2016-2020
89- Regulation of autophagy by DNA quadruplexes
Pauline Lejault, Jose F. Moruno-Manchon, Sree M. Vemu, Pedram Honarpisheh, Liang Zhu, Nayun Kim, Akihiko Urayama, David Monchaud, Louise D. McCullough and Andrey S. Tsvetkov
88 - Red wine extract inhibits VEGF secretion and its signalling pathway in retinal ARPE-19 cells to potentially disrupt AMD
Clarisse Cornebise, Flavie Courtaut, Marie Taillandier, Josep Valls-Fonayet, Tristan Richard, David Monchaud, Virginie Aires and Dominique Delmas
→ Invited paper, special issue : Benefits of the Mediterranean Diet–Wine Association, Ed. P. Silva & N. Latruffe.
87 - A Push-Pull Mechanism Helps Design Highly Competent G-Quadruplex-DNA Catalysts
Jielin Chen, Jiawei Wang, Stephanie C. C. van der Lubbe, Mingpan Cheng, Dehui Qiu, David Monchaud, Jean-Louis Mergny, Célia Fonseca Guerra, Huangxian Ju and Jun Zhou
86- Noncovalent dimerization of a G-quadruplex/hemin DNAzyme improves its biocatalytic properties
Yu Cheng, Mingpan Cheng, Jingya Hao, Guoqing Jia, David Monchaud and Can Li
85- Quadruplex detection in human cells
David Monchaud
Annu. Rep. Med. Chem. 2020, 54, 133
Preprint availbale at arXiv:1910.07023 (and/or HAL)
→ Invited paper, special issue : Quadruplex nucleic acids as targets for medicinal chemistry, Ed. S. Neidle.
84 - Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons
Jose F. Moruno-Manchon, Pauline Lejault, Yaoxuan Wang, Brenna McCauley, Pedram Honarpisheh, Diego A. Morales Scheihing, Shivani Singh, Weiwei Dang, Nayun Kim, Akihiko Urayama, Liang Zhu, David Monchaud, Louise D. McCullough and Andrey S. Tsvetkov
→ Recommended as being of special significance by the CNRS and by Recherche uB
→ Highlighted by Sciences & Avenir and Pour La Science
→ Radio broadcast CQFD of the RTS (Radio Télévision Suisse)
83 - An oxidatively damaged G-quadruplex/hemin DNAzyme
Jiawei Wang, Mingpan Cheng, Jielin Chen, Huangxian Ju, David Monchaud, Jean-Louis Mergny and Jun Zhou
82 - DNA junction ligands trigger DNA damage and are synthetic lethal with DNA repair inhibitors in cancer cells
Katerina Duskova, Pauline Lejault, Élie Benchimol, Régis Guillot, Sébastien Britton, Anton Granzhan and David Monchaud
J. Am. Chem. Soc. 2020, 142, 424
81 - Improved performances of catalytic G-quadruplexes (G4-DNAzymes) via the chemical modifications of the DNA backbone to provide G-quadruplexes with double 3'-external G-quartets
Antonella Virgilio, Veronica Esposito, Pauline Lejault, David Monchaud and Aldo Galeone
Int. J. Biol. Macromol. 2020, 151, 976.
80 - Applications of guanine-quartets in nanotechnology and chemical biology
Loic Stefan and David Monchaud
→ Recommended by Recherche uB
79 - The scope of application of macrocyclic polyamines beyond metal chelation
Pauline Lejault, Katerina Duskova, Claire Bernhard, Ibai E. Valverde, Anthony Romieu and David Monchaud
Eur. J. Org. Chem. 2019, 6146.
→ Flagged as "Very Important Paper" (VIP) by the editors
→ Selected for the front cover
78 - Small-molecule affinity capture of DNA/RNA quadruplexes and their identification in vitro and in vivo through the G4RP protocol
Isaline Renard, Michael Grandmougin, Apolline Roux, Sunny Y. Yang, Pauline Lejault, Marc Pirrotta, Judy M. Y. Wong and David Monchaud
Nucleic Acids Res. 2019, 47, 5502.
→ Selected for the front cover
77 - Identification of three-way DNA junction ligands through screening of chemical libraries and validation by complementary in vitro assays
Katerina Duskova, Jérémy Lamarche, Souheila Amor, Coralie Caron, Nicolas Queyriaux, Marie Gaschard, Marie-José Penouilh, Guillaume de Robillard, Dominique Delmas, Charles H. Devillers, Anton Granzhan, Marie-Paule Teulade-Fichou, Murielle Chavarot-Kerlidou, Bruno Therrien, Sébastien Britton and David Monchaud
76 - 2nd PSL Chemical Biology Symposium (2019): At the Crossroads of Chemistry and Biology
Marco Lucchino, Anne Billet, Antoine Versini, Harikrishna Bavireddi, Bhanu‐Das Dasari, Sylvain Debieu, Ludovic Colombeau, Tatiana Cañeque, Alain Wagner, Géraldine Masson, Frédéric Taran, Philippe Karoyan, Muriel Delepierre, Christine Gaillet, Anne Houdusse, Sébastien Britton, Frédéric Schmidt, Jean‐Claude Florent, Philippe Belmont, David Monchaud, Janine Cossy, Christophe Thomas, Arnaud Gautier, Ludger Johannes, Raphaël Rodriguez
75 - Transcriptome-wide identification of transient RNA G-quadruplexes in human cells.
Sunny Y. Yang, Pauline Lejault, Sandy Chevrier, Romain Boidot, A. Gordon Robertson, Judy M. Y. Wong, David Monchaud
→ Recommended as being of special significance by F1000 Faculty (see: F1000 recommendation).
→ Recommended by Recherche uB
74 - How Proximal Nucleobases Regulate the Catalytic Activity of G-quadruplex/Hemin DNAzymes.
Jielin Chen, Yingying Zhang, Mingpan Cheng, Yuehua Gu, Jiri Sponer, David Monchaud, Jean-Louis Mergny, Huangxian Ju, Jun Zhou
73 - TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro.
Ludivine Guyon, Marc Pirrotta, Katerina Duskova, Anton Granzhan, Marie-Paule Teulade-Fichou, David Monchaud
Nucleic Acids Res. 2018, 46, e16.
72 - Thermophilic tetramolecular G-quadruplex/hemin DNAzyme.
Huangxian Ju, Yuehua Guo, Jielin Chen, Mingpan Cheng, David Monchaud, Jun Zhou
Angew. Chem. Int. Ed. 2017, 56, 16636
71 - Quadruplexes d'ADN: structures, fonctions & détection.
David Monchaud
Médecine/Science 2017, 33, 1040 (science popularization article)
70 - ADN (acide désoxyribonucléique) ou DNA (deoxyribonucleic acid).
Michel Morange, David Monchaud, Michel Duguet
Encyclopædia Universalis 2017 (science popularization article)
69 - The G-quadruplex specific RNA helicase DHX36 regulates p53 pre-mRNA 3'-end processing following UV-induced DNA damage.
Michelle Newman, Rym Sfaxi, Abhijit Saha, David Monchaud, Marie-Paule Teulade-Fichou, Stéphan Vagner
68 - Cellular detection of G-quadruplexes by optical imaging methods.
Souheila Amor, Sunny Y. Yang, Judy M. Y. Wong, David Monchaud,
Curr. Protoc. Cell Biol. 2017, 76, 4.33.1.
67 - Real-time and quantitative fluorescent live-cell imaging with quadruplex-specific red-edge probe (G4-REP).
Sunny Y. Yang, Souheila Amor, Aurélien Laguerre, Judy M. Y. Wong, David Monchaud
Biochim. Biophys. Acta 2017, 1861, 1312.
→ Invited paper, special issue : G-quadruplexes, Eds. D. Montesarchio & C. Giancola.
66 - Selective luminescent labeling of DNA and RNA quadruplexes by π-extended ruthenium light-up probes.
Dounia Saadallah, Mehdi Bellakhal, Souheila Amor, Jean-Francois Lefebvre, Murielle Chavarot-Kerlidou, Isabelle Baussanne, Cécile Moucheron, Martine Demeunynck, David Monchaud
→ Selected for the cover
→ Flagged as "Hot paper" by the editors
65 - Computational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengers.
Jie Zhou, Benjamin T. Roembke, Gabor Paragi, Aurélien Laguerre, Herman O. Sintim, Célia Fonseca Guerra, David Monchaud
64 - Direct visualization of both DNA and RNA quadruplexes in human cells via an uncommon spectroscopic mechanism.
Aurélien Laguerre, Judy M. Y. Wong, David Monchaud
→ Recommended as being of special significance by the CNRS
→ Recommended by Recherche uB
63 - DNA structure-specific sensitization of a metalloporphyrin leads to an efficient in vitro quadruplex detection molecular tool.
Pape Diaba Diabate, Aurélien Laguerre, Marc Pirrotta, Nicolas Desbois, Julien Boudon, Claude P. Gros, David Monchaud
→ Themed issue on Nitrogen Ligands, Eds. C. P. Gros & F. Denat
→ Selected for the cover
62 - Blending quadruplexes and Bordeaux: a Grand Cru!
Liliya Yatsunyk, David Monchaud, Dipankar Sen
Cell Chem. Biol. 2016, 23, 320
61 - Pre-folded synthetic G-quartets display enhanced bioinspired properties.
Theodore Flack, Thibaut Constantin, Sylvain Penasse, Jérôme Dejeu, Béatrice Gennaro, Muriel Jourdan, Aurelien Laguerre, Marc Pirrotta, David Monchaud, Nicolas Spinelli, Eric Defrancq
Chem. Eur. J., 2016, 22, 1760.
60 - Carbon nanotube-protamine hybrid: evaluation of DNA cell penetration.
Cécile Caoduro, Raoudha Kacem, Khaoula Boukari, Fabien Picaud, Claire-Hélène Brachais, David Monchaud, Christophe Borg, Hatem Boulahdour, Tijani Gharbi, Régis Delage-Mouroux, Eric Hervouet, Marc Pudlo