pirrotta, Nicolas Chéron, Ibai E. Valverde and David Monchaud
102 - An Efficient Biocatalytic System for Biosensing by Combining Metal-Organic Framework (MOF)-Based Nanozymes and G-quadruplex (G4)-DNAzymes
Xuanxiang Mao, Fangni He, Dehui Qiu, Shijiong Wei, Rengan Luo, Yun Chen, Xiaobo Zhang, Jianping Lei, David Monchaud, Jean-Louis Mergny, Huangxian Ju and Jun Zhou
101 - Targeting a G-quadruplex from let-7e pre-miRNA with small molecules and nucleolin
Tiago Santos, André Miranda, Lionel Imbert, David Monchaud, Gilmar F. Salgado, Eurico J. Cabrita and Carla Cruz
J. Pharm. Biomed. Anal. 2022, 215, 114757
100 - Global mapping of RNA G-quadruplexes (G4-RNAs) using G4RP-seq
Sunny Y. Yang, David Monchaud and Judy M. Y. Wong
99 - Genome-wide characterization of i-motifs and their potential roles in the stability and evolution of transposable elements in rice
Xing Ma, Yilong Feng, Ying Yang, Xin Li, Yining Shi, Shentong Tao, Xuejiao Cheng, Jian Huang, Xiu-e Wang, Caiyan Chen, David Monchaud and Wenli Zhang
Nucleic Acids Res. 2022, 50, 3226
→ Highlighted in Trends in Plant Science
98 - Epigenomic features of DNA G-quadruplexes and their roles in regulating gene transcription in rice
Yilong Feng, Shentong Tao, Pengyue Zhang, Francesco Rota Sperti, Guanqing Liu, Xuejiao Cheng, Tao Zhang, Hengxiu, Yu, Xiu-e Wang, Caiyan Chen, David Monchaud and Wenli Zhang
→ Highlighted in Plant Physiology
→ Highlighted as "Technology of the Month" in Trends in Plant Science
97 - Dual targeting of higher-order DNA structures by azacryptands induces DNA junction-mediated DNA damage in cancer cells
Joanna Zell, Katerina Duskova, Leïla Chouh, Madeleine Bossaert, Nicolas Chéron, Anton Granzhan, Sébastien Britton and David Monchaud
Nucleic Acids Res. 2021, 49, 10275
96 - Identifying G-quadruplex-DNA–disrupting small molecules
Jérémie Mitteaux, Pauline Lejault, Filip Wojciechowski, Alexandra Joubert, Julien Boudon, Nicolas Desbois, Claude P. Gros, Robert H. E. Hudson, Jean-Baptiste Boule, Anton Granzhan and David Monchaud
J. Am. Chem. Soc. 2021, 143, 12567
Preprint availbale at bioRxiv
→ Recommended as being of special significance by the CNRS and by Recherche uB
95 - G-quadruplexes mark Alternative-Lengthening-of-Telomeres
Sunny Y. Yang, Emily Y. C. Chang, Joanne Lim, Harwood Kwan, David Monchaud, Stephen Yip, Peter C. Stirling and Judy M. Y. Wong
94 - Differential responses of neurons, astrocytes, and microglia to G-quadruplex stabilization
Natalie Tabor, Conelius Ngwa, Jeremie Mitteaux, Matthew D. Meyer, Jose F. Moruno-Manchon, Liang Zhu, Fudong Liu, David Monchaud, Louise D. McCullough and Andrey S. Tsvetkov
93 - Biomimetic, smart and multivalent ligands for G-quadruplex isolation and bioorthogonal imaging
Francesco Rota Sperti, Thibaut Charbonnier, Pauline Lejault, Joanna Zell, Claire Bernhard, Ibai E. Valverde and David Monchaud
Preprint availbale at bioRxiv
→ highlighted in preLights.
92 - How to untie G-quadruplex knots and why?
Pauline Lejault, Jérémie Mitteaux, Francesco Rota Sperti and David Monchaud
Cell Chem. Biol. 2021, 28, 436
91 - Insights into G-Quadruplex–Hemin Dynamics Using Atomistic Simulations: Implications for Reactivity and Folding
Petr Stadlbauer, Barira Islam, Michal Otyepka, Jielin Chen, David Monchaud, Jun Zhou, Jean-Louis Mergny and Jiri Sponer
J. Chem. Theory Comput. 2021, 17, 1883
Preprint availbale at bioRxiv
90 - DNA folds threaten genetic stability and can be leveraged for chemotherapy
Joanna Zell, Francesco Rota Sperti, Sébastien Britton and David Monchaud
→ Selected as an Editors' choice
89 - The catalytic properties of DNA G-quadruplexes rely on their structural integrity
Jielin Chen, Mingpan Cheng, Jiawei Wang, Dehui Qiu, David Monchaud, Jean-Louis Mergny, Huangxian Ju and Jun Zhou
Chinese J. Catal. 2021, 42, 1102
88- Regulation of autophagy by DNA quadruplexes
Pauline Lejault, Jose F. Moruno-Manchon, Sree M. Vemu, Pedram Honarpisheh, Liang Zhu, Nayun Kim, Akihiko Urayama, David Monchaud, Louise D. McCullough and Andrey S. Tsvetkov
87 - Red wine extract inhibits VEGF secretion and its signalling pathway in retinal ARPE-19 cells to potentially disrupt AMD
Clarisse Cornebise, Flavie Courtaut, Marie Taillandier, Josep Valls-Fonayet, Tristan Richard, David Monchaud, Virginie Aires and Dominique Delmas
→ Invited paper, special issue : Benefits of the Mediterranean Diet–Wine Association, Ed. P. Silva & N. Latruffe.
86 - A Push-Pull Mechanism Helps Design Highly Competent G-Quadruplex-DNA Catalysts
Jielin Chen, Jiawei Wang, Stephanie C. C. van der Lubbe, Mingpan Cheng, Dehui Qiu, David Monchaud, Jean-Louis Mergny, Célia Fonseca Guerra, Huangxian Ju and Jun Zhou
85- Noncovalent dimerization of a G-quadruplex/hemin DNAzyme improves its biocatalytic properties
Yu Cheng, Mingpan Cheng, Jingya Hao, Guoqing Jia, David Monchaud and Can Li
84- Quadruplex detection in human cells
David Monchaud
Annu. Rep. Med. Chem. 2020, 54, 133
Preprint availbale at arXiv:1910.07023 (and/or HAL)
→ Invited paper, special issue : Quadruplex nucleic acids as targets for medicinal chemistry, Ed. S. Neidle.
83 - Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons
Jose F. Moruno-Manchon, Pauline Lejault, Yaoxuan Wang, Brenna McCauley, Pedram Honarpisheh, Diego A. Morales Scheihing, Shivani Singh, Weiwei Dang, Nayun Kim, Akihiko Urayama, Liang Zhu, David Monchaud, Louise D. McCullough and Andrey S. Tsvetkov
→ Recommended as being of special significance by the CNRS and by Recherche uB
→ Highlighted by Sciences & Avenir and Pour La Science
→ Radio broadcast CQFD of the RTS (Radio Télévision Suisse)
82 - An oxidatively damaged G-quadruplex/hemin DNAzyme
Jiawei Wang, Mingpan Cheng, Jielin Chen, Huangxian Ju, David Monchaud, Jean-Louis Mergny and Jun Zhou
81 - DNA junction ligands trigger DNA damage and are synthetic lethal with DNA repair inhibitors in cancer cells
Katerina Duskova, Pauline Lejault, Élie Benchimol, Régis Guillot, Sébastien Britton, Anton Granzhan and David Monchaud
J. Am. Chem. Soc. 2020, 142, 424
80 - Improved performances of catalytic G-quadruplexes (G4-DNAzymes) via the chemical modifications of the DNA backbone to provide G-quadruplexes with double 3'-external G-quartets
Antonella Virgilio, Veronica Esposito, Pauline Lejault, David Monchaud and Aldo Galeone
Int. J. Biol. Macromol. 2020, 151, 976.
79 - Applications of guanine-quartets in nanotechnology and chemical biology
Loic Stefan and David Monchaud
→ Recommended by Recherche uB
78 - The scope of application of macrocyclic polyamines beyond metal chelation
Pauline Lejault, Katerina Duskova, Claire Bernhard, Ibai E. Valverde, Anthony Romieu and David Monchaud
Eur. J. Org. Chem. 2019, 6146.
→ Flagged as "Very Important Paper" (VIP) by the editors
→ Selected for the front cover
77 - Small-molecule affinity capture of DNA/RNA quadruplexes and their identification in vitro and in vivo through the G4RP protocol
Isaline Renard, Michael Grandmougin, Apolline Roux, Sunny Y. Yang, Pauline Lejault, Marc Pirrotta, Judy M. Y. Wong and David Monchaud
Nucleic Acids Res. 2019, 47, 5502.
→ Selected for the front cover
76 - Identification of three-way DNA junction ligands through screening of chemical libraries and validation by complementary in vitro assays
Katerina Duskova, Jérémy Lamarche, Souheila Amor, Coralie Caron, Nicolas Queyriaux, Marie Gaschard, Marie-José Penouilh, Guillaume de Robillard, Dominique Delmas, Charles H. Devillers, Anton Granzhan, Marie-Paule Teulade-Fichou, Murielle Chavarot-Kerlidou, Bruno Therrien, Sébastien Britton and David Monchaud
75 - 2nd PSL Chemical Biology Symposium (2019): At the Crossroads of Chemistry and Biology
Marco Lucchino, Anne Billet, Antoine Versini, Harikrishna Bavireddi, Bhanu‐Das Dasari, Sylvain Debieu, Ludovic Colombeau, Tatiana Cañeque, Alain Wagner, Géraldine Masson, Frédéric Taran, Philippe Karoyan, Muriel Delepierre, Christine Gaillet, Anne Houdusse, Sébastien Britton, Frédéric Schmidt, Jean‐Claude Florent, Philippe Belmont, David Monchaud, Janine Cossy, Christophe Thomas, Arnaud Gautier, Ludger Johannes, Raphaël Rodriguez
74 - Transcriptome-wide identification of transient RNA G-quadruplexes in human cells.
Sunny Y. Yang, Pauline Lejault, Sandy Chevrier, Romain Boidot, A. Gordon Robertson, Judy M. Y. Wong, David Monchaud
→ Recommended as being of special significance by F1000 Faculty (see: F1000 recommendation).
→ Recommended by Recherche uB
73 - How Proximal Nucleobases Regulate the Catalytic Activity of G-quadruplex/Hemin DNAzymes.
Jielin Chen, Yingying Zhang, Mingpan Cheng, Yuehua Gu, Jiri Sponer, David Monchaud, Jean-Louis Mergny, Huangxian Ju, Jun Zhou
72 - TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro.
Ludivine Guyon, Marc Pirrotta, Katerina Duskova, Anton Granzhan, Marie-Paule Teulade-Fichou, David Monchaud
Nucleic Acids Res. 2018, 46, e16.
71 - Thermophilic tetramolecular G-quadruplex/hemin DNAzyme.
Huangxian Ju, Yuehua Guo, Jielin Chen, Mingpan Cheng, David Monchaud, Jun Zhou
Angew. Chem. Int. Ed. 2017, 56, 16636
70 - Quadruplexes d'ADN: structures, fonctions & détection.
David Monchaud
Médecine/Science 2017, 33, 1040 (science popularization article)
69 - ADN (acide désoxyribonucléique) ou DNA (deoxyribonucleic acid).
Michel Morange, David Monchaud, Michel Duguet
Encyclopædia Universalis 2017 (science popularization article)
68 - The G-quadruplex specific RNA helicase DHX36 regulates p53 pre-mRNA 3'-end processing following UV-induced DNA damage.
Michelle Newman, Rym Sfaxi, Abhijit Saha, David Monchaud, Marie-Paule Teulade-Fichou, Stéphan Vagner
67 - Cellular detection of G-quadruplexes by optical imaging methods.
Souheila Amor, Sunny Y. Yang, Judy M. Y. Wong, David Monchaud,
Curr. Protoc. Cell Biol. 2017, 76, 4.33.1.
66 - Real-time and quantitative fluorescent live-cell imaging with quadruplex-specific red-edge probe (G4-REP).
Sunny Y. Yang, Souheila Amor, Aurélien Laguerre, Judy M. Y. Wong, David Monchaud
Biochim. Biophys. Acta 2017, 1861, 1312.
→ Invited paper, special issue : G-quadruplexes, Eds. D. Montesarchio & C. Giancola.
65 - Selective luminescent labeling of DNA and RNA quadruplexes by π-extended ruthenium light-up probes.
Dounia Saadallah, Mehdi Bellakhal, Souheila Amor, Jean-Francois Lefebvre, Murielle Chavarot-Kerlidou, Isabelle Baussanne, Cécile Moucheron, Martine Demeunynck, David Monchaud
→ Selected for the cover
→ Flagged as "Hot paper" by the editors
64 - Computational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengers.
Jie Zhou, Benjamin T. Roembke, Gabor Paragi, Aurélien Laguerre, Herman O. Sintim, Célia Fonseca Guerra, David Monchaud
63 - Direct visualization of both DNA and RNA quadruplexes in human cells via an uncommon spectroscopic mechanism.
Aurélien Laguerre, Judy M. Y. Wong, David Monchaud
→ Recommended as being of special significance by the CNRS
→ Recommended by Recherche uB
62 - DNA structure-specific sensitization of a metalloporphyrin leads to an efficient in vitro quadruplex detection molecular tool.
Pape Diaba Diabate, Aurélien Laguerre, Marc Pirrotta, Nicolas Desbois, Julien Boudon, Claude P. Gros, David Monchaud
→ Themed issue on Nitrogen Ligands, Eds. C. P. Gros & F. Denat
→ Selected for the cover
61 - Blending quadruplexes and Bordeaux: a Grand Cru!
Liliya Yatsunyk, David Monchaud, Dipankar Sen
Cell Chem. Biol. 2016, 23, 320
60 - Pre-folded synthetic G-quartets display enhanced bioinspired properties.
Theodore Flack, Thibaut Constantin, Sylvain Penasse, Jérôme Dejeu, Béatrice Gennaro, Muriel Jourdan, Aurelien Laguerre, Marc Pirrotta, David Monchaud, Nicolas Spinelli, Eric Defrancq
Chem. Eur. J., 2016, 22, 1760.
59 - Carbon nanotube-protamine hybrid: evaluation of DNA cell penetration.
Cécile Caoduro, Raoudha Kacem, Khaoula Boukari, Fabien Picaud, Claire-Hélène Brachais, David Monchaud, Christophe Borg, Hatem Boulahdour, Tijani Gharbi, Régis Delage-Mouroux, Eric Hervouet, Marc Pudlo
58 - Synthetic G-quartets as versatile nanotools for the luminescent detection of G-quadruplexes.
Aurelien Laguerre, Marine Levillain, Loic Stefan, Romain Haudecoeur, Fares Katranji, Marc Pirrotta, David Monchaud
→ Invited paper, special issue : Supramolecular Chemistry, Ed. B. Therrien.
57 - Nature-inspired strategies to target DNA/RNA-quadruplexes.
Aurelien Laguerre, Loic Stefan, David Monchaud
Biological relevance & therapeutic applications of DNA- and RNA-quadruplexes, 2015, 206.
Ed. D. Monchaud, © 2015 Future Science, Ltd.
56 - How has the field of quadruplex ligands fared since 1997?
Xiaogang Qu, Ta-Chau Chang, Kogularamanan Suntharalingam, David Monchaud
Biological relevance & therapeutic applications of DNA- and RNA-quadruplexes, 2015, 152.
Ed. D. Monchaud, © 2015 Future Science, Ltd.
55 - Double helix versus quadruple helix.
David Monchaud
Biological relevance & therapeutic applications of DNA- and RNA-quadruplexes, 2015, 2.
Ed. D. Monchaud, © 2015 Future Science, Ltd.
54 - The biotechnological applications of G-quartets.
David Monchaud
DNA in Supramolecular Chemistry and Nanotechnology, 2015, Chapter III.5, 229.
Eds. E. Stulz & G. H. Clever, © 2015 John Wiley & Sons, Ltd.
53 - Visualization of RNA-quadruplexes in live cells.
Aurélien Laguerre, Kyle Hukezalie, Pascale Winckler, Fares Katranji, Gaetan Chanteloup, Marc Pirrotta, Jean-Marie Perrier-Cornet, Judy M. Y. Wong, David Monchaud
J. Am. Chem. Soc., 2015, 137, 8521.
52 - Surface-promoted aggregation of amphiphilic quadruplex ligands drives their selectivity for alternative DNA structures.
Aurélien Laguerre, Yi Chang, Marc Pirrotta, Nicolas Desbois, Claude P. Gros, Eric Lesniewska, David Monchaud
Org. Biomol. Chem., 2015, 13, 7034.
51 - Cationic azacryptands as selective three-way DNA junction binding agents.
Jana Novotna, Aurélien Laguerre, Anton Granzhan, Marc Pirrotta, Marie-Paule Teulade-Fichou, David Monchaud
Org. Biomol. Chem., 2015, 13, 215.
50 - A twice-as-smart synthetic G-quartet: PyroTASQ is both a smart quadruplex ligand & a smart fluorescent probe.
Aurélien Laguerre, Loic Stefan, Manuel Larrouy, David Genest, Jana Novotna, Marc Pirrotta, David Monchaud
J. Am. Chem. Soc., 2014, 136, 12406.
49 - Xanthine-based gold(I) N-heterocyclic carbene complexes: synthesis and anticancer evaluation.
Benoit Bertrand, Geny Groothuis, Angela Casini, Loic Stefan, Ewen Bodio, Philippe Richard, Pierre Le Gendre, David Monchaud, Michel Picquet
J. Biol. Inorg. Chem., 2014, 19, S589.
48 - Caffeine-based gold(I) N-heterocyclic carbenes as possible anticancer agents: synthesis and biological properties.
Benoit Bertrand, Loic Stefan, Marc Pirrotta, David Monchaud, Ewen Bodio, Philippe Richard, Pierre Le Gendre, Elena Warmerdam, Marina de Jager, Geny Groothuis, Michel Picquet, Angela Casini
→ Recommended as being of special significance by the American Association for the Advancement of Science (see: AAAS recommendation)
47 - Porphyrin-based design of bioinspired multi-target quadruplex ligands.
Aurélien Laguerre, Nicolas Desbois, Loic Stefan, Philippe Richard, Claude P. Gros, David Monchaud
→ Special issue : DNA, RNA & Medicinal chemistry (Eds. S. Neubacher & S. D. Williams)
46 - Surface-immobilized DNAzyme-type biocatalysis.
Loic Stefan, Thomas Lavergne, Nicolas Spinelli, Eric Defrancq, David Monchaud
45 - Multitasking Water-Soluble Synthetic G-Quartets: from preferential RNA-quadruplex interaction to biocatalytic activity.
Romain Haudecoeur, Loic Stefan, David Monchaud
Chem. Eur. J., 2013, 9, 12739.
44 - A model of smart G-quadruplex ligand.
Romain Haudecoeur, Loic Stefan, Franck Denat, David Monchaud
J. Am. Chem. Soc., 2013, 135, 550.
→ Recommended as being of special significance by F1000 Faculty (see: F1000 recommendation).
43 - Closer to nature: an ATP-driven bioinspired catalytic oxidation process.
Loic Stefan, Damien Duret, Nicolas Spinelli, Eric Defrancq, David Monchaud
42 - Assessing the differential affinity of small-molecules for noncanonical DNA structures.
Loic Stefan, Benoit Bertrand, Pierre Le Gendre, Franck Denat, Michel Picquet, David Monchaud
41 - Insights into how nucleotide supplements enhance the peroxidase-mimicking DNAzyme activity of the G-quadruplex/hemin system.
Loic Stefan, Franck Denat, David Monchaud
Nucleic Acids Res., 2012, 40, 8759.
40 - Porphyrin-templated synthetic G-quartet (PorphySQ): a second prototype of G-quartet-based G-quadruplex ligand.
Hai-Jun Xu, Loic Stefan, Romain Haudecoeur, Sophie Vuong, Philippe Richard, Franck Denat, Jean-Michel Barbe, Claude P. Gros, David Monchaud
Org. Biomol. Chem., 2012, 10, 5212.
39 - Identifying three-way DNA junction-specific small-molecules.
Sophie Vuong, Loic Stefan, Pauline Lejault, Yoann Rousselin, Franck Denat, David Monchaud
38 - Deciphering the DNAzyme activity of multimeric quadruplexes: insights into their actual role in the telomerase activity evaluation assay.
Loic Stefan, Franck Denat, David Monchaud
J. Am. Chem. Soc., 2011,133, 20405.
37 - Harnessing nature's insights: synthetic small-molecules with peroxidase-mimicking DNAzyme properties.
Loic Stefan, Hai-Jun Xu, Claude P. Gros, Franck Denat, David Monchaud
Chem. Eur. J., 2011, 17, 10857.
36 - DOTASQ as a prototype of nature-inspired G-quadruplex ligand.
Loic Stefan, Aurore Guédin, Samir Amrane, Nicole Smith, Franck Denat, Jean-Louis Mergny, David Monchaud
Chem. Commun., 2011, 47, 4992.
35 - An acyclic oligoheteroaryle that discriminates strongly between diverse G-quadruplex topologies
Florian Hamon, Eric Largy, Aurore Guédin-Beaurepaire, Myriam Rouchon-Dagois, Assitan Sibide, David Monchaud, Jean-Louis Mergny, Jean-Francois Riou, Chi-Hung Nguyen, Marie-Paule Teulade-Fichou
Angew. Chem. Int. Ed., 2011, 50, 8745.
→ Recommended as being of special significance by F1000 Faculty (see: F1000 recommendation).
34 - Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae
Jasmine S. Smith, Qijun Chen, Liliya A. Yatsunyk, John M. Nicoludis, Mark S. Garcia, Ramon Kranaster, Shankar Balasubramanian, David Monchaud, Marie-Paule Teulade-Fichou, Lara Abramowitz, David C. Schultz, F. Brad Johnson
Nature Struct. Mol. Biol., 2011, 18, 478.
33 - Recognition of G-quadruplex DNA by triangular star-shaped compounds: with or without side chains?
Hélène Bertrand, Anton Granzhan, David Monchaud, Nicolas Saettel, Régis Guillot, Sarah Clifford, Aurore Guédin, Jean-Louis Mergny, Marie-Paule Teulade-Fichou
Chem. Eur. J., 2011, 17, 4529.
32 - “One ring to bind them all” – Part I: The efficiency of the macrocyclic scaffold for G-quadruplex DNA recognition
David Monchaud, Anton Granzhan, Nicolas Saettel, Aurore Guédin, Jean-Louis Mergny, Marie-Paule Teulade-Fichou
J. Nucleic Acids, 2010, 2010, ID460561.
31 - “One ring to bind them all” – Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-type Macrocycles.
Anton Granzhan, David Monchaud, Nicolas Saettel, Aurore Guédin, Jean-Louis Mergny, and Marie-Paule Teulade-Fichou
J. Nucleic Acids, 2010, 2010, ID525862.
30 - Template-Assembled Synthetic G-Quadruplex (TASQ): A Useful System for Investigating the Interactions of Ligands with Constrained Quadruplex Topologies.
Pierre Murat, Romaric Bonnet, Agéline Van der Heyden, Nicolas Spinelli, Pierre Labbé, David Monchaud, Marie-Paule Teulade-Fichou, Pascal Dumy, Eric Defrancq
Chem. Eur. J., 2010, 16, 6106.
29 - G4-FID: a fluorescent DNA probe displacement assay for rapid evaluation of quadruplex ligands.
David Monchaud, Marie-Paule Teulade-Fichou
in "G-Quadruplex DNA: Methods and Protocols", P. Baumann (Ed.)
Meth. Mol. Biol., 2010, 608, 257-271.
28 - Synthesis and evaluation of fused bispyrimidinoacridines as novel pentacyclic analogues of quadruplex-binders BRACO-19.
Julien Debray, Walid Zeghida, Muriel Jourdan, David Monchaud, Marie-Louise Dheu-Andries, Pascal Dumy, Marie-Paule Teulade-Fichou, Martine Demeunynck
Org. Biomol. Chem., 2009, 7, 5219-5228.
27 - Exclusive platination of loop adenines in the human telomeric G-quadruplex.
Hélène Bertrand, Sophie Bombard, David Monchaud, Eric Talbot, Aurore Guedin, Jean-Louis Mergny, Renate Grünter, Patrick J. Bednarski, Marie-Paule Teulade-Fichou
Org. Biomol. Chem., 2009, 7, 2864-2871.
26 - Engineering bisquinolinium/thiazole orange conjugates for fluorescent sensing of G-quadruplex DNA.
Peng Yang, Anne De Cian, Marie-Paule Teulade-Fichou, Jean-Louis Mergny, David Monchaud
Angew. Chem. Int. Ed., 2009, 48, 2188-2191
25 - New platinum(II) complexes targeting the loops of the human telomeric G-quadruplex.
Hélène Bertrand, Sophie Bombard, David Monchaud, Marie-Paule Teulade-Fichou
Nucleic Acids Symp. Ser., 2008, 52, 163-164
24 - Ligands playing musical chairs with G-quadruplex DNA: A rapid and simple displacement assay for identifying selective G-quadruplex binders.
David Monchaud, Clémence Allain, Hélène Bertrand, Nicolas Smargiasso, Frédéric Rosu, Valérie Gabelica, Anne De Cian, Jean-Louis Mergny, Marie-Paule Teulade-Fichou
Biochimie, 2008, 90, 1207-1223
23 - A hitchhiker's guide to G-quadruplex ligands
David Monchaud, Marie-Paule Teulade-Fichou
Org. Biomol. Chem., 2008, 4, 627-636
→ In the 25 most cited articles in ISI Web of knowledge (entry "quadruplex") out of >11,000 references!
22 - A Metal-Mediated Conformational Switch Controls G-Quadruplex Binding Affinity.
David Monchaud, Peng Yang, Laurent Lacroix, Marie-Paule Teulade-Fichou, Jean-Louis Mergny
Angew. Chem. Int. Ed., 2008, 47, 4858-4861
21 - Plasmodium Telomeric Sequences: Structure, Stability and Quadruplex Targeting by Small Compounds.
Anne De Cian, Philippe Grellier, Elisabeth Mouray, Delphine Depoix, Hélène Bertrand, David Monchaud, Marie-Paule Teulade-Fichou, Jean-Louis Mergny, Patrizia Alberti
ChemBioChem, 2008, 9, 2730-2739
20 - Inhibition of Dicing of Guanosine-Rich shRNAs by Quadruplex-Binding Compounds.
Anja Henn, Astrid Joachimi, Diana P. N. Gonçalves, David Monchaud, Marie-Paule Teulade-Fichou, Jeremy K. M. Sanders, Jörg S. Hartig
ChemBioChem, 2008, 9, 2722-2729
19 - The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes.
Hélène Bertrand, David Monchaud, Anne De Cian, Régis Guillot, Jean-Louis Mergny and Marie-Paule Teulade-Fichou
Org. Biomol. Chem., 2007, 5, 2555-2559
18 - A platinum-quinacridine hybrid as a G-quadruplex ligand.
Hélène Bertrand, Sophie Bombard, David Monchaud and Marie-Paule Teulade-Fichou
J. Biol. Inorg. Chem., 2007, 12, 1003-1014
17 - Thiazole Orange: A Useful Probe for Fluorescence Sensing of G-Quadruplex-Ligand Interactions.
David Monchaud, Clémence Allain, Marie -Paule Teulade-Fichou
Nucleosides, Nucleotides Nucleic Acids, 2007, 26, 1585-1588
16 - G-Quadruplex Recognition by Quinacridines: a SAR, NMR, and Biological Study.
Candide Hounsou, Lionel Guittat, David Monchaud, Muriel Jourdan, Nicolas Saettel, Jean-Louis Mergny, Marie-Paule Teulade-Fichou
15 - Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action.
Anne De Cian, Gael Cristofari, Patrick Reichenbach, Elsa De Lemos, David Monchaud, Marie-Paule Teulade-Fichou, Kazuo Shin-ya, Laurent Lacroix, Joachim Lingner, Jean-Louis Mergny
Proc. Natl. Acad. Sci. USA, 2007, 104, 17347-17352
14 - Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds.
Anne De Cian, Elsa DeLemos, Jean-Louis Mergny, Marie-Paule Teulade-Fichou, and David Monchaud
J. Am. Chem. Soc. , 2007, 129, 1856-1857
13 - Beneficial Effect of Mukaiyama Reagent on Macrobislactamization Reactions.
Lucie Vandromme, David Monchaud, Marie-Paule Teulade-Fichou
12 - Development of a fluorescent intercalator displacement assay (G4-FID) for establishing quadruplex-DNA affinity and selectivity of putative ligands.
David Monchaud, Clémence Allain, Marie-Paule Teulade-Fichou
Bioorg. Med. Chem. Lett., 2006, 16, 4842-4845
11 - FRET Templated by G-Quadruplex DNA: A Specific Ternary Interaction Using an Original Pair of Donor/Acceptor Partners.
Clémence Allain, David Monchaud, and Marie-Paule Teulade-Fichou
J. Am. Chem. Soc., 2006, 128, 11890-11893
10 - Customized fused aromatics for structural recognition of nucleic acids.
Marie-Paule Teulade-Fichou, Markus Kaiser, Matthieu Sainlos, Sophie Bombard, David Monchaud, Clémence Jacquelin, Candide Hounsou and Rémy Lartia
Coll. Symp. Series, 2005, 7, 245-248
09 - Biphasic Enantioselective Olefin Epoxidation Using Tropos Dibenzoazepinium Catalysts.
Jérôme Vachon, Céline Pérollier, David Monchaud, Claire Marsol, Klaus Ditrich, and Jérôme Lacour
J. Org. Chem., 2005, 70, 5903-5911
08 - Large-Scale Synthesis and Resolution of TRISPHAT [Tris(tetrachlorobenzenediolato) Phosphate(V)] Anion.
France Favarger, Catherine Goujon-Ginglinger, David Monchaud, and Jérôme Lacour
J. Org. Chem., 2004, 69, 8521-8524
07 - Synthesis, Enantiomeric Conformations, and Stereodynamics of Aromatic ortho-Substituted Disulfones.
Jérôme Lacour, David Monchaud, Jiri Mareda, France Favarger, Gérald Bernardinelli
Helvetica Chim. Acta, 2003, 86, 65-81
06 - Effect of the medium on the oxaziridinium-catalyzed enantioselective epoxidation.
Jerome Lacour, David Monchaud, Claire Marsol
Tetrahedron Lett., 2002, 43, 8257-8260
05 - Ion-Pair-Mediated Asymmetric Synthesis of a Configurationally Stable Mononuclear Tris(diimine)-Iron(II) Complex.
David Monchaud, Jonathan J. Jodry, Didier Pomeranc, Valérie Heitz, Jean-Claude Chambron, Jean-Pierre Sauvage, Jérôme Lacour
Angew. Chem. Int. Ed., 2002, 41, 2317-2319
04 - TRISPHAT Anion. An Efficient NMR Chiral Shift Counterion for Cationic Tricarbonyl Manganese Complexes with Planar Chirality.
José Giner Planas, Damien Prim, Eric Rose, Françoise Rose-Munch, David Monchaud and Jérôme Lacour
Organometallics, 2001, 20, 4107-4110
03 - Synthesis, Enantiomeric Conformations, and Stereodynamics of Aromatic ortho-Substituted Disulfones.
Jérôme Lacour, David Monchaud, Gérald Bernardinelli, and France Favarger
Org. Lett., 2001, 3, 1407-1410
02 - Configurational ordering of a cationic dinuclear triple helicate by chiral TRISPHAT anions.
Jérome Lacour, Jonathan J. Jodry, David Monchaud
Chem. Commun., 2001, 2302-2303
01 - TRISPHAT salts. Efficient NMR chiral shift and resolving agents for substituted cyclometallated ruthenium bis(diimine) complexes.
David Monchaud, Jérôme Lacour, Christophe Coudret, Sandrine Fraysse